iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035389

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02105381

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000026080.1	ENSFCAT00000022864.1	ENSFCAP00000025372.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.80e-15	54.7	358	405
E3 adaptor/Cullin RING/DCX/DWD	4.70e-32	108.7	153	186
UBD/Beta-Prp	5.80e-46	157.0	127	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+a r++l+++++    +LP+Pk++k++L y++
   Q: 358  HVQFWTAPRVLSSLKHLCRKALRSFLTTYQV---LALPIPKKMKEFLTYRT 405
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           gH+d v++l+f  s+  +lvs+s+D+t+++WDl 
   Q: 153  GHQDVVRDLSFtpSGsLILVSASRDKTLRIWDLN 186
           8***********6556779*************85 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklv 110
           +latg  dg ik+w+v+tg ll  lsgh++ v++++f p+g+ ilv++s+D+t+++wdl+  gk++++l+gh + v+++s+sp+ + l 
   Q: 127  ILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSlILVSASRDKTLRIWDLNkHGKQIQVLSGHLQWVYCCSVSPDCSMLC 215
           79****************************************9****************9789********************99**** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...........tgghtdsvyslsf 188
           s+   + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D+ v +Wd  tg+ lr l           +  h +s +s+ f
   Q: 216  SAAGEKSVFLWSMRSYTLIR-KLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLhhtqldppmddSDVHISSLRSVCF 303
           ********************.********************************************9999**99999778999999999* PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++g +l+++++d+ +++w l+ ++   +  +  +n ++  f+p++  +++g+ Dg +++W
   Q: 304  SPEGLYLATVADDRLLRIWALELKT--PIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 362
           *********************9885..7899****************************** PP

Organism

Felis catus

Protein Sequence
(Fasta)

MLSPVLEEPL LLAELKPGRP HQFDWKSSCE TWSVAFSPDG SWFAWSQGHC IVKLIPWPLE 60
EHFIPKGFEA KSRSSKNDTK GRGSPKEKTL DCGQIVWGLA FSPWPSPPSR KLWARHHPQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGTCTC CCGTCTTAGA GGAACCGCTG CTGCTGGCTG AGCTCAAGCC CGGGCGTCCC 60
CACCAGTTCG ATTGGAAGTC GAGCTGCGAA ACCTGGAGCG TGGCCTTCTC CCCAGATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

fca:101092549

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	99.26	0.00e+00	825.00
IUUC-Apl-004107	Anas platyrhynchos	68.50	9.00e-131	459.00
IUUC-Aca-004354	Anolis carolinensis	73.48	2.00e-165	575.00
IUUC-Bta-012627	Bos taurus	98.03	0.00e+00	776.00
IUUC-Cja-018897	Callithrix jacchus	96.40	0.00e+00	775.00
IUUC-Cfa-020122	Canis familiaris	99.01	0.00e+00	825.00
IUUC-Cpo-022540	Cavia porcellus	97.04	0.00e+00	788.00
IUUC-Csa-023719	Chlorocebus sabaeus	97.94	0.00e+00	787.00
IUUC-Cho-024367	Choloepus hoffmanni	97.65	7.00e-173	599.00
IUUC-Dno-029021	Dasypus novemcinctus	98.03	0.00e+00	796.00
IUUC-Dor-030321	Dipodomys ordii	97.42	0.00e+00	782.00
IUUC-Ete-032955	Echinops telfairi	97.44	0.00e+00	768.00
IUUC-Eca-033485	Equus caballus	98.72	0.00e+00	769.00
IUUC-Fal-037184	Ficedula albicollis	84.10	2.00e-142	497.00
IUUC-Gga-041014	Gallus gallus	76.94	5.00e-171	593.00
IUUC-Ggo-045585	Gorilla gorilla	98.21	0.00e+00	797.00
IUUC-Hsa-046344	Homo sapiens	97.78	0.00e+00	795.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	98.20	0.00e+00	791.00
IUUC-Lch-050131	Latimeria chalumnae	69.87	1.00e-162	566.00
IUUC-Loc-052807	Lepisosteus oculatus	54.74	1.00e-113	403.00
IUUC-Laf-053528	Loxodonta africana	97.54	0.00e+00	771.00
IUUC-Mcc-055665	Macaca mulatta	97.78	0.00e+00	795.00
IUUC-Meu-056054	Macropus eugenii	87.92	0.00e+00	686.00
IUUC-Mga-059326	Meleagris gallopavo	77.44	3.00e-179	620.00
IUUC-Mmr-060815	Microcebus murinus	96.06	0.00e+00	780.00
IUUC-Mdo-062000	Monodelphis domestica	91.07	0.00e+00	734.00
IUUC-Mmu-063927	Mus musculus	96.14	0.00e+00	778.00
IUUC-Mpu-065726	Mustela putorius furo	97.17	0.00e+00	779.00
IUUC-Mlu-067527	Myotis lucifugus	97.14	3.00e-119	420.00
IUUC-Nle-069680	Nomascus leucogenys	98.21	0.00e+00	788.00
IUUC-Opr-070356	Ochotona princeps	97.95	0.00e+00	789.00
IUUC-Oan-073647	Ornithorhynchus anatinus	84.31	9.00e-136	476.00
IUUC-Ocu-073973	Oryctolagus cuniculus	97.04	0.00e+00	785.00
IUUC-Oga-088797	Otolemur garnettii	97.30	0.00e+00	786.00
IUUC-Oar-089187	Ovis aries	98.47	0.00e+00	777.00
IUUC-Ptr-091317	Pan troglodytes	98.21	0.00e+00	796.00
IUUC-Pan-092694	Papio anubis	90.13	0.00e+00	677.00
IUUC-Psi-093392	Pelodiscus sinensis	79.34	0.00e+00	632.00
IUUC-Pab-098145	Pongo abelii	97.94	0.00e+00	786.00
IUUC-Pca-100454	Procavia capensis	89.00	0.00e+00	708.00
IUUC-Pva-102986	Pteropus vampyrus	90.28	0.00e+00	712.00
IUUC-Rno-104931	Rattus norvegicus	95.10	0.00e+00	769.00
IUUC-Sha-106476	Sarcophilus harrisii	92.09	0.00e+00	732.00
IUUC-Ssc-115643	Sus scrofa	98.97	0.00e+00	793.00
IUUC-Tgu-117522	Taeniopygia guttata	63.04	4.00e-130	457.00
IUUC-Tsy-119301	Tarsius syrichta	98.25	0.00e+00	810.00
IUUC-Ttr-128683	Tursiops truncatus	98.97	0.00e+00	793.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence