iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000000850.2	ENSCJAT00000001551.2	ENSCJAP00000001461.2
ENSCJAG00000000850.2	ENSCJAT00000001552.2	ENSCJAP00000001462.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.80e-25	90.3	21	126

Active Site

Position(s)	Description	Evidence
98	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.e 88
           Rl+ke++el kdp+++++a+p ++ +l+ew++++ Gp+d+ ++ggv++ +i +p++YP+kPP++ +lt   ++ ++   k+Clsi + +
   Q: 21   RLMKEAAEL-KDPTDHYHAQPLED-NLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTA--NGRFEVGKKICLSISGhH 105
           9*******9.99************.9******************************************9..9999999********549 PP
   S: 89   eekWspalsvesvllsiqsll 109
           +e+W+p +s+++ ll+i+ ++
   Q: 106  PETWQPSWSIRTALLAIIGFM 126
           ******************998 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

EPGQRPAMET RYNLKSPAVK RLMKEAAELK DPTDHYHAQP LEDNLFEWHF TVRGPPDSDF 60
DGGVYHGRIV LPPEYPMKPP SIILLTANGR FEVGKKICLS ISGHHPETWQ PSWSIRTALL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCAGAGA GCAAAGGAGG TGGCAGTGGC TAAAGGAGAG CCCCAGAGGA CAACTGCATC 60
CACAGATTGA TGGACCTGGA GGCTGAATAG CAAAAGGCTT CTAGTACTCC CCTATCAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1904153--P:negative regulation of retrograde protein transport, ER to cytosol
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0042534--P:regulation of tumor necrosis factor biosynthetic process
GO:0007286--P:spermatid development
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	34.12	4.00e-35	142.00
IUUC-Aml-002404	Ailuropoda melanoleuca	95.28	3.00e-153	534.00
IUUC-Atr-002806	Amborella trichopoda	63.70	2.00e-55	209.00
IUUC-Apl-003507	Anas platyrhynchos	77.42	5.00e-123	433.00
IUUC-Aca-004697	Anolis carolinensis	75.23	3.00e-111	394.00
IUUC-Aly-005556	Arabidopsis lyrata	61.81	2.00e-54	205.00
IUUC-Ath-007477	Arabidopsis thaliana	61.11	4.00e-54	204.00
IUUC-Acl-008101	Aspergillus clavatus	56.46	1.00e-46	179.00
IUUC-Afl-008466	Aspergillus flavus	56.13	3.00e-45	175.00
IUUC-Afu-009109	Aspergillus fumigatus	53.46	9.00e-41	160.00
IUUC-Ani-009343	Aspergillus nidulans	53.85	2.00e-42	166.00
IUUC-Ang-009509	Aspergillus niger	57.94	5.00e-41	159.00
IUUC-Aor-010210	Aspergillus oryzae	56.13	3.00e-45	175.00
IUUC-Ate-010571	Aspergillus terreus	49.35	3.00e-39	156.00
IUUC-Ame-010806	Astyanax mexicanus	81.35	8.00e-88	317.00
IUUC-Bgr-012063	Blumeria graminis	45.96	2.00e-50	192.00
IUUC-Bta-012638	Bos taurus	93.67	4.00e-148	516.00
IUUC-Bci-013709	Botrytis cinerea	51.38	3.00e-49	188.00
IUUC-Bdi-014694	Brachypodium distachyon	60.42	8.00e-52	197.00
IUUC-Bol-015399	Brassica oleracea	60.27	9.00e-54	203.00
IUUC-Bra-017645	Brassica rapa	60.27	8.00e-54	203.00
IUUC-Cel-018452	Caenorhabditis elegans	61.70	7.00e-70	257.00
IUUC-Cfa-020218	Canis familiaris	95.13	1.00e-145	508.00
IUUC-Cpo-022552	Cavia porcellus	94.65	7.00e-158	549.00
IUUC-Cre-022888	Chlamydomonas reinhardtii	60.14	3.00e-54	203.00
IUUC-Csa-024028	Chlorocebus sabaeus	96.86	7.00e-155	539.00
IUUC-Cho-024606	Choloepus hoffmanni	69.81	2.00e-96	345.00
IUUC-Cin-025631	Ciona intestinalis	62.79	1.00e-78	286.00
IUUC-Csv-026321	Ciona savignyi	70.27	1.00e-76	279.00
IUUC-Cgl-026755	Colletotrichum gloeosporioides	47.34	1.00e-49	189.00
IUUC-Cne-026839	Cryptococcus neoformans	50.31	4.00e-41	161.00
IUUC-Cme-027189	Cyanidioschyzon merolae	59.12	2.00e-45	176.00
IUUC-Dre-027569	Danio rerio	83.51	4.00e-92	330.00
IUUC-Dno-029214	Dasypus novemcinctus	94.65	1.00e-151	528.00
IUUC-Dor-030145	Dipodomys ordii	66.11	4.00e-55	207.00
IUUC-Dse-031537	Dothistroma septosporum	46.31	5.00e-52	197.00
IUUC-Ete-033083	Echinops telfairi	91.51	2.00e-140	491.00
IUUC-Eca-034179	Equus caballus	94.16	3.00e-150	523.00
IUUC-Eeu-035115	Erinaceus europaeus	78.93	2.00e-113	401.00
IUUC-Fca-036083	Felis catus	96.23	4.00e-155	540.00
IUUC-Fal-037289	Ficedula albicollis	75.74	4.00e-112	397.00
IUUC-Fox-038027	Fusarium oxysporum	58.04	9.00e-41	159.00
IUUC-Fso-038254	Fusarium solani	52.53	1.00e-50	193.00
IUUC-Ggr-039884	Gaeumannomyces graminis	55.92	5.00e-50	191.00
IUUC-Gga-041156	Gallus gallus	75.48	7.00e-123	433.00
IUUC-Gac-041807	Gasterosteus aculeatus	48.21	7.00e-39	154.00
IUUC-Gma-044356	Glycine max	63.27	1.00e-56	213.00
IUUC-Ggo-044450	Gorilla gorilla	98.11	1.00e-158	551.00
IUUC-Hsa-046496	Homo sapiens	97.80	4.00e-158	550.00
IUUC-Hvu-047328	Hordeum vulgare	59.72	3.00e-51	194.00
IUUC-Itr-048629	Ictidomys tridecemlineatus	96.54	8.00e-156	542.00
IUUC-Lch-050348	Latimeria chalumnae	68.11	8.00e-109	386.00
IUUC-Lpe-050862	Leersia perrieri	60.42	3.00e-52	198.00
IUUC-Loc-052465	Lepisosteus oculatus	60.90	3.00e-88	318.00
IUUC-Lma-053257	Leptosphaeria maculans	51.08	3.00e-53	201.00
IUUC-Laf-053830	Loxodonta africana	94.65	2.00e-155	541.00
IUUC-Mcc-054880	Macaca mulatta	96.86	1.00e-155	542.00
IUUC-Mor-057183	Magnaporthe oryzae	50.91	1.00e-49	189.00
IUUC-Mpo-057391	Magnaporthe poae	55.63	1.00e-50	192.00
IUUC-Mtr-058479	Medicago truncatula	61.90	6.00e-56	210.00
IUUC-Mga-059321	Meleagris gallopavo	74.19	8.00e-118	416.00
IUUC-Mvi-060366	Microbotryum violaceum	59.48	1.00e-50	193.00
IUUC-Mmr-061717	Microcebus murinus	96.74	3.00e-148	517.00
IUUC-Mdo-061865	Monodelphis domestica	83.80	1.00e-123	436.00
IUUC-Mmu-064049	Mus musculus	91.82	9.00e-146	509.00
IUUC-Mac-064669	Musa acuminata	58.90	2.00e-52	199.00
IUUC-Mpu-066177	Mustela putorius furo	95.05	2.00e-143	501.00
IUUC-Mlu-067037	Myotis lucifugus	92.86	6.00e-143	499.00
IUUC-Nfi-068283	Neosartorya fischeri	46.35	4.00e-43	168.00
IUUC-Ncr-068645	Neurospora crassa	46.29	2.00e-49	189.00
IUUC-Nle-069166	Nomascus leucogenys	98.11	5.00e-158	550.00
IUUC-Opr-070562	Ochotona princeps	100.00	6.00e-20	91.30
IUUC-Ont-072096	Oreochromis niloticus	66.98	1.00e-107	382.00
IUUC-Oan-073369	Ornithorhynchus anatinus	78.62	3.00e-111	394.00
IUUC-Ocu-074815	Oryctolagus cuniculus	93.71	3.00e-151	527.00
IUUC-Oba-075649	Oryza barthii	60.42	2.00e-52	198.00
IUUC-Obr-076169	Oryza brachyantha	60.14	4.00e-53	201.00
IUUC-Ogl-077144	Oryza glaberrima	60.42	2.00e-52	198.00
IUUC-Ogu-078255	Oryza glumaepatula	60.42	3.00e-52	198.00
IUUC-Oin-079510	Oryza indica	61.11	3.00e-51	195.00
IUUC-Olo-080589	Oryza longistaminata	47.03	6.00e-46	177.00
IUUC-Ome-081849	Oryza meridionalis	55.41	2.00e-49	189.00
IUUC-Oni-082959	Oryza nivara	60.42	3.00e-52	198.00
IUUC-Opu-083736	Oryza punctata	60.69	4.00e-52	198.00
IUUC-Oru-084215	Oryza rufipogon	60.42	3.00e-52	198.00
IUUC-Osa-085722	Oryza sativa	60.42	3.00e-52	198.00
IUUC-Ola-086717	Oryzias latipes	82.97	9.00e-93	333.00
IUUC-Olu-087750	Ostreococcus lucimarinus	66.06	2.00e-41	160.00
IUUC-Oga-088848	Otolemur garnettii	83.65	3.00e-126	444.00
IUUC-Oar-090134	Ovis aries	94.81	2.00e-146	511.00
IUUC-Ptr-091314	Pan troglodytes	98.11	1.00e-158	551.00
IUUC-Pan-092103	Papio anubis	97.17	2.00e-155	541.00
IUUC-Psi-093668	Pelodiscus sinensis	81.51	6.00e-110	389.00
IUUC-Pno-094982	Phaeosphaeria nodorum	56.38	4.00e-49	187.00
IUUC-Ppa-095836	Physcomitrella patens	62.11	2.00e-59	222.00
IUUC-Pfo-096964	Poecilia formosa	62.69	1.00e-101	362.00
IUUC-Pab-097857	Pongo abelii	96.86	3.00e-156	543.00
IUUC-Pop-099025	Populus trichocarpa	63.01	4.00e-56	211.00
IUUC-Pca-101108	Procavia capensis	92.47	8.00e-101	359.00
IUUC-Ppe-101444	Prunus persica	61.38	1.00e-54	206.00
IUUC-Pva-102297	Pteropus vampyrus	83.07	1.00e-119	422.00
IUUC-Pte-104112	Pyrenophora teres	54.27	3.00e-52	198.00
IUUC-Pyt-104824	Pyrenophora triticirepentis	56.06	4.00e-44	171.00
IUUC-Rno-105336	Rattus norvegicus	97.18	5.00e-123	433.00
IUUC-Sha-107324	Sarcophilus harrisii	85.31	9.00e-129	452.00
IUUC-Smo-109549	Selaginella moellendorffii	68.75	1.00e-60	226.00
IUUC-Sit-110794	Setaria italica	59.46	7.00e-52	197.00
IUUC-Sly-111585	Solanum lycopersicum	64.19	2.00e-57	215.00
IUUC-Stu-111996	Solanum tuberosum	64.19	4.00e-57	214.00
IUUC-Sar-113063	Sorex araneus	92.18	1.00e-140	491.00
IUUC-Sbi-114593	Sorghum bicolor	59.46	6.00e-52	197.00
IUUC-Sre-115043	Sporisorium reilianum	52.20	4.00e-51	195.00
IUUC-Ssc-115523	Sus scrofa	95.28	7.00e-147	513.00
IUUC-Tgu-116966	Taeniopygia guttata	72.98	4.00e-121	427.00
IUUC-Tru-117737	Takifugu rubripes	62.92	9.00e-101	359.00
IUUC-Tsy-119190	Tarsius syrichta	100.00	4.00e-62	231.00
IUUC-Tni-120283	Tetraodon nigroviridis	94.59	6.00e-41	157.00
IUUC-Tca-120992	Theobroma cacao	64.38	2.00e-56	212.00
IUUC-Tre-122028	Trichoderma reesei	53.85	1.00e-49	189.00
IUUC-Tvi-122637	Trichoderma virens	54.04	6.00e-51	194.00
IUUC-Tae-122793	Triticum aestivum	59.72	2.00e-51	195.00
IUUC-Tme-126962	Tuber melanosporum	41.74	1.00e-51	196.00
IUUC-Tbe-127743	Tupaia belangeri	95.44	5.00e-146	509.00
IUUC-Ttr-129193	Tursiops truncatus	93.49	9.00e-144	502.00
IUUC-Uma-129586	Ustilago maydis	47.22	1.00e-50	193.00
IUUC-Vda-129959	Verticillium dahliae	54.43	1.00e-50	193.00
IUUC-Vpa-130404	Vicugna pacos	95.44	3.00e-146	510.00
IUUC-Vvi-130893	Vitis vinifera	62.33	2.00e-55	209.00
IUUC-Xtr-131832	Xenopus tropicalis	71.15	5.00e-104	370.00
IUUC-Zma-135443	Zea mays	59.46	3.00e-52	198.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence