iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	8.20e-08	32.8	201	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 1    llvCPvCqkmvdqtdfeeHlDeCl 24
           +++CPvC+  ++++++++HlD+Cl
   Q: 201  KVSCPVCGVSIPENHINKHLDSCL 224
           69*********************8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEDLAEPRWP PGLAMMKTID DLLRCGICFE YFNIAVIIPQ CSHNYCSLCI RKFLSYKTQC 60
PTCCVAVTEP DLRNNRLLDE LVKSMSFART RLLQFALESP PISPVSSTSK KVVVKVHNVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTATGCCTT GGAATTCTTT TTCCTCCTCA GTCTTCCAAA GCTGTTGACG CCCAACGCAC 60
GAGAACTACA GCTCCCAGCA TTCTGTGCGC TCTCTGTGAG CGCGCCGCAC GTATCTGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR006642--Znf_Rad18_put
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50800--SAP
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02037--SAP

SMART

SM00184--RING
SM00513--SAP
SM00734--ZnF_Rad18

Gene Ontology

GO:0005813--C:centrosome
GO:0016604--C:nuclear body
GO:0042405--C:nuclear inclusion body
GO:0005634--C:nucleus
GO:0097505--C:Rad6-Rad18 complex
GO:0005657--C:replication fork
GO:0035861--C:site of double-strand break
GO:0043142--F:single-stranded DNA-dependent ATPase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0000403--F:Y-form DNA binding
GO:0008270--F:zinc ion binding
GO:0060548--P:negative regulation of cell death
GO:0051984--P:positive regulation of chromosome segregation
GO:0006301--P:postreplication repair
GO:0051865--P:protein autoubiquitination
GO:0006513--P:protein monoubiquitination
GO:0009411--P:response to UV

KEGG

rno:362412

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002086	Ailuropoda melanoleuca	67.49	0.00e+00	650.00
IUUC-Apl-003657	Anas platyrhynchos	49.54	8.00e-104	370.00
IUUC-Aca-005369	Anolis carolinensis	71.83	7.00e-59	219.00
IUUC-Ago-007876	Ashbya gossypii	36.05	5.00e-11	62.40
IUUC-Acl-008246	Aspergillus clavatus	27.89	2.00e-27	116.00
IUUC-Afl-008666	Aspergillus flavus	25.88	8.00e-26	111.00
IUUC-Afu-009052	Aspergillus fumigatus	29.94	4.00e-15	75.90
IUUC-Ani-009488	Aspergillus nidulans	26.32	5.00e-31	129.00
IUUC-Ang-009681	Aspergillus niger	24.52	2.00e-27	116.00
IUUC-Aor-010037	Aspergillus oryzae	26.59	3.00e-13	69.70
IUUC-Ate-010516	Aspergillus terreus	39.29	2.00e-13	68.90
IUUC-Ame-010630	Astyanax mexicanus	41.94	2.00e-79	289.00
IUUC-Bgr-012178	Blumeria graminis	26.26	2.00e-28	119.00
IUUC-Bta-012976	Bos taurus	69.46	8.00e-154	536.00
IUUC-Bci-013680	Botrytis cinerea	27.46	1.00e-15	77.80
IUUC-Cja-019453	Callithrix jacchus	74.65	0.00e+00	643.00
IUUC-Cfa-020856	Canis familiaris	74.75	0.00e+00	632.00
IUUC-Cpo-021950	Cavia porcellus	72.95	3.00e-180	624.00
IUUC-Csa-023997	Chlorocebus sabaeus	75.45	0.00e+00	628.00
IUUC-Cho-024771	Choloepus hoffmanni	73.21	2.00e-79	289.00
IUUC-Cgl-026668	Colletotrichum gloeosporioides	26.86	7.00e-16	78.60
IUUC-Cme-027202	Cyanidioschyzon merolae	36.47	6.00e-13	68.60
IUUC-Dre-028479	Danio rerio	46.60	1.00e-73	270.00
IUUC-Dno-028943	Dasypus novemcinctus	75.65	5.00e-177	613.00
IUUC-Dor-031046	Dipodomys ordii	68.72	6.00e-135	474.00
IUUC-Dse-031235	Dothistroma septosporum	28.04	2.00e-13	70.90
IUUC-Ete-032503	Echinops telfairi	59.90	5.00e-113	400.00
IUUC-Eca-033725	Equus caballus	79.24	0.00e+00	658.00
IUUC-Eeu-034573	Erinaceus europaeus	69.57	4.00e-115	408.00
IUUC-Fca-036495	Felis catus	70.24	2.00e-171	595.00
IUUC-Fal-036791	Ficedula albicollis	55.20	6.00e-94	337.00
IUUC-Fox-037868	Fusarium oxysporum	35.71	3.00e-12	66.20
IUUC-Fso-038144	Fusarium solani	28.49	8.00e-16	77.80
IUUC-Gmo-039152	Gadus morhua	41.08	1.00e-63	236.00
IUUC-Ggr-039737	Gaeumannomyces graminis	26.77	1.00e-14	74.30
IUUC-Gga-040788	Gallus gallus	56.84	2.00e-107	382.00
IUUC-Gac-041993	Gasterosteus aculeatus	44.20	3.00e-78	285.00
IUUC-Ggo-044889	Gorilla gorilla	75.94	2.00e-180	625.00
IUUC-Hsa-045957	Homo sapiens	75.80	0.00e+00	627.00
IUUC-Itr-048998	Ictidomys tridecemlineatus	77.09	0.00e+00	667.00
IUUC-Lch-050172	Latimeria chalumnae	52.81	3.00e-64	238.00
IUUC-Loc-052609	Lepisosteus oculatus	46.33	1.00e-83	303.00
IUUC-Lma-053037	Leptosphaeria maculans	23.93	6.00e-18	85.50
IUUC-Laf-053889	Loxodonta africana	67.25	3.00e-139	488.00
IUUC-Mcc-055853	Macaca mulatta	75.60	7.00e-179	620.00
IUUC-Meu-056866	Macropus eugenii	52.20	6.00e-79	287.00
IUUC-Mor-057071	Magnaporthe oryzae	26.80	4.00e-30	125.00
IUUC-Mpo-057628	Magnaporthe poae	25.00	8.00e-14	71.60
IUUC-Mla-058953	Melampsora laricipopulina	31.21	2.00e-12	67.80
IUUC-Mga-059687	Meleagris gallopavo	56.75	1.00e-102	366.00
IUUC-Mvi-060412	Microbotryum violaceum	21.25	1.00e-12	68.20
IUUC-Mmr-061563	Microcebus murinus	77.45	0.00e+00	653.00
IUUC-Mdo-062655	Monodelphis domestica	60.43	4.00e-126	444.00
IUUC-Mmu-063647	Mus musculus	80.57	0.00e+00	727.00
IUUC-Mpu-065778	Mustela putorius furo	76.45	0.00e+00	668.00
IUUC-Mlu-068205	Myotis lucifugus	73.14	4.00e-167	581.00
IUUC-Nfi-068501	Neosartorya fischeri	29.44	4.00e-15	75.90
IUUC-Ncr-068917	Neurospora crassa	26.53	3.00e-16	79.70
IUUC-Nle-068990	Nomascus leucogenys	76.75	0.00e+00	634.00
IUUC-Opr-071146	Ochotona princeps	67.80	1.00e-153	536.00
IUUC-Ont-071835	Oreochromis niloticus	45.72	3.00e-74	272.00
IUUC-Oan-072827	Ornithorhynchus anatinus	40.51	6.00e-43	167.00
IUUC-Ocu-073986	Oryctolagus cuniculus	72.26	7.00e-172	596.00
IUUC-Ola-086997	Oryzias latipes	40.06	1.00e-58	220.00
IUUC-Olu-087771	Ostreococcus lucimarinus	32.00	1.00e-10	61.20
IUUC-Oga-088092	Otolemur garnettii	75.99	0.00e+00	679.00
IUUC-Oar-089651	Ovis aries	74.31	7.00e-167	580.00
IUUC-Ptr-091103	Pan troglodytes	76.20	0.00e+00	630.00
IUUC-Pan-092478	Papio anubis	74.85	1.00e-179	622.00
IUUC-Psi-093356	Pelodiscus sinensis	51.00	9.00e-119	420.00
IUUC-Pfo-096663	Poecilia formosa	57.86	6.00e-47	181.00
IUUC-Pab-098515	Pongo abelii	76.40	0.00e+00	634.00
IUUC-Pca-100588	Procavia capensis	58.10	1.00e-115	409.00
IUUC-Pva-102377	Pteropus vampyrus	77.11	0.00e+00	648.00
IUUC-Pgr-103556	Puccinia graminis	26.26	1.00e-09	58.50
IUUC-Pte-104362	Pyrenophora teres	32.14	2.00e-10	60.10
IUUC-Pyt-104823	Pyrenophora triticirepentis	26.37	4.00e-10	59.30
IUUC-Sce-106454	Saccharomyces cerevisiae	40.00	2.00e-12	67.00
IUUC-Sha-107515	Sarcophilus harrisii	58.77	3.00e-125	441.00
IUUC-Sja-107689	Schizosaccharomyces japonicus	40.00	1.00e-11	63.90
IUUC-Spo-108248	Schizosaccharomyces pombe	42.50	3.00e-14	73.20
IUUC-Ssl-108430	Sclerotinia sclerotiorum	25.71	2.00e-14	74.30
IUUC-Sre-115123	Sporisorium reilianum	23.01	8.00e-13	68.60
IUUC-Ssc-115992	Sus scrofa	73.97	1.00e-133	469.00
IUUC-Tgu-117286	Taeniopygia guttata	54.74	2.00e-99	356.00
IUUC-Tru-117959	Takifugu rubripes	42.74	3.00e-65	242.00
IUUC-Tsy-119286	Tarsius syrichta	57.49	4.00e-118	418.00
IUUC-Tni-120570	Tetraodon nigroviridis	46.87	8.00e-72	263.00
IUUC-Tre-121893	Trichoderma reesei	23.55	4.00e-13	69.30
IUUC-Tvi-122405	Trichoderma virens	24.86	9.00e-13	67.80
IUUC-Tbe-127758	Tupaia belangeri	70.37	1.00e-69	257.00
IUUC-Ttr-128841	Tursiops truncatus	76.71	0.00e+00	629.00
IUUC-Vda-130021	Verticillium dahliae	30.94	7.00e-16	77.40
IUUC-Vpa-130169	Vicugna pacos	70.99	1.00e-135	476.00
IUUC-Xtr-132308	Xenopus tropicalis	53.26	2.00e-105	375.00
IUUC-Xma-133868	Xiphophorus maculatus	40.91	8.00e-66	244.00
IUUC-Yli-134474	Yarrowia lipolytica	31.52	5.00e-15	75.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence