iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-099423

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CM000340

Gene Name

POPTRDRAFT_800674; POPTR_0004s13540g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0004s13540	POPTR_0004s13540.1	POPTR_0004s13540.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	7.90e-76	256.7	2	325

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigN 97
           +w+++esdPg+ft+l+++  vk++ qveelysLd ++l+++ +pv+gl++lFk+ ++++ +r          vv  d   ++ffa qvi+N
   Q: 2    SWCTIESDPGVFTELIQQMHVKGV-QVEELYSLDLDSLDSL-RPVYGLVFLFKWRPEEKDER----------VVITDPNPNLFFARQVINN 80
           7***********************.****************.***************99999..........55668889*********** PP
   S: 98   sCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvning 188
           +Ca +A+ls l nc d   d+G++ls+lke+tk + pe k+la++n ++++++hns+ar +++  +e++++   +++++++hf+sy +++g
   Q: 81   ACASQAILSILMNCPDM--DIGPELSKLKEFTKNFPPELKGLAINNCEAIRAAHNSFARLGPFVPEEQKAA---SKEDDVYHFISYLPVDG 166
           ****************9..********************************************88777744...469************** PP
   S: 189  rlyeldglkpfPldlgkk...keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid................. 259
            lyeldglk+ P+ lg++   + + ++   ++ v+   eri+  ++ eirfnllaiv++r+ ++t+ l+ l+                   
   Q: 167  VLYELDGLKEGPISLGQCtggHGDMDWLLMVQPVI--QERIERHSNSEIRFNLLAIVKNRKEMYTAELKELQKRrerivqqlaafqaerlv 255
           *****************954445667777777777..*****************************9987666679*************** PP
   S: 260  .....keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklvee 324
                + L k l+++++ +e   +++  e+ek kk+  ++irR++ny  f++ f+k la++++l+ l e+
   Q: 256  dngnyESLNKSLSEVNAAIESATEKILMEEEKFKKWRTENIRRKHNYIPFLFNFLKILAEKKQLKPLIEK 325
           ****999**********************************************************99987 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQQM HVKGVQVEEL YSLDLDSLDS LRPVYGLVFL FKWRPEEKDE 60
RVVITDPNPN LFFARQVINN ACASQAILSI LMNCPDMDIG PELSKLKEFT KNFPPELKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGTAATT GCAAAGTGGA TTTGCTAGGC CGTTTAGTCT TCATCAAAAT CTTATTATGA 60
AGGAAAAAGA ATAATTAAAT GATTTAAATG TTTGTTCATT AGATCACAGT TCAGAAGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pop:POPTR_0004s13540g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003306	Anas platyrhynchos	45.13	6.00e-76	277.00
IUUC-Afl-008557	Aspergillus flavus	46.33	2.00e-53	202.00
IUUC-Aor-010145	Aspergillus oryzae	46.33	2.00e-53	202.00
IUUC-Ame-010791	Astyanax mexicanus	48.96	4.00e-85	307.00
IUUC-Bgr-012298	Blumeria graminis	39.88	7.00e-57	213.00
IUUC-Bta-013251	Bos taurus	48.16	2.00e-81	295.00
IUUC-Bci-013786	Botrytis cinerea	39.14	7.00e-56	210.00
IUUC-Cja-019768	Callithrix jacchus	44.63	1.00e-75	276.00
IUUC-Csa-023958	Chlorocebus sabaeus	48.16	4.00e-81	294.00
IUUC-Cin-025771	Ciona intestinalis	41.47	8.00e-63	233.00
IUUC-Csv-026149	Ciona savignyi	42.86	2.00e-66	245.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	36.14	7.00e-45	173.00
IUUC-Cme-027104	Cyanidioschyzon merolae	30.36	2.00e-45	175.00
IUUC-Dre-027409	Danio rerio	48.96	2.00e-85	308.00
IUUC-Dse-031170	Dothistroma septosporum	37.93	1.00e-52	199.00
IUUC-Eca-033776	Equus caballus	47.71	2.00e-72	265.00
IUUC-Fal-037597	Ficedula albicollis	47.06	4.00e-71	260.00
IUUC-Gmo-038499	Gadus morhua	44.48	4.00e-73	267.00
IUUC-Gga-040904	Gallus gallus	49.55	2.00e-85	308.00
IUUC-Gac-042058	Gasterosteus aculeatus	47.24	3.00e-80	291.00
IUUC-Hsa-046227	Homo sapiens	48.77	2.00e-81	295.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	44.54	7.00e-76	276.00
IUUC-Lch-049829	Latimeria chalumnae	47.85	1.00e-80	292.00
IUUC-Loc-052264	Lepisosteus oculatus	48.01	3.00e-79	288.00
IUUC-Lma-053110	Leptosphaeria maculans	49.12	7.00e-52	197.00
IUUC-Mcc-055506	Macaca mulatta	48.16	4.00e-81	294.00
IUUC-Mtr-057731	Medicago truncatula	86.23	2.00e-154	537.00
IUUC-Mga-060178	Meleagris gallopavo	48.58	1.00e-76	278.00
IUUC-Mvi-060353	Microbotryum violaceum	38.02	4.00e-52	197.00
IUUC-Mmu-063619	Mus musculus	49.09	8.00e-81	293.00
IUUC-Mpu-066058	Mustela putorius furo	48.47	8.00e-81	293.00
IUUC-Mlu-067292	Myotis lucifugus	48.47	5.00e-81	293.00
IUUC-Nfi-068275	Neosartorya fischeri	39.71	1.00e-56	212.00
IUUC-Nle-069013	Nomascus leucogenys	48.16	2.00e-81	295.00
IUUC-Ont-072688	Oreochromis niloticus	46.48	6.00e-80	290.00
IUUC-Oan-073004	Ornithorhynchus anatinus	50.68	9.00e-60	222.00
IUUC-Ocu-074303	Oryctolagus cuniculus	48.47	1.00e-80	293.00
IUUC-Ola-087126	Oryzias latipes	46.32	2.00e-79	288.00
IUUC-Oar-090296	Ovis aries	48.62	5.00e-80	290.00
IUUC-Ptr-090566	Pan troglodytes	48.77	2.00e-81	295.00
IUUC-Pan-092052	Papio anubis	48.16	4.00e-81	294.00
IUUC-Psi-093723	Pelodiscus sinensis	47.39	9.00e-73	266.00
IUUC-Ppa-095761	Physcomitrella patens	70.47	5.00e-133	466.00
IUUC-Pfo-096210	Poecilia formosa	47.85	2.00e-81	295.00
IUUC-Pca-100108	Procavia capensis	50.62	2.00e-65	241.00
IUUC-Pva-102629	Pteropus vampyrus	51.46	2.00e-67	248.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	47.81	3.00e-52	198.00
IUUC-Rno-105579	Rattus norvegicus	42.86	7.00e-69	253.00
IUUC-Sha-106894	Sarcophilus harrisii	48.43	4.00e-71	260.00
IUUC-Smo-109396	Selaginella moellendorffii	71.00	1.00e-129	455.00
IUUC-Sar-113294	Sorex araneus	42.90	5.00e-69	254.00
IUUC-Ssc-115501	Sus scrofa	47.00	3.00e-74	271.00
IUUC-Tgu-117152	Taeniopygia guttata	47.06	4.00e-71	260.00
IUUC-Tru-118388	Takifugu rubripes	47.55	4.00e-80	290.00
IUUC-Tni-120048	Tetraodon nigroviridis	47.55	3.00e-80	291.00
IUUC-Tre-122130	Trichoderma reesei	43.65	6.00e-52	197.00
IUUC-Tvi-122284	Trichoderma virens	44.84	8.00e-54	203.00
IUUC-Tbe-127619	Tupaia belangeri	42.81	3.00e-55	207.00
IUUC-Ttr-128867	Tursiops truncatus	44.72	2.00e-54	205.00
IUUC-Vda-129912	Verticillium dahliae	38.02	8.00e-53	200.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence