iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061888

UUCD1 version

UUC-MoD-00555

Ensembl Protein ID

ENSMODP00000007871.2

UniProt Accession

F7AFM6; F7AFM6_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000006325.3	ENSMODT00000008030.3	ENSMODP00000007871.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-23	80.7	367	398
UBD/Beta-Prp	1.70e-45	155.6	277	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vht 89
           +tlk+h+  vi   ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +
   Q: 277  TTLKSHQGVVIA-ADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNV 364
           667776665555.99999999***********************************************************665422889 PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtl 175
           ++gh+d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  
   Q: 365  FQGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSN 451
           **********99999.********************988874555555.55555555559*****************777778888888 PP
   S: 176  tgghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
           ++gh ++v + +++++     l +++ d++ + w++ 
   Q: 452  RQGHRRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           888*************9777899***********986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPTESGSCAT ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQTIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCAAATC ACAGTACACC TACTCATCTC ATCATTGGTG AGATTCATGG AAAAGAAACC 60
CTTTCAAAAC AGCTTGGATC TTAAGCTTTG GAAACTGATT AAATAGCTAT GAACAGTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

mdo:100017400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	93.35	0.00e+00	949.00
IUUC-Apl-003647	Anas platyrhynchos	95.16	0.00e+00	952.00
IUUC-Aca-004759	Anolis carolinensis	95.16	0.00e+00	967.00
IUUC-Ame-011103	Astyanax mexicanus	56.15	3.00e-145	508.00
IUUC-Bta-012718	Bos taurus	92.54	0.00e+00	943.00
IUUC-Cel-018499	Caenorhabditis elegans	41.78	7.00e-96	344.00
IUUC-Cja-019492	Callithrix jacchus	94.15	0.00e+00	972.00
IUUC-Cfa-020199	Canis familiaris	92.74	0.00e+00	967.00
IUUC-Cpo-022500	Cavia porcellus	88.51	0.00e+00	922.00
IUUC-Csa-023567	Chlorocebus sabaeus	94.96	0.00e+00	978.00
IUUC-Cho-025071	Choloepus hoffmanni	67.74	0.00e+00	639.00
IUUC-Cin-025460	Ciona intestinalis	45.51	7.00e-105	374.00
IUUC-Csv-026042	Ciona savignyi	46.21	6.00e-108	384.00
IUUC-Dre-028214	Danio rerio	83.87	0.00e+00	874.00
IUUC-Dno-029826	Dasypus novemcinctus	95.90	0.00e+00	830.00
IUUC-Dor-030967	Dipodomys ordii	94.48	0.00e+00	879.00
IUUC-Dme-031936	Drosophila melanogaster	48.52	6.00e-117	414.00
IUUC-Ete-032452	Echinops telfairi	92.34	0.00e+00	951.00
IUUC-Eca-033278	Equus caballus	93.15	0.00e+00	969.00
IUUC-Eeu-034592	Erinaceus europaeus	81.65	0.00e+00	814.00
IUUC-Fca-036431	Felis catus	93.56	0.00e+00	972.00
IUUC-Fal-037149	Ficedula albicollis	93.75	0.00e+00	944.00
IUUC-Gmo-038476	Gadus morhua	81.52	0.00e+00	783.00
IUUC-Gga-041099	Gallus gallus	94.76	0.00e+00	952.00
IUUC-Gac-042374	Gasterosteus aculeatus	86.20	0.00e+00	841.00
IUUC-Ggo-044683	Gorilla gorilla	86.69	0.00e+00	884.00
IUUC-Hsa-046658	Homo sapiens	94.15	0.00e+00	972.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.16	0.00e+00	907.00
IUUC-Lch-050571	Latimeria chalumnae	86.15	0.00e+00	900.00
IUUC-Loc-052652	Lepisosteus oculatus	83.40	0.00e+00	876.00
IUUC-Laf-053712	Loxodonta africana	93.99	0.00e+00	972.00
IUUC-Mcc-055521	Macaca mulatta	94.96	0.00e+00	978.00
IUUC-Meu-056324	Macropus eugenii	93.75	0.00e+00	919.00
IUUC-Mga-060114	Meleagris gallopavo	94.96	0.00e+00	959.00
IUUC-Mmr-061176	Microcebus murinus	94.35	0.00e+00	972.00
IUUC-Mmu-063977	Mus musculus	95.16	0.00e+00	988.00
IUUC-Mpu-066220	Mustela putorius furo	80.21	5.00e-175	607.00
IUUC-Mlu-068155	Myotis lucifugus	93.55	0.00e+00	973.00
IUUC-Nle-069964	Nomascus leucogenys	94.35	0.00e+00	974.00
IUUC-Opr-070925	Ochotona princeps	90.94	1.00e-144	506.00
IUUC-Ont-071317	Oreochromis niloticus	87.90	0.00e+00	867.00
IUUC-Oan-072952	Ornithorhynchus anatinus	96.98	0.00e+00	974.00
IUUC-Ocu-073913	Oryctolagus cuniculus	94.96	0.00e+00	985.00
IUUC-Ola-087024	Oryzias latipes	85.51	0.00e+00	892.00
IUUC-Oga-087945	Otolemur garnettii	93.75	0.00e+00	979.00
IUUC-Oar-089854	Ovis aries	92.94	0.00e+00	938.00
IUUC-Ptr-091486	Pan troglodytes	94.35	0.00e+00	973.00
IUUC-Pan-091738	Papio anubis	94.96	0.00e+00	978.00
IUUC-Psi-093953	Pelodiscus sinensis	95.56	0.00e+00	964.00
IUUC-Pma-094560	Petromyzon marinus	74.65	0.00e+00	779.00
IUUC-Pfo-097222	Poecilia formosa	84.27	0.00e+00	837.00
IUUC-Pab-098778	Pongo abelii	89.92	0.00e+00	914.00
IUUC-Pca-100852	Procavia capensis	90.93	0.00e+00	923.00
IUUC-Pva-103130	Pteropus vampyrus	92.98	7.00e-133	467.00
IUUC-Rno-105848	Rattus norvegicus	85.89	0.00e+00	869.00
IUUC-Sha-106750	Sarcophilus harrisii	98.79	0.00e+00	986.00
IUUC-Sar-113749	Sorex araneus	84.88	0.00e+00	859.00
IUUC-Ssc-115691	Sus scrofa	91.33	0.00e+00	921.00
IUUC-Tgu-117365	Taeniopygia guttata	93.55	0.00e+00	899.00
IUUC-Tru-117595	Takifugu rubripes	86.09	0.00e+00	850.00
IUUC-Tsy-118973	Tarsius syrichta	72.80	4.00e-147	514.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.74	0.00e+00	881.00
IUUC-Tbe-127976	Tupaia belangeri	70.97	0.00e+00	682.00
IUUC-Ttr-128472	Tursiops truncatus	90.52	0.00e+00	929.00
IUUC-Xtr-132621	Xenopus tropicalis	92.54	0.00e+00	920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence