iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020199

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03001363

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005519.3	ENSCAFT00000008896.3	ENSCAFP00000008252.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-24	84.2	367	399
UBD/Beta-Prp	2.00e-44	152.3	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           gHtd vt+  f  ++ +vsGsdD t+kvWDlr 
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLRN 399
           8*******99*733669*************986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLFDVETAELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLRNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************998874555555.55555555559*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpmCNLFTCGFDRQAIGWSIN 488
           *********9999777899******99999985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MPTESGTCSA ARQAKQKRKS HSLSIRRTNS SEQERTALPR EMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIETLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATGTGGC TACTAGAAAA TTTGCCGTTG TGTGTGTGGT TTGTATTGCA TTTCTCTTGG 60
ACAGCATTGC TGTGAGGCTA GGACATGTGA TTAGACTCTG TTCTCTCTGG GGAGGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

cfa:607652

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	98.59	0.00e+00	981.00
IUUC-Apl-003647	Anas platyrhynchos	91.73	0.00e+00	923.00
IUUC-Aca-004759	Anolis carolinensis	91.33	0.00e+00	934.00
IUUC-Ame-011103	Astyanax mexicanus	55.75	8.00e-143	500.00
IUUC-Bta-012718	Bos taurus	95.36	0.00e+00	956.00
IUUC-Cel-018499	Caenorhabditis elegans	42.54	9.00e-96	343.00
IUUC-Cja-019492	Callithrix jacchus	95.16	0.00e+00	982.00
IUUC-Cpo-022500	Cavia porcellus	89.52	0.00e+00	931.00
IUUC-Csa-023567	Chlorocebus sabaeus	95.77	0.00e+00	988.00
IUUC-Cho-025071	Choloepus hoffmanni	67.54	0.00e+00	637.00
IUUC-Cin-025460	Ciona intestinalis	44.54	2.00e-103	369.00
IUUC-Csv-026042	Ciona savignyi	46.21	2.00e-109	389.00
IUUC-Dre-028214	Danio rerio	81.45	0.00e+00	851.00
IUUC-Dno-029826	Dasypus novemcinctus	94.46	0.00e+00	816.00
IUUC-Dor-030967	Dipodomys ordii	94.92	0.00e+00	885.00
IUUC-Dme-031936	Drosophila melanogaster	50.00	1.00e-119	423.00
IUUC-Ete-032452	Echinops telfairi	91.73	0.00e+00	939.00
IUUC-Eca-033278	Equus caballus	96.17	0.00e+00	996.00
IUUC-Eeu-034592	Erinaceus europaeus	82.86	0.00e+00	827.00
IUUC-Fca-036431	Felis catus	98.59	0.00e+00	1011.00
IUUC-Fal-037149	Ficedula albicollis	90.93	0.00e+00	918.00
IUUC-Gmo-038476	Gadus morhua	76.80	0.00e+00	760.00
IUUC-Gga-041099	Gallus gallus	91.73	0.00e+00	924.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.00	0.00e+00	819.00
IUUC-Ggo-044683	Gorilla gorilla	87.50	0.00e+00	893.00
IUUC-Hsa-046658	Homo sapiens	94.96	0.00e+00	981.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	96.26	0.00e+00	920.00
IUUC-Lch-050571	Latimeria chalumnae	83.11	0.00e+00	865.00
IUUC-Loc-052652	Lepisosteus oculatus	80.92	0.00e+00	851.00
IUUC-Laf-053712	Loxodonta africana	94.99	0.00e+00	974.00
IUUC-Mcc-055521	Macaca mulatta	95.77	0.00e+00	988.00
IUUC-Meu-056324	Macropus eugenii	87.90	0.00e+00	878.00
IUUC-Mga-060114	Meleagris gallopavo	91.94	0.00e+00	931.00
IUUC-Mmr-061176	Microcebus murinus	95.36	0.00e+00	981.00
IUUC-Mdo-061888	Monodelphis domestica	92.74	0.00e+00	917.00
IUUC-Mmu-063977	Mus musculus	94.96	0.00e+00	991.00
IUUC-Mpu-066220	Mustela putorius furo	85.56	0.00e+00	646.00
IUUC-Mlu-068155	Myotis lucifugus	96.37	0.00e+00	998.00
IUUC-Nle-069964	Nomascus leucogenys	95.16	0.00e+00	983.00
IUUC-Opr-070925	Ochotona princeps	94.20	2.00e-149	521.00
IUUC-Ont-071317	Oreochromis niloticus	85.28	0.00e+00	838.00
IUUC-Oan-072952	Ornithorhynchus anatinus	93.15	0.00e+00	944.00
IUUC-Ocu-073913	Oryctolagus cuniculus	95.97	0.00e+00	995.00
IUUC-Ola-087024	Oryzias latipes	83.70	0.00e+00	876.00
IUUC-Oga-087945	Otolemur garnettii	94.76	0.00e+00	987.00
IUUC-Oar-089854	Ovis aries	95.56	0.00e+00	947.00
IUUC-Ptr-091486	Pan troglodytes	95.16	0.00e+00	983.00
IUUC-Pan-091738	Papio anubis	95.77	0.00e+00	988.00
IUUC-Psi-093953	Pelodiscus sinensis	91.13	0.00e+00	924.00
IUUC-Pma-094560	Petromyzon marinus	73.07	0.00e+00	763.00
IUUC-Pfo-097222	Poecilia formosa	83.67	0.00e+00	825.00
IUUC-Pab-098778	Pongo abelii	90.52	0.00e+00	922.00
IUUC-Pca-100852	Procavia capensis	90.93	0.00e+00	918.00
IUUC-Pva-103130	Pteropus vampyrus	95.87	2.00e-135	475.00
IUUC-Rno-105848	Rattus norvegicus	85.89	0.00e+00	874.00
IUUC-Sha-106750	Sarcophilus harrisii	93.15	0.00e+00	947.00
IUUC-Sar-113749	Sorex araneus	86.69	0.00e+00	878.00
IUUC-Ssc-115691	Sus scrofa	94.15	0.00e+00	939.00
IUUC-Tgu-117365	Taeniopygia guttata	90.32	0.00e+00	873.00
IUUC-Tru-117595	Takifugu rubripes	82.66	0.00e+00	823.00
IUUC-Tsy-118973	Tarsius syrichta	74.45	3.00e-151	528.00
IUUC-Tni-120545	Tetraodon nigroviridis	82.53	0.00e+00	860.00
IUUC-Tbe-127976	Tupaia belangeri	70.77	0.00e+00	686.00
IUUC-Ttr-128472	Tursiops truncatus	92.74	0.00e+00	948.00
IUUC-Xtr-132621	Xenopus tropicalis	89.72	0.00e+00	890.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence