iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033755

Ensembl Protein ID

ENSECAP00000002446.1

UniProt Accession

F6XMX1; F6XMX1_HORSE

Protein Name

Uncharacterized protein

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000003091.1	ENSECAT00000003450.1	ENSECAP00000002446.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.20e-55	189.1	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++cp+ +++ ++ke lve+el++rye+lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKE-LVEAELFARYERLLLQSTLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+++v++e+     ++  c++c+++fC+ C+ ++H  + Ck ++ekl + ++e+                        ee+eske
   Q: 309  CPRPCCQFPVMQEPG---CTMGiCPSCNFAFCTLCRLTYHGVSPCKVTAEKLIDLQNEYlqadeahkrfleqrygkrviqkalEEMESKE 395
           *************95...33337*********************************999******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C+++iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKSCPCCETPIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DGDEFRKAES VQGGETRIFL DLPQNFKIFV SGNSNECLPN 60
SGFEYTICFL PPLVLNFELP PDYPSSSPPS FTLSGKWLSP TQLSALCKHL DNLWEEHRGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATGGCAAG ATTTCTATAG TATATCTAGT ATGAGTTCCA CATCTTGGCC TCTTATCCAG 60
CTTCAGCAGT CTTCTCTTGA CCATCTGGAG AATAAATGGA ATTTCCATGA ATTCCAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0007165--P:signal transduction

KEGG

ecb:100061332

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	30.92	1.00e-52	201.00
IUUC-Aml-001458	Ailuropoda melanoleuca	95.31	0.00e+00	890.00
IUUC-Atr-002560	Amborella trichopoda	30.71	5.00e-46	179.00
IUUC-Apl-003680	Anas platyrhynchos	81.58	0.00e+00	759.00
IUUC-Aca-005000	Anolis carolinensis	71.00	0.00e+00	660.00
IUUC-Aly-006288	Arabidopsis lyrata	31.39	3.00e-53	202.00
IUUC-Ath-006719	Arabidopsis thaliana	31.17	8.00e-53	201.00
IUUC-Acl-008213	Aspergillus clavatus	25.49	2.00e-30	127.00
IUUC-Afl-008433	Aspergillus flavus	24.94	6.00e-31	129.00
IUUC-Afu-008772	Aspergillus fumigatus	25.27	3.00e-32	133.00
IUUC-Ani-009249	Aspergillus nidulans	25.00	3.00e-32	133.00
IUUC-Ang-009757	Aspergillus niger	28.61	7.00e-37	148.00
IUUC-Aor-009963	Aspergillus oryzae	24.78	2.00e-30	127.00
IUUC-Ate-010460	Aspergillus terreus	25.32	3.00e-31	129.00
IUUC-Ame-011312	Astyanax mexicanus	58.61	4.00e-144	504.00
IUUC-Bgr-012052	Blumeria graminis	23.06	9.00e-29	121.00
IUUC-Bta-013529	Bos taurus	95.50	0.00e+00	896.00
IUUC-Bci-013729	Botrytis cinerea	24.51	2.00e-26	114.00
IUUC-Bdi-014940	Brachypodium distachyon	32.17	6.00e-49	188.00
IUUC-Bra-016998	Brassica rapa	30.04	4.00e-49	189.00
IUUC-Cel-018547	Caenorhabditis elegans	30.54	3.00e-50	192.00
IUUC-Cja-019791	Callithrix jacchus	92.93	0.00e+00	878.00
IUUC-Cfa-020403	Canis familiaris	95.50	0.00e+00	899.00
IUUC-Cpo-022229	Cavia porcellus	89.98	0.00e+00	834.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	35.35	5.00e-31	127.00
IUUC-Csa-024115	Chlorocebus sabaeus	94.65	0.00e+00	891.00
IUUC-Cho-024911	Choloepus hoffmanni	95.29	0.00e+00	895.00
IUUC-Cin-025578	Ciona intestinalis	42.83	2.00e-99	356.00
IUUC-Csv-026355	Ciona savignyi	42.00	6.00e-87	314.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	22.85	2.00e-23	103.00
IUUC-Cne-026782	Cryptococcus neoformans	25.97	3.00e-31	129.00
IUUC-Dre-027380	Danio rerio	56.68	1.00e-151	529.00
IUUC-Dno-029640	Dasypus novemcinctus	95.09	0.00e+00	890.00
IUUC-Dor-030681	Dipodomys ordii	94.43	0.00e+00	890.00
IUUC-Dse-031208	Dothistroma septosporum	24.44	9.00e-31	128.00
IUUC-Ete-033122	Echinops telfairi	60.44	2.00e-131	462.00
IUUC-Eeu-035034	Erinaceus europaeus	96.58	8.00e-72	264.00
IUUC-Fca-036461	Felis catus	95.72	0.00e+00	899.00
IUUC-Fal-037516	Ficedula albicollis	80.82	0.00e+00	755.00
IUUC-Fso-038307	Fusarium solani	25.16	2.00e-24	107.00
IUUC-Gmo-039563	Gadus morhua	57.05	8.00e-147	513.00
IUUC-Ggr-039920	Gaeumannomyces graminis	23.49	1.00e-22	101.00
IUUC-Gga-040331	Gallus gallus	80.73	0.00e+00	744.00
IUUC-Gac-042164	Gasterosteus aculeatus	58.46	4.00e-154	537.00
IUUC-Gma-044080	Glycine max	32.33	2.00e-58	219.00
IUUC-Ggo-045257	Gorilla gorilla	94.00	0.00e+00	887.00
IUUC-Hsa-046887	Homo sapiens	94.57	0.00e+00	879.00
IUUC-Hvu-047317	Hordeum vulgare	29.84	3.00e-49	189.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	95.29	0.00e+00	897.00
IUUC-Lch-050155	Latimeria chalumnae	64.16	3.00e-164	571.00
IUUC-Lpe-051669	Leersia perrieri	30.52	1.00e-38	154.00
IUUC-Loc-051779	Lepisosteus oculatus	59.37	4.00e-153	534.00
IUUC-Lma-052969	Leptosphaeria maculans	24.30	4.00e-30	125.00
IUUC-Laf-053488	Loxodonta africana	92.72	0.00e+00	879.00
IUUC-Mcc-054701	Macaca mulatta	95.00	0.00e+00	881.00
IUUC-Meu-056577	Macropus eugenii	82.91	2.00e-125	442.00
IUUC-Mor-057157	Magnaporthe oryzae	22.50	3.00e-27	117.00
IUUC-Mpo-057518	Magnaporthe poae	22.37	7.00e-27	115.00
IUUC-Mtr-058125	Medicago truncatula	30.04	1.00e-47	184.00
IUUC-Mga-059906	Meleagris gallopavo	80.51	0.00e+00	740.00
IUUC-Mvi-060374	Microbotryum violaceum	33.00	2.00e-33	136.00
IUUC-Mmr-061786	Microcebus murinus	96.15	0.00e+00	900.00
IUUC-Mdo-062453	Monodelphis domestica	89.47	0.00e+00	819.00
IUUC-Mmu-063521	Mus musculus	90.02	0.00e+00	805.00
IUUC-Mac-065119	Musa acuminata	29.72	3.00e-40	159.00
IUUC-Mpu-066274	Mustela putorius furo	95.50	0.00e+00	896.00
IUUC-Mlu-067202	Myotis lucifugus	91.52	0.00e+00	834.00
IUUC-Nfi-068564	Neosartorya fischeri	24.29	4.00e-31	129.00
IUUC-Ncr-068823	Neurospora crassa	23.67	4.00e-29	123.00
IUUC-Nle-068987	Nomascus leucogenys	94.79	0.00e+00	882.00
IUUC-Opr-070453	Ochotona princeps	91.65	0.00e+00	858.00
IUUC-Ont-072611	Oreochromis niloticus	56.16	6.00e-153	533.00
IUUC-Oan-073738	Ornithorhynchus anatinus	81.30	0.00e+00	736.00
IUUC-Ocu-074396	Oryctolagus cuniculus	94.00	0.00e+00	883.00
IUUC-Oba-075472	Oryza barthii	31.87	6.00e-43	168.00
IUUC-Obr-076277	Oryza brachyantha	31.15	3.00e-45	176.00
IUUC-Ogl-077046	Oryza glaberrima	31.56	2.00e-41	164.00
IUUC-Ogu-078634	Oryza glumaepatula	31.87	3.00e-43	169.00
IUUC-Oin-080080	Oryza indica	29.39	8.00e-42	164.00
IUUC-Olo-080828	Oryza longistaminata	29.45	1.00e-40	162.00
IUUC-Ome-081387	Oryza meridionalis	30.63	4.00e-45	175.00
IUUC-Oni-082934	Oryza nivara	31.87	2.00e-43	170.00
IUUC-Opu-083719	Oryza punctata	30.21	4.00e-39	155.00
IUUC-Oru-084518	Oryza rufipogon	31.87	3.00e-43	169.00
IUUC-Ola-087312	Oryzias latipes	57.96	9.00e-152	530.00
IUUC-Olu-087661	Ostreococcus lucimarinus	28.76	1.00e-47	184.00
IUUC-Oga-089129	Otolemur garnettii	95.71	0.00e+00	898.00
IUUC-Oar-089839	Ovis aries	95.29	0.00e+00	895.00
IUUC-Ptr-091626	Pan troglodytes	94.78	0.00e+00	881.00
IUUC-Pan-092798	Papio anubis	95.00	0.00e+00	881.00
IUUC-Psi-093253	Pelodiscus sinensis	80.73	0.00e+00	764.00
IUUC-Pma-094512	Petromyzon marinus	55.60	2.00e-144	505.00
IUUC-Pno-094937	Phaeosphaeria nodorum	23.46	1.00e-27	117.00
IUUC-Ppa-095211	Physcomitrella patens	30.52	6.00e-53	202.00
IUUC-Pfo-097049	Poecilia formosa	52.92	2.00e-133	469.00
IUUC-Pab-097911	Pongo abelii	94.57	0.00e+00	879.00
IUUC-Pop-099841	Populus trichocarpa	31.06	1.00e-48	187.00
IUUC-Pca-100814	Procavia capensis	73.11	0.00e+00	640.00
IUUC-Ppe-101972	Prunus persica	30.77	4.00e-48	185.00
IUUC-Pva-103038	Pteropus vampyrus	95.07	0.00e+00	894.00
IUUC-Pgr-103277	Puccinia graminis	32.82	6.00e-39	154.00
IUUC-Ptt-103855	Puccinia triticina	30.74	1.00e-34	140.00
IUUC-Pte-104113	Pyrenophora teres	23.90	2.00e-27	116.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	23.44	3.00e-27	116.00
IUUC-Rno-106003	Rattus norvegicus	90.55	0.00e+00	812.00
IUUC-Sce-106287	Saccharomyces cerevisiae	27.91	2.00e-24	106.00
IUUC-Sha-106652	Sarcophilus harrisii	89.15	0.00e+00	827.00
IUUC-Spo-108167	Schizosaccharomyces pombe	30.87	4.00e-52	198.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	24.55	1.00e-08	55.50
IUUC-Smo-109393	Selaginella moellendorffii	31.64	3.00e-48	186.00
IUUC-Sit-110529	Setaria italica	33.68	1.00e-42	167.00
IUUC-Sly-111829	Solanum lycopersicum	31.49	7.00e-53	201.00
IUUC-Stu-112811	Solanum tuberosum	31.49	2.00e-53	204.00
IUUC-Sar-113259	Sorex araneus	90.65	2.00e-137	482.00
IUUC-Sbi-114591	Sorghum bicolor	31.66	3.00e-35	143.00
IUUC-Sre-115227	Sporisorium reilianum	26.45	3.00e-33	136.00
IUUC-Ssc-115293	Sus scrofa	93.79	0.00e+00	885.00
IUUC-Tgu-117335	Taeniopygia guttata	80.82	0.00e+00	747.00
IUUC-Tru-118458	Takifugu rubripes	56.56	1.00e-150	526.00
IUUC-Tsy-119475	Tarsius syrichta	86.94	0.00e+00	790.00
IUUC-Tni-119827	Tetraodon nigroviridis	56.25	7.00e-149	520.00
IUUC-Tca-121023	Theobroma cacao	32.16	7.00e-50	191.00
IUUC-Tre-121965	Trichoderma reesei	23.70	9.00e-31	127.00
IUUC-Tvi-122564	Trichoderma virens	21.32	1.00e-26	114.00
IUUC-Tae-124793	Triticum aestivum	33.70	1.00e-40	161.00
IUUC-Tur-126258	Triticum urartu	30.43	4.00e-44	172.00
IUUC-Tbe-127227	Tupaia belangeri	72.49	4.00e-73	268.00
IUUC-Ttr-128984	Tursiops truncatus	72.16	1.00e-176	612.00
IUUC-Uma-129565	Ustilago maydis	25.81	7.00e-32	132.00
IUUC-Vpa-130301	Vicugna pacos	96.15	0.00e+00	901.00
IUUC-Vvi-131244	Vitis vinifera	32.06	9.00e-52	198.00
IUUC-Xtr-132880	Xenopus tropicalis	59.66	5.00e-162	563.00
IUUC-Xma-134055	Xiphophorus maculatus	57.45	9.00e-154	536.00
IUUC-Yli-134342	Yarrowia lipolytica	28.88	6.00e-43	168.00
IUUC-Zma-135021	Zea mays	32.78	2.00e-38	154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence