iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025413

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01001776

Gene Name

socs6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000009026.3	ENSCINT00000018328.3	ENSCINP00000018328.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.40e-12	47.1	362	404

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            ++ s++r+Lq+LCR++Ir++++++++   + LPLP+  k YL + 
   Q: 362  VSRLSQVRTLQYLCRFVIRQYTRIDHI---ESLPLPNPVKGYLNES 404
           57899*******************998...*************875 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MKRFRNLSVN KRKKHLDTAV PEIDNVEPQS KDDNVPINQK AKFKFRIGKT LFRTKSAKKS 60
SSSNESERNS TIAENKNGPS SSLTDVQSNQ DSPIQVNNSN FLNDSTQERS CQTDELSNGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTTACAA ATAGATTACA GCCTGGTGTT GTCTGTACAC AAAGTTTTGC ATAAATTAAT 60
AAAACTTGCC CCACTGTTGA AAATCAAAGT AAAGCAAATC AGCGGTTATG AAAAGATTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	68.24	8.00e-56	209.00
IUUC-Apl-004035	Anas platyrhynchos	68.24	7.00e-56	210.00
IUUC-Aca-004782	Anolis carolinensis	68.82	3.00e-56	211.00
IUUC-Aly-005790	Arabidopsis lyrata	24.39	8.40e-01	26.90
IUUC-Ath-007174	Arabidopsis thaliana	26.62	3.70e-02	31.60
IUUC-Ame-011135	Astyanax mexicanus	67.06	5.00e-55	207.00
IUUC-Bta-012579	Bos taurus	69.28	2.00e-55	208.00
IUUC-Cel-018643	Caenorhabditis elegans	32.81	1.00e-10	57.80
IUUC-Cja-019528	Callithrix jacchus	68.24	5.00e-56	210.00
IUUC-Cfa-020678	Canis familiaris	68.24	5.00e-56	210.00
IUUC-Cpo-021947	Cavia porcellus	68.24	4.00e-56	211.00
IUUC-Csa-023935	Chlorocebus sabaeus	68.24	6.00e-56	210.00
IUUC-Cho-024477	Choloepus hoffmanni	66.47	3.00e-53	201.00
IUUC-Csv-026247	Ciona savignyi	55.56	3.00e-115	407.00
IUUC-Dre-027636	Danio rerio	67.65	3.00e-55	207.00
IUUC-Dno-029048	Dasypus novemcinctus	68.24	7.00e-56	210.00
IUUC-Dor-030401	Dipodomys ordii	68.24	7.00e-56	210.00
IUUC-Dme-031876	Drosophila melanogaster	40.36	7.00e-30	124.00
IUUC-Ete-033023	Echinops telfairi	34.66	4.00e-23	99.80
IUUC-Eca-033825	Equus caballus	68.82	1.00e-56	212.00
IUUC-Eeu-035208	Erinaceus europaeus	34.87	1.00e-20	92.80
IUUC-Fca-036253	Felis catus	68.24	1.00e-55	209.00
IUUC-Fal-037614	Ficedula albicollis	68.24	8.00e-56	209.00
IUUC-Gmo-038928	Gadus morhua	67.06	5.00e-54	203.00
IUUC-Gga-040177	Gallus gallus	68.24	7.00e-56	210.00
IUUC-Gac-042263	Gasterosteus aculeatus	67.06	2.00e-53	202.00
IUUC-Ggo-045288	Gorilla gorilla	68.24	5.00e-56	210.00
IUUC-Hsa-046409	Homo sapiens	68.24	5.00e-56	210.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	68.24	1.00e-55	209.00
IUUC-Lch-050354	Latimeria chalumnae	68.24	5.00e-56	210.00
IUUC-Loc-052319	Lepisosteus oculatus	67.06	4.00e-55	207.00
IUUC-Laf-054070	Loxodonta africana	68.24	7.00e-56	209.00
IUUC-Mcc-055045	Macaca mulatta	68.24	6.00e-56	210.00
IUUC-Meu-055917	Macropus eugenii	68.24	5.00e-56	210.00
IUUC-Mga-059273	Meleagris gallopavo	68.24	8.00e-56	209.00
IUUC-Mmr-061597	Microcebus murinus	68.24	6.00e-56	210.00
IUUC-Mdo-061892	Monodelphis domestica	47.02	5.00e-42	164.00
IUUC-Mmu-063374	Mus musculus	68.24	8.00e-56	209.00
IUUC-Mpu-065967	Mustela putorius furo	68.24	9.00e-56	209.00
IUUC-Mlu-067532	Myotis lucifugus	68.24	7.00e-56	210.00
IUUC-Nle-069373	Nomascus leucogenys	67.84	4.00e-56	211.00
IUUC-Opr-070873	Ochotona princeps	67.65	1.00e-65	242.00
IUUC-Ont-072498	Oreochromis niloticus	66.47	9.00e-54	203.00
IUUC-Oan-073443	Ornithorhynchus anatinus	34.34	4.00e-21	92.80
IUUC-Ocu-073870	Oryctolagus cuniculus	68.24	6.00e-56	210.00
IUUC-Ola-086866	Oryzias latipes	66.47	5.00e-53	199.00
IUUC-Oga-089057	Otolemur garnettii	68.24	7.00e-56	210.00
IUUC-Oar-090013	Ovis aries	69.28	1.00e-55	209.00
IUUC-Ptr-091054	Pan troglodytes	68.24	6.00e-56	210.00
IUUC-Pan-092064	Papio anubis	47.02	3.00e-42	165.00
IUUC-Psi-093834	Pelodiscus sinensis	45.60	2.00e-42	164.00
IUUC-Pma-094253	Petromyzon marinus	68.90	4.00e-62	230.00
IUUC-Pfo-097179	Poecilia formosa	67.06	9.00e-54	203.00
IUUC-Pab-097702	Pongo abelii	68.24	5.00e-56	210.00
IUUC-Pca-100671	Procavia capensis	69.62	3.00e-52	198.00
IUUC-Pva-102784	Pteropus vampyrus	47.02	4.00e-42	164.00
IUUC-Ptt-103775	Puccinia triticina	42.11	7.90e-01	27.70
IUUC-Rno-106044	Rattus norvegicus	68.24	9.00e-56	209.00
IUUC-Sha-107139	Sarcophilus harrisii	66.92	1.00e-37	149.00
IUUC-Sar-112975	Sorex araneus	44.14	4.00e-23	100.00
IUUC-Ssc-115343	Sus scrofa	68.24	6.00e-56	210.00
IUUC-Tgu-117061	Taeniopygia guttata	68.24	7.00e-56	210.00
IUUC-Tru-117562	Takifugu rubripes	46.20	1.00e-40	159.00
IUUC-Tsy-118999	Tarsius syrichta	50.00	1.00e-33	135.00
IUUC-Tni-119829	Tetraodon nigroviridis	66.47	2.00e-53	202.00
IUUC-Tbe-127671	Tupaia belangeri	47.02	3.00e-42	164.00
IUUC-Ttr-129148	Tursiops truncatus	68.82	9.00e-56	209.00
IUUC-Vpa-130780	Vicugna pacos	68.24	1.00e-55	209.00
IUUC-Xtr-132513	Xenopus tropicalis	66.47	1.00e-53	202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence