iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053612

Ensembl Protein ID

ENSLAFP00000015402.3

UniProt Accession

G3TKN8; G3TKN8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

MALT1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018379.3	ENSLAFT00000018380.3	ENSLAFP00000015402.3
ENSLAFG00000018379.3	ENSLAFT00000033911.1	ENSLAFP00000025502.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	89.45	0.00e+00	1459.00	IUUC-Hsa-046966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSLWGEPLQA PPPSASHPPL TAPAGPPPPP PASATLNRLR EPLLRRLSET LDRAPEGRGW 60
RRLAEVAGSR GRLRLSCLDL EQCSLKVLEP EGSPSLCLLK LMGEKGCTVT ELSDFLQAME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCTCT GGGGGGAGCC GCTGCAGGCC CCGCCACCCT CGGCCTCGCA CCCGCCCCTG 60
ACCGCGCCCG CAGGGCCGCC GCCACCCCCT CCGGCCAGCG CGACCCTCAA CCGCCTACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029030--Caspase-like_dom
IPR011029--DEATH-like_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR033540--MALT1
IPR001309--Pept_C14_p20

PROSITE

PS50208--CASPASE_P20
PS50835--IG_LIKE

Pfam

PF13895--Ig_2

SMART

SM00409--IG
SM00408--IGc2

Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0019209--F:kinase activator activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0001923--P:B-1 B cell differentiation
GO:0045087--P:innate immune response
GO:0051168--P:nuclear export
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032743--P:positive regulation of interleukin-2 production
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0050870--P:positive regulation of T cell activation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0051259--P:protein oligomerization
GO:0042981--P:regulation of apoptotic process
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0009620--P:response to fungus
GO:0002237--P:response to molecule of bacterial origin
GO:0042098--P:T cell proliferation
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003814	Anas platyrhynchos	69.80	0.00e+00	1067.00
IUUC-Aca-005192	Anolis carolinensis	62.13	0.00e+00	738.00
IUUC-Aly-005742	Arabidopsis lyrata	32.89	7.00e-03	34.70
IUUC-Ame-010608	Astyanax mexicanus	54.81	0.00e+00	793.00
IUUC-Bta-012436	Bos taurus	88.68	0.00e+00	1394.00
IUUC-Cel-018688	Caenorhabditis elegans	27.26	3.00e-44	173.00
IUUC-Cja-018945	Callithrix jacchus	78.82	0.00e+00	1196.00
IUUC-Cfa-020245	Canis familiaris	89.88	0.00e+00	1391.00
IUUC-Cpo-022400	Cavia porcellus	87.61	0.00e+00	1401.00
IUUC-Csa-023556	Chlorocebus sabaeus	90.04	0.00e+00	1313.00
IUUC-Cho-024489	Choloepus hoffmanni	82.52	7.00e-161	561.00
IUUC-Csv-026274	Ciona savignyi	32.09	3.00e-08	52.00
IUUC-Dre-028666	Danio rerio	53.12	0.00e+00	754.00
IUUC-Dno-029397	Dasypus novemcinctus	90.27	0.00e+00	1434.00
IUUC-Ete-032600	Echinops telfairi	92.55	6.00e-86	311.00
IUUC-Eca-033475	Equus caballus	90.00	0.00e+00	1385.00
IUUC-Eeu-034788	Erinaceus europaeus	85.59	0.00e+00	1347.00
IUUC-Fca-035687	Felis catus	88.17	0.00e+00	1382.00
IUUC-Fal-037432	Ficedula albicollis	66.40	0.00e+00	989.00
IUUC-Gmo-038533	Gadus morhua	53.01	0.00e+00	684.00
IUUC-Gga-040429	Gallus gallus	69.43	0.00e+00	1085.00
IUUC-Gac-041963	Gasterosteus aculeatus	57.31	0.00e+00	807.00
IUUC-Ggo-045328	Gorilla gorilla	90.29	0.00e+00	1407.00
IUUC-Hsa-046966	Homo sapiens	90.80	0.00e+00	1415.00
IUUC-Itr-048424	Ictidomys tridecemlineatus	92.18	0.00e+00	895.00
IUUC-Lch-049486	Latimeria chalumnae	66.20	0.00e+00	979.00
IUUC-Loc-051782	Lepisosteus oculatus	58.84	0.00e+00	870.00
IUUC-Mcc-054811	Macaca mulatta	88.31	0.00e+00	1373.00
IUUC-Meu-056602	Macropus eugenii	89.77	1.00e-129	456.00
IUUC-Mmr-060713	Microcebus murinus	89.03	0.00e+00	1460.00
IUUC-Mdo-062385	Monodelphis domestica	78.76	0.00e+00	1246.00
IUUC-Mpu-065996	Mustela putorius furo	88.55	0.00e+00	1288.00
IUUC-Mlu-067627	Myotis lucifugus	87.66	0.00e+00	1334.00
IUUC-Nle-069583	Nomascus leucogenys	90.42	0.00e+00	1410.00
IUUC-Opr-070641	Ochotona princeps	85.22	0.00e+00	1000.00
IUUC-Ont-071363	Oreochromis niloticus	58.08	0.00e+00	797.00
IUUC-Oan-073407	Ornithorhynchus anatinus	80.86	0.00e+00	743.00
IUUC-Ola-086554	Oryzias latipes	58.71	0.00e+00	771.00
IUUC-Oga-088538	Otolemur garnettii	82.99	0.00e+00	1259.00
IUUC-Oar-090012	Ovis aries	88.43	0.00e+00	1327.00
IUUC-Ptr-090677	Pan troglodytes	90.68	0.00e+00	1414.00
IUUC-Pan-092262	Papio anubis	90.34	0.00e+00	1416.00
IUUC-Psi-093186	Pelodiscus sinensis	68.79	0.00e+00	1006.00
IUUC-Pfo-097154	Poecilia formosa	57.12	0.00e+00	775.00
IUUC-Pab-098695	Pongo abelii	84.29	0.00e+00	1286.00
IUUC-Pca-100956	Procavia capensis	96.39	0.00e+00	766.00
IUUC-Pva-102917	Pteropus vampyrus	80.75	0.00e+00	823.00
IUUC-Rno-105680	Rattus norvegicus	86.07	0.00e+00	1282.00
IUUC-Sha-107559	Sarcophilus harrisii	82.15	0.00e+00	1252.00
IUUC-Sar-113054	Sorex araneus	81.84	0.00e+00	749.00
IUUC-Ssc-116110	Sus scrofa	86.52	0.00e+00	1305.00
IUUC-Tgu-116542	Taeniopygia guttata	73.30	0.00e+00	1012.00
IUUC-Tru-118019	Takifugu rubripes	56.39	0.00e+00	760.00
IUUC-Tsy-119591	Tarsius syrichta	82.59	0.00e+00	946.00
IUUC-Tbe-128075	Tupaia belangeri	62.75	6.00e-117	414.00
IUUC-Ttr-128309	Tursiops truncatus	83.00	0.00e+00	1228.00
IUUC-Vpa-130271	Vicugna pacos	88.95	0.00e+00	922.00
IUUC-Xtr-132554	Xenopus tropicalis	62.26	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence