iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040201

Ensembl Protein ID

ENSGALP00000011677.6

UniProt Accession

E1C396; E1C396_CHICK

Genbank Protein ID

ENSGALP00000011677

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000355

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000007224.6	ENSGALT00000011691.6	ENSGALP00000011677.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	6.90e-51	172.1	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icd+i++ +++ak+a++a++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+e+lk+++e+ 
   Q: 15   ATSQLLLETDWESILQICDMIRQGDTQAKYAVNAIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKEILKRQVETS 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v+ K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRSKILNLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGRGGGTFER LLDKATSQLL LETDWESILQ ICDMIRQGDT QAKYAVNAIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKEILKRQV ETSVRSKILN LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGCAGCCG CTTCCCCAGC AGGCTCTTGC CGACGCCCGT CGCCCCCAGC AGCAGGCACG 60
TGGGCCCCGG CCGCGCAGCG CCCGCCATCC CCGCCCCGCC GGAAGCAGCG CGCGTCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

KEGG

gga:428675

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	76.97	0.00e+00	884.00
IUUC-Apl-003662	Anas platyrhynchos	90.31	0.00e+00	1060.00
IUUC-Aca-004940	Anolis carolinensis	85.91	0.00e+00	1193.00
IUUC-Ago-007931	Ashbya gossypii	31.73	6.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	34.43	1.00e-37	151.00
IUUC-Afl-008521	Aspergillus flavus	27.52	9.00e-41	161.00
IUUC-Afu-008774	Aspergillus fumigatus	35.85	1.00e-38	154.00
IUUC-Ani-009445	Aspergillus nidulans	31.85	4.00e-39	156.00
IUUC-Ang-009863	Aspergillus niger	32.36	2.00e-40	160.00
IUUC-Ate-010444	Aspergillus terreus	33.70	1.00e-40	160.00
IUUC-Ame-011111	Astyanax mexicanus	81.18	0.00e+00	948.00
IUUC-Bgr-012087	Blumeria graminis	32.97	6.00e-41	162.00
IUUC-Bta-012506	Bos taurus	83.81	0.00e+00	1068.00
IUUC-Bci-013782	Botrytis cinerea	36.15	1.00e-38	154.00
IUUC-Cel-018493	Caenorhabditis elegans	52.86	1.00e-68	254.00
IUUC-Cja-019998	Callithrix jacchus	79.16	0.00e+00	979.00
IUUC-Cfa-020615	Canis familiaris	80.36	0.00e+00	979.00
IUUC-Cpo-022019	Cavia porcellus	83.56	0.00e+00	1104.00
IUUC-Csa-023596	Chlorocebus sabaeus	80.67	0.00e+00	986.00
IUUC-Cin-025488	Ciona intestinalis	48.17	2.00e-127	449.00
IUUC-Csv-025802	Ciona savignyi	51.05	6.00e-116	410.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	37.09	3.00e-38	153.00
IUUC-Cne-026847	Cryptococcus neoformans	35.19	5.00e-38	152.00
IUUC-Dre-028353	Danio rerio	79.26	0.00e+00	946.00
IUUC-Dno-029005	Dasypus novemcinctus	80.72	0.00e+00	1049.00
IUUC-Dor-030280	Dipodomys ordii	81.67	0.00e+00	1044.00
IUUC-Dse-031238	Dothistroma septosporum	39.44	7.00e-43	168.00
IUUC-Dme-031952	Drosophila melanogaster	47.12	6.00e-99	354.00
IUUC-Ete-032235	Echinops telfairi	94.55	6.00e-130	457.00
IUUC-Eca-033873	Equus caballus	81.95	0.00e+00	1040.00
IUUC-Eeu-034652	Erinaceus europaeus	94.41	2.00e-103	369.00
IUUC-Fca-036563	Felis catus	80.15	0.00e+00	1016.00
IUUC-Fal-036649	Ficedula albicollis	95.09	0.00e+00	1160.00
IUUC-Fox-037962	Fusarium oxysporum	32.34	7.00e-38	152.00
IUUC-Fso-038396	Fusarium solani	32.97	3.00e-38	153.00
IUUC-Gmo-039510	Gadus morhua	75.29	0.00e+00	939.00
IUUC-Ggr-039938	Gaeumannomyces graminis	29.03	1.00e-36	147.00
IUUC-Gac-041459	Gasterosteus aculeatus	78.78	0.00e+00	970.00
IUUC-Ggo-044573	Gorilla gorilla	80.92	0.00e+00	1046.00
IUUC-Hsa-046009	Homo sapiens	81.18	0.00e+00	1092.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	80.92	0.00e+00	1115.00
IUUC-Kpa-049327	Komagataella pastoris	31.28	1.00e-33	138.00
IUUC-Lch-049944	Latimeria chalumnae	82.29	8.00e-170	589.00
IUUC-Loc-051850	Lepisosteus oculatus	83.10	0.00e+00	1048.00
IUUC-Lma-053252	Leptosphaeria maculans	36.15	6.00e-40	159.00
IUUC-Laf-053346	Loxodonta africana	75.19	0.00e+00	938.00
IUUC-Mcc-055789	Macaca mulatta	83.31	0.00e+00	1049.00
IUUC-Meu-056329	Macropus eugenii	68.05	5.00e-149	521.00
IUUC-Mor-057205	Magnaporthe oryzae	36.07	3.00e-37	149.00
IUUC-Mpo-057295	Magnaporthe poae	32.42	1.00e-38	154.00
IUUC-Mla-058849	Melampsora laricipopulina	32.87	3.00e-32	133.00
IUUC-Mga-059361	Meleagris gallopavo	96.48	0.00e+00	1204.00
IUUC-Mvi-060561	Microbotryum violaceum	36.44	2.00e-37	150.00
IUUC-Mmr-061122	Microcebus murinus	87.38	0.00e+00	931.00
IUUC-Mdo-062171	Monodelphis domestica	86.12	0.00e+00	1124.00
IUUC-Mmu-063952	Mus musculus	82.69	0.00e+00	1150.00
IUUC-Mpu-065852	Mustela putorius furo	80.56	0.00e+00	989.00
IUUC-Mlu-066996	Myotis lucifugus	70.46	9.00e-126	443.00
IUUC-Nfi-068539	Neosartorya fischeri	31.48	6.00e-39	155.00
IUUC-Ncr-068726	Neurospora crassa	38.50	6.00e-39	155.00
IUUC-Nle-070148	Nomascus leucogenys	76.50	0.00e+00	942.00
IUUC-Opr-070833	Ochotona princeps	63.44	8.00e-123	434.00
IUUC-Ont-071261	Oreochromis niloticus	79.75	0.00e+00	977.00
IUUC-Oan-073684	Ornithorhynchus anatinus	74.64	2.00e-158	551.00
IUUC-Ola-087570	Oryzias latipes	75.13	0.00e+00	967.00
IUUC-Oga-089087	Otolemur garnettii	80.47	0.00e+00	957.00
IUUC-Oar-089534	Ovis aries	83.67	0.00e+00	1071.00
IUUC-Ptr-091654	Pan troglodytes	76.31	0.00e+00	951.00
IUUC-Pan-092652	Papio anubis	81.05	0.00e+00	1049.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.61	4.00e-40	159.00
IUUC-Pfo-096757	Poecilia formosa	77.99	0.00e+00	935.00
IUUC-Pab-097788	Pongo abelii	86.38	0.00e+00	756.00
IUUC-Pca-100145	Procavia capensis	71.92	0.00e+00	830.00
IUUC-Pva-102965	Pteropus vampyrus	80.00	0.00e+00	998.00
IUUC-Pgr-103609	Puccinia graminis	34.18	7.00e-34	138.00
IUUC-Ptt-103865	Puccinia triticina	35.42	2.00e-34	140.00
IUUC-Pte-104095	Pyrenophora teres	35.32	5.00e-40	159.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.48	1.00e-39	158.00
IUUC-Rno-105125	Rattus norvegicus	84.14	0.00e+00	1063.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.83	3.00e-28	120.00
IUUC-Sha-107066	Sarcophilus harrisii	87.10	0.00e+00	1097.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.33	4.00e-40	159.00
IUUC-Spo-108220	Schizosaccharomyces pombe	36.87	6.00e-38	152.00
IUUC-Stu-112464	Solanum tuberosum	45.90	2.00e-13	71.20
IUUC-Sar-113393	Sorex araneus	91.05	5.00e-105	375.00
IUUC-Sre-114986	Sporisorium reilianum	39.01	3.00e-43	169.00
IUUC-Tgu-117505	Taeniopygia guttata	90.68	0.00e+00	1101.00
IUUC-Tru-118494	Takifugu rubripes	78.01	0.00e+00	994.00
IUUC-Tsy-119626	Tarsius syrichta	94.85	1.00e-52	200.00
IUUC-Tni-120174	Tetraodon nigroviridis	75.13	0.00e+00	997.00
IUUC-Tre-122191	Trichoderma reesei	33.09	5.00e-39	155.00
IUUC-Tvi-122318	Trichoderma virens	32.36	1.00e-38	154.00
IUUC-Tme-126914	Tuber melanosporum	34.05	2.00e-42	166.00
IUUC-Ttr-129095	Tursiops truncatus	84.37	0.00e+00	1094.00
IUUC-Uma-129475	Ustilago maydis	27.80	4.00e-39	156.00
IUUC-Vda-129908	Verticillium dahliae	34.11	1.00e-33	137.00
IUUC-Xtr-131900	Xenopus tropicalis	78.76	0.00e+00	1060.00
IUUC-Xma-133124	Xiphophorus maculatus	79.33	0.00e+00	976.00
IUUC-Yli-134682	Yarrowia lipolytica	34.39	2.00e-32	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence