iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062269

Ensembl Protein ID

ENSMODP00000000980.2

UniProt Accession

F6S901; F6S901_MONDO

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000824.2	ENSMODT00000000999.2	ENSMODP00000000980.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	4.20e-83	278.2	47	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s+kk+ ++f++Y++p+e ++g eg+ekfced+gv+pe+i++Lvlawklea+++++f++ee+l+g+t+l+cd++eklq k+++l+s+l+d
   Q: 47   SSKKCLAWFYEYAGPDE-VVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSKFDFLRSQLND 134
           78*************95.*********************************************************************** PP
   S: 91   eqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPv 179
           +++fk+iYr+af+fa+dk+q+sld+dta+++++Lll +r+++l+++++++Le++k+++++kD+W+++Lefs+++++dlsnYde+gaWPv
   Q: 135  ISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLL-GRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPV 222
           ************************************.999************************************************* PP
   S: 180  liDefveylk 189
           l+Defve++k
   Q: 223  LLDEFVEWQK 232
           ********86 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPVKKKRKSS GAAAAVAEDG GLKKCKISSY CRSQVPAKLI SGEEHFSSKK CLAWFYEYAG 60
PDEVVGPEGM EKFCEDIGVE PENIIMLVLA WKLEAESMGF FTKEEWLKGM TSLQCDCTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCTCTT CTTCTTCCTC TTCCTCCTCT CTCCGGGGAG CGGGGGCCAG CGCTGAGGGG 60
CCGCCCGCGC ACGGCTTCCC CTCTCCCGGC CGGCTCCGCT CCCCTGCCCG CCCCGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

mdo:100011186

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001567	Ailuropoda melanoleuca	97.05	2.00e-137	481.00
IUUC-Apl-003338	Anas platyrhynchos	88.61	9.00e-125	439.00
IUUC-Aca-004660	Anolis carolinensis	91.56	3.00e-129	453.00
IUUC-Afu-009005	Aspergillus fumigatus	31.07	2.00e-17	81.60
IUUC-Bta-013463	Bos taurus	96.62	3.00e-135	473.00
IUUC-Cja-019665	Callithrix jacchus	97.47	1.00e-137	481.00
IUUC-Cfa-020873	Canis familiaris	96.20	2.00e-136	477.00
IUUC-Csa-023661	Chlorocebus sabaeus	97.47	1.00e-137	481.00
IUUC-Cin-025635	Ciona intestinalis	56.71	2.00e-52	197.00
IUUC-Csv-025976	Ciona savignyi	49.19	8.00e-63	233.00
IUUC-Cme-027199	Cyanidioschyzon merolae	23.31	6.00e-08	51.20
IUUC-Dre-028080	Danio rerio	78.39	2.00e-112	398.00
IUUC-Dno-029984	Dasypus novemcinctus	96.23	1.00e-135	476.00
IUUC-Dor-030556	Dipodomys ordii	95.78	9.00e-135	472.00
IUUC-Eca-034108	Equus caballus	97.47	1.00e-137	481.00
IUUC-Fca-035374	Felis catus	89.41	2.00e-123	434.00
IUUC-Fal-037284	Ficedula albicollis	95.31	1.00e-120	424.00
IUUC-Gga-040330	Gallus gallus	93.67	1.00e-131	461.00
IUUC-Gac-042443	Gasterosteus aculeatus	75.32	6.00e-102	363.00
IUUC-Ggo-044892	Gorilla gorilla	97.47	1.00e-137	481.00
IUUC-Hsa-046320	Homo sapiens	97.47	1.00e-137	481.00
IUUC-Itr-048437	Ictidomys tridecemlineatus	98.44	2.00e-72	263.00
IUUC-Lch-049750	Latimeria chalumnae	87.76	7.00e-124	436.00
IUUC-Loc-052941	Lepisosteus oculatus	84.39	5.00e-120	423.00
IUUC-Laf-054402	Loxodonta africana	97.05	5.00e-137	479.00
IUUC-Mcc-055269	Macaca mulatta	97.47	1.00e-137	481.00
IUUC-Meu-056847	Macropus eugenii	85.84	1.00e-108	385.00
IUUC-Mga-059420	Meleagris gallopavo	95.28	5.00e-119	419.00
IUUC-Mmr-061732	Microcebus murinus	97.05	3.00e-137	480.00
IUUC-Mmu-063396	Mus musculus	96.24	3.00e-122	430.00
IUUC-Mpu-066206	Mustela putorius furo	98.21	6.00e-97	345.00
IUUC-Mlu-067871	Myotis lucifugus	97.89	1.00e-138	484.00
IUUC-Nfi-068610	Neosartorya fischeri	31.64	3.00e-18	84.30
IUUC-Nle-069808	Nomascus leucogenys	97.47	1.00e-137	481.00
IUUC-Opr-070404	Ochotona princeps	96.46	3.00e-61	228.00
IUUC-Ont-072416	Oreochromis niloticus	70.39	2.00e-97	347.00
IUUC-Oan-072930	Ornithorhynchus anatinus	86.55	5.00e-120	423.00
IUUC-Ocu-073767	Oryctolagus cuniculus	97.47	4.00e-138	483.00
IUUC-Ola-086378	Oryzias latipes	69.33	1.00e-97	348.00
IUUC-Oga-088583	Otolemur garnettii	97.47	1.00e-137	481.00
IUUC-Oar-089612	Ovis aries	96.65	3.00e-121	426.00
IUUC-Ptr-090753	Pan troglodytes	97.47	1.00e-137	481.00
IUUC-Pan-091951	Papio anubis	97.47	1.00e-137	481.00
IUUC-Psi-093385	Pelodiscus sinensis	95.45	2.00e-125	441.00
IUUC-Pma-094582	Petromyzon marinus	71.73	6.00e-99	353.00
IUUC-Pfo-096222	Poecilia formosa	70.12	6.00e-97	346.00
IUUC-Pab-097692	Pongo abelii	97.47	1.00e-137	481.00
IUUC-Pop-098821	Populus trichocarpa	46.60	2.00e-23	100.00
IUUC-Pva-102620	Pteropus vampyrus	97.72	1.00e-126	445.00
IUUC-Rno-105023	Rattus norvegicus	96.71	8.00e-123	432.00
IUUC-Sha-107177	Sarcophilus harrisii	100.00	6.00e-131	459.00
IUUC-Sar-113656	Sorex araneus	85.58	3.00e-101	360.00
IUUC-Ssc-116272	Sus scrofa	97.47	2.00e-137	481.00
IUUC-Tgu-116631	Taeniopygia guttata	93.15	4.00e-119	420.00
IUUC-Tsy-119350	Tarsius syrichta	96.62	1.00e-136	478.00
IUUC-Tbe-127515	Tupaia belangeri	90.68	4.00e-125	439.00
IUUC-Ttr-128784	Tursiops truncatus	73.42	2.00e-92	331.00
IUUC-Vpa-130543	Vicugna pacos	97.05	2.00e-137	481.00
IUUC-Xtr-132448	Xenopus tropicalis	88.94	2.00e-125	441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence