iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068184

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02024733

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012412.2	ENSMLUT00000012415.2	ENSMLUP00000011304.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-19	69.5	124	159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H d v+ ++   s+t  vsGs D  ikvWDl+++ +
   Q: 124  HDDIVCTVSVlrSGTQAVSGSKDFCIKVWDLTQQMV 159
           88999999977766*****************99865 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MRKETPPPLV PPEDREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGAAGG AAACCCCGCC CCCTCTAGTG CCCCCGGAGG ATCGCGAGTG GAACCTTCCC 60
CCTAATGCAC CCGCCTGTAT GGAGCGGCAG TTGGAGGCTG CGCGGTACCG GTCGGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.25	7.00e-179	619.00
IUUC-Apl-003921	Anas platyrhynchos	63.35	3.00e-66	243.00
IUUC-Aca-004870	Anolis carolinensis	69.90	2.00e-121	428.00
IUUC-Ame-011872	Astyanax mexicanus	47.78	3.00e-35	140.00
IUUC-Bta-013325	Bos taurus	93.00	0.00e+00	626.00
IUUC-Cja-019059	Callithrix jacchus	90.67	1.00e-176	612.00
IUUC-Cfa-021036	Canis familiaris	91.10	6.00e-155	540.00
IUUC-Cpo-022369	Cavia porcellus	89.50	2.00e-174	604.00
IUUC-Csa-023585	Chlorocebus sabaeus	90.67	6.00e-177	612.00
IUUC-Cho-024470	Choloepus hoffmanni	81.40	9.00e-112	395.00
IUUC-Dno-029867	Dasypus novemcinctus	89.21	3.00e-175	607.00
IUUC-Dor-030834	Dipodomys ordii	63.37	1.00e-110	392.00
IUUC-Ete-032245	Echinops telfairi	81.79	4.00e-136	477.00
IUUC-Eca-033360	Equus caballus	91.25	5.00e-172	596.00
IUUC-Eeu-035353	Erinaceus europaeus	88.63	6.00e-173	599.00
IUUC-Fca-036277	Felis catus	91.84	8.00e-179	619.00
IUUC-Fal-037383	Ficedula albicollis	68.60	1.00e-101	362.00
IUUC-Gmo-038575	Gadus morhua	53.89	9.00e-97	346.00
IUUC-Gga-040658	Gallus gallus	70.34	7.00e-129	453.00
IUUC-Gac-041463	Gasterosteus aculeatus	50.75	5.00e-83	301.00
IUUC-Ggo-045120	Gorilla gorilla	89.21	8.00e-175	605.00
IUUC-Hsa-046247	Homo sapiens	90.09	1.00e-175	608.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	89.50	4.00e-171	593.00
IUUC-Lch-049741	Latimeria chalumnae	66.14	1.00e-111	395.00
IUUC-Loc-052695	Lepisosteus oculatus	58.31	9.00e-105	373.00
IUUC-Laf-054535	Loxodonta africana	88.83	3.00e-174	604.00
IUUC-Mcc-054699	Macaca mulatta	90.67	6.00e-177	612.00
IUUC-Meu-056053	Macropus eugenii	74.42	6.00e-134	469.00
IUUC-Mga-059672	Meleagris gallopavo	65.13	1.00e-71	261.00
IUUC-Mmr-060963	Microcebus murinus	91.84	2.00e-179	621.00
IUUC-Mdo-062694	Monodelphis domestica	72.67	1.00e-128	452.00
IUUC-Mmu-064031	Mus musculus	87.17	1.00e-170	592.00
IUUC-Mpu-066408	Mustela putorius furo	92.13	3.00e-179	620.00
IUUC-Nle-069251	Nomascus leucogenys	90.38	8.00e-177	612.00
IUUC-Opr-071156	Ochotona princeps	82.51	7.00e-159	553.00
IUUC-Ont-072683	Oreochromis niloticus	56.31	1.00e-94	339.00
IUUC-Oan-073042	Ornithorhynchus anatinus	74.49	1.00e-124	439.00
IUUC-Ocu-074843	Oryctolagus cuniculus	91.25	6.00e-174	602.00
IUUC-Ola-086929	Oryzias latipes	52.60	3.00e-87	315.00
IUUC-Oga-088237	Otolemur garnettii	89.50	5.00e-175	606.00
IUUC-Oar-089312	Ovis aries	93.38	4.00e-166	576.00
IUUC-Ptr-091625	Pan troglodytes	89.50	7.00e-175	606.00
IUUC-Pan-091902	Papio anubis	89.91	5.00e-166	576.00
IUUC-Psi-094035	Pelodiscus sinensis	72.30	3.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	62.98	1.00e-56	211.00
IUUC-Pfo-097070	Poecilia formosa	53.31	3.00e-90	325.00
IUUC-Pab-098007	Pongo abelii	90.09	4.00e-176	610.00
IUUC-Pca-100513	Procavia capensis	73.03	9.00e-101	359.00
IUUC-Pva-102821	Pteropus vampyrus	87.17	7.00e-166	576.00
IUUC-Rno-105836	Rattus norvegicus	86.82	1.00e-172	598.00
IUUC-Sha-106847	Sarcophilus harrisii	68.92	3.00e-88	318.00
IUUC-Sar-113451	Sorex araneus	86.34	6.00e-168	583.00
IUUC-Ssc-115978	Sus scrofa	90.38	2.00e-171	595.00
IUUC-Tgu-116745	Taeniopygia guttata	69.43	3.00e-94	337.00
IUUC-Tru-117945	Takifugu rubripes	54.49	2.00e-80	292.00
IUUC-Tsy-119059	Tarsius syrichta	85.39	3.00e-86	310.00
IUUC-Tni-120414	Tetraodon nigroviridis	55.56	3.00e-94	338.00
IUUC-Tbe-127559	Tupaia belangeri	92.13	1.00e-179	622.00
IUUC-Ttr-128505	Tursiops truncatus	91.84	8.00e-177	612.00
IUUC-Vpa-130350	Vicugna pacos	92.35	3.00e-98	350.00
IUUC-Xtr-132939	Xenopus tropicalis	61.64	7.00e-111	393.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence