iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073406

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01213875

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002495.2	ENSOANT00000003947.2	ENSOANP00000003946.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.30e-06	27.6	61	88
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.80e-10	39.3	160	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFya 28
           +Dv+l+v+ +ef +h++vLaa+S +F+ 
   Q: 61   TDVVLCVDIKEFACHRVVLAAASNYFRY 88
           7*************************86 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eNc+gilr+Ad++++++Lk++++ +i+++F
   Q: 160  PENCVGILRLADTHSLDHLKKQVQGYIIQNF 190
           89***************************** PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGDTVEKSSE EPLAPFDDES SGESGDLVEI SNGDKVKFDD TGLSLILQKG LENLRVENSL 60
TDVVLCVDIK EFACHRVVLA AASNYFRYCS TRNLKTVLKS NILIMHLSVH SQHTLLLHVY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGACA CAGTAGAAAA AAGTTCAGAA GAACCCTTAG CTCCCTTTGA TGATGAGAGT 60
TCCGGGGAAA GCGGGGATCT GGTTGAAATC TCGAATGGTG ACAAGGTGAA ATTTGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	84.26	0.00e+00	1076.00
IUUC-Apl-003490	Anas platyrhynchos	79.84	0.00e+00	1039.00
IUUC-Aca-005136	Anolis carolinensis	78.64	0.00e+00	983.00
IUUC-Ame-010886	Astyanax mexicanus	63.09	0.00e+00	755.00
IUUC-Bta-013473	Bos taurus	83.11	0.00e+00	1035.00
IUUC-Cja-018888	Callithrix jacchus	83.44	0.00e+00	1069.00
IUUC-Cpo-021761	Cavia porcellus	80.62	0.00e+00	1009.00
IUUC-Csa-023206	Chlorocebus sabaeus	83.77	0.00e+00	1074.00
IUUC-Cin-025367	Ciona intestinalis	36.64	3.00e-114	404.00
IUUC-Csv-026076	Ciona savignyi	37.03	2.00e-107	382.00
IUUC-Dre-027948	Danio rerio	67.65	0.00e+00	822.00
IUUC-Dno-030045	Dasypus novemcinctus	83.61	0.00e+00	1067.00
IUUC-Dor-030839	Dipodomys ordii	76.56	0.00e+00	950.00
IUUC-Eca-033608	Equus caballus	83.93	0.00e+00	1046.00
IUUC-Eeu-034640	Erinaceus europaeus	82.46	0.00e+00	1052.00
IUUC-Fca-036065	Felis catus	83.61	0.00e+00	1071.00
IUUC-Fal-036949	Ficedula albicollis	79.50	0.00e+00	1013.00
IUUC-Gmo-039661	Gadus morhua	53.22	2.00e-156	544.00
IUUC-Gga-040740	Gallus gallus	79.02	0.00e+00	1025.00
IUUC-Gac-042413	Gasterosteus aculeatus	56.72	0.00e+00	709.00
IUUC-Ggo-045167	Gorilla gorilla	83.77	0.00e+00	1075.00
IUUC-Hsa-046120	Homo sapiens	83.77	0.00e+00	1075.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	83.11	0.00e+00	1063.00
IUUC-Lch-049709	Latimeria chalumnae	75.37	0.00e+00	971.00
IUUC-Loc-052239	Lepisosteus oculatus	73.28	0.00e+00	900.00
IUUC-Laf-054511	Loxodonta africana	83.11	0.00e+00	1064.00
IUUC-Mcc-055109	Macaca mulatta	83.77	0.00e+00	1073.00
IUUC-Meu-056522	Macropus eugenii	73.53	5.00e-102	364.00
IUUC-Mga-060012	Meleagris gallopavo	77.58	0.00e+00	997.00
IUUC-Mmr-061364	Microcebus murinus	83.28	0.00e+00	1064.00
IUUC-Mdo-063033	Monodelphis domestica	76.62	0.00e+00	947.00
IUUC-Mmu-063880	Mus musculus	81.80	0.00e+00	1019.00
IUUC-Mlu-068233	Myotis lucifugus	83.61	0.00e+00	1048.00
IUUC-Opr-070638	Ochotona princeps	81.09	0.00e+00	736.00
IUUC-Ont-071960	Oreochromis niloticus	57.45	0.00e+00	716.00
IUUC-Ocu-074612	Oryctolagus cuniculus	83.55	0.00e+00	1068.00
IUUC-Ola-087181	Oryzias latipes	55.72	0.00e+00	703.00
IUUC-Oga-088955	Otolemur garnettii	83.61	0.00e+00	1066.00
IUUC-Oar-089682	Ovis aries	83.28	0.00e+00	1035.00
IUUC-Ptr-090969	Pan troglodytes	83.77	0.00e+00	1075.00
IUUC-Pan-092289	Papio anubis	83.77	0.00e+00	1074.00
IUUC-Psi-093279	Pelodiscus sinensis	81.15	0.00e+00	1051.00
IUUC-Pab-097957	Pongo abelii	83.11	0.00e+00	801.00
IUUC-Pca-100619	Procavia capensis	81.31	0.00e+00	1053.00
IUUC-Pva-102533	Pteropus vampyrus	77.90	6.00e-168	583.00
IUUC-Rno-106111	Rattus norvegicus	81.80	0.00e+00	1045.00
IUUC-Sha-106716	Sarcophilus harrisii	83.28	0.00e+00	1056.00
IUUC-Tgu-116839	Taeniopygia guttata	79.67	0.00e+00	1033.00
IUUC-Tru-117792	Takifugu rubripes	56.64	0.00e+00	690.00
IUUC-Tsy-119609	Tarsius syrichta	73.63	2.00e-122	432.00
IUUC-Tni-119682	Tetraodon nigroviridis	55.85	0.00e+00	688.00
IUUC-Tbe-127961	Tupaia belangeri	77.38	0.00e+00	950.00
IUUC-Ttr-128917	Tursiops truncatus	81.96	0.00e+00	870.00
IUUC-Vpa-130721	Vicugna pacos	83.25	0.00e+00	730.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence