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Tag Content
UUCD2 ID IUUC-Sha-107339
UUCD1 version UUC-SaH-00591
Ensembl Protein ID ENSSHAP00000014566.1
UniProt Accession G3WGL1; G3WGL1_SARHA
Genbank Protein ID ENSSHAP00000014566
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01018085
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000012435.1 ENSSHAT00000014688.1 ENSSHAP00000014566.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.80e-58 192.0 409 443
UBD/Beta-Prp 6.40e-69 232.6 323 487
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 409  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 443
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 323  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 406
           445579*************9..8**************************************..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 407  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 487
           **************9..***********************************99.************..99**************7 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MEDQNEDESP KKNTLWQISN GTSSVIVSRK RPSEGNYQKE KDLCIKYFDQ WSESDQVEFV 60
EHLISRMCHY QHGHINSYLK PMLQRDFITA LPEQGLDHIA ENILSYLDAR SLCAAELVCK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107339|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATAGTGGCTA TTATTTGCCA CTGGTGCCAT GGTAGGTGTA TGGATTGCTT TCTGTCTTTC 60
CAACAGTTAC CGAAGTGCAT GTTTGGGATT TTGTTGAAGA AAACTGGATA CAGTAAAGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107339|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
KEGG shr:100923383
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 99.39 0.00e+00 1016.00
IUUC-Apl-003449 Anas platyrhynchos 99.22 0.00e+00 1048.00
IUUC-Aca-004341 Anolis carolinensis 98.87 0.00e+00 913.00
IUUC-Ame-011393 Astyanax mexicanus 90.59 0.00e+00 958.00
IUUC-Bta-012920 Bos taurus 99.22 0.00e+00 1050.00
IUUC-Cja-018879 Callithrix jacchus 99.39 0.00e+00 1016.00
IUUC-Cfa-020021 Canis familiaris 99.39 0.00e+00 1016.00
IUUC-Cpo-022151 Cavia porcellus 99.02 0.00e+00 1043.00
IUUC-Csa-024095 Chlorocebus sabaeus 99.41 0.00e+00 1051.00
IUUC-Cho-024658 Choloepus hoffmanni 99.07 6.00e-126 444.00
IUUC-Dre-028160 Danio rerio 90.50 0.00e+00 960.00
IUUC-Dno-029485 Dasypus novemcinctus 88.72 0.00e+00 920.00
IUUC-Dor-030498 Dipodomys ordii 98.99 0.00e+00 1011.00
IUUC-Eca-033804 Equus caballus 99.39 0.00e+00 1015.00
IUUC-Fca-035887 Felis catus 99.41 0.00e+00 1053.00
IUUC-Fal-036783 Ficedula albicollis 99.41 0.00e+00 1053.00
IUUC-Gmo-038590 Gadus morhua 91.70 0.00e+00 933.00
IUUC-Gga-040628 Gallus gallus 99.22 0.00e+00 1050.00
IUUC-Gac-041305 Gasterosteus aculeatus 91.30 0.00e+00 935.00
IUUC-Ggo-044604 Gorilla gorilla 99.39 0.00e+00 1016.00
IUUC-Hsa-046139 Homo sapiens 99.39 0.00e+00 1016.00
IUUC-Lch-050460 Latimeria chalumnae 96.67 0.00e+00 1028.00
IUUC-Laf-053968 Loxodonta africana 99.41 0.00e+00 1052.00
IUUC-Mcc-055822 Macaca mulatta 96.19 0.00e+00 1040.00
IUUC-Mga-059225 Meleagris gallopavo 99.02 0.00e+00 1043.00
IUUC-Mvi-060284 Microbotryum violaceum 44.65 5.00e-69 256.00
IUUC-Mmr-060746 Microcebus murinus 99.39 0.00e+00 1016.00
IUUC-Mdo-062005 Monodelphis domestica 100.00 0.00e+00 1056.00
IUUC-Mmu-063851 Mus musculus 98.63 0.00e+00 1045.00
IUUC-Mpu-065716 Mustela putorius furo 99.41 0.00e+00 1052.00
IUUC-Mlu-067001 Myotis lucifugus 99.41 0.00e+00 1051.00
IUUC-Nle-069788 Nomascus leucogenys 99.39 0.00e+00 1015.00
IUUC-Opr-071229 Ochotona princeps 99.19 0.00e+00 1015.00
IUUC-Ont-071792 Oreochromis niloticus 91.90 0.00e+00 943.00
IUUC-Oan-072782 Ornithorhynchus anatinus 99.41 0.00e+00 1053.00
IUUC-Ocu-074894 Oryctolagus cuniculus 99.41 0.00e+00 1052.00
IUUC-Ola-086985 Oryzias latipes 90.62 0.00e+00 959.00
IUUC-Oga-088604 Otolemur garnettii 93.54 0.00e+00 1034.00
IUUC-Oar-090412 Ovis aries 99.41 0.00e+00 1052.00
IUUC-Ptr-091039 Pan troglodytes 99.19 0.00e+00 1015.00
IUUC-Pan-092770 Papio anubis 99.39 0.00e+00 1004.00
IUUC-Psi-093887 Pelodiscus sinensis 99.02 0.00e+00 1044.00
IUUC-Pfo-096783 Poecilia formosa 90.62 0.00e+00 961.00
IUUC-Pva-102547 Pteropus vampyrus 99.19 0.00e+00 1010.00
IUUC-Rno-105246 Rattus norvegicus 98.63 0.00e+00 1046.00
IUUC-Spo-108200 Schizosaccharomyces pombe 32.22 2.00e-67 249.00
IUUC-Tgu-116541 Taeniopygia guttata 99.22 0.00e+00 1048.00
IUUC-Tru-117671 Takifugu rubripes 90.04 0.00e+00 952.00
IUUC-Tni-120359 Tetraodon nigroviridis 90.43 0.00e+00 950.00
IUUC-Tbe-127418 Tupaia belangeri 92.71 0.00e+00 931.00
IUUC-Ttr-129131 Tursiops truncatus 99.39 0.00e+00 1016.00
IUUC-Vpa-130668 Vicugna pacos 99.39 0.00e+00 1016.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 8.00e-159 552.00
Created Date 25-Jun-2017

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