iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-087945

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03044901

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007238.2	ENSOGAT00000007239.2	ENSOGAP00000006474.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-24	84.5	367	398
UBD/Beta-Prp	2.60e-44	151.6	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 488
           ************9888899***********986 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MPTESASCST SRQAKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACAG AAAGCGCAAG TTGTTCGACC TCTCGCCAAG CAAAACAAAA GCGCAAGTCA 60
CACAGCCTTT CCATCCGGAG AACCAACAGC TCGGAGCAGG AGCGGACAGG GCTGCCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	95.16	0.00e+00	961.00
IUUC-Apl-003647	Anas platyrhynchos	92.94	0.00e+00	936.00
IUUC-Aca-004759	Anolis carolinensis	92.54	0.00e+00	946.00
IUUC-Ame-011103	Astyanax mexicanus	55.60	6.00e-144	503.00
IUUC-Bta-012718	Bos taurus	95.36	0.00e+00	956.00
IUUC-Cel-018499	Caenorhabditis elegans	42.08	8.00e-96	343.00
IUUC-Cja-019492	Callithrix jacchus	97.18	0.00e+00	999.00
IUUC-Cfa-020199	Canis familiaris	94.76	0.00e+00	987.00
IUUC-Cpo-022500	Cavia porcellus	90.32	0.00e+00	941.00
IUUC-Csa-023567	Chlorocebus sabaeus	97.78	0.00e+00	1006.00
IUUC-Cho-025071	Choloepus hoffmanni	68.15	0.00e+00	645.00
IUUC-Cin-025460	Ciona intestinalis	45.30	1.00e-104	373.00
IUUC-Csv-026042	Ciona savignyi	46.43	9.00e-109	386.00
IUUC-Dre-028214	Danio rerio	82.06	0.00e+00	861.00
IUUC-Dno-029826	Dasypus novemcinctus	94.94	0.00e+00	826.00
IUUC-Dor-030967	Dipodomys ordii	96.25	0.00e+00	895.00
IUUC-Dme-031936	Drosophila melanogaster	49.58	6.00e-119	421.00
IUUC-Ete-032452	Echinops telfairi	92.14	0.00e+00	947.00
IUUC-Eca-033278	Equus caballus	95.56	0.00e+00	991.00
IUUC-Eeu-034592	Erinaceus europaeus	83.27	0.00e+00	830.00
IUUC-Fca-036431	Felis catus	95.77	0.00e+00	992.00
IUUC-Fal-037149	Ficedula albicollis	92.14	0.00e+00	931.00
IUUC-Gmo-038476	Gadus morhua	78.44	0.00e+00	773.00
IUUC-Gga-041099	Gallus gallus	92.94	0.00e+00	937.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.40	0.00e+00	826.00
IUUC-Ggo-044683	Gorilla gorilla	89.31	0.00e+00	908.00
IUUC-Hsa-046658	Homo sapiens	96.98	0.00e+00	998.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	97.36	0.00e+00	930.00
IUUC-Lch-050571	Latimeria chalumnae	84.06	0.00e+00	882.00
IUUC-Loc-052652	Lepisosteus oculatus	81.11	0.00e+00	860.00
IUUC-Laf-053712	Loxodonta africana	94.59	0.00e+00	978.00
IUUC-Mcc-055521	Macaca mulatta	97.78	0.00e+00	1006.00
IUUC-Meu-056324	Macropus eugenii	88.91	0.00e+00	887.00
IUUC-Mga-060114	Meleagris gallopavo	93.15	0.00e+00	944.00
IUUC-Mmr-061176	Microcebus murinus	96.98	0.00e+00	995.00
IUUC-Mdo-061888	Monodelphis domestica	93.75	0.00e+00	927.00
IUUC-Mmu-063977	Mus musculus	96.57	0.00e+00	1004.00
IUUC-Mpu-066220	Mustela putorius furo	81.55	4.00e-180	623.00
IUUC-Mlu-068155	Myotis lucifugus	95.97	0.00e+00	994.00
IUUC-Nle-069964	Nomascus leucogenys	97.18	0.00e+00	1001.00
IUUC-Opr-070925	Ochotona princeps	94.20	6.00e-151	526.00
IUUC-Ont-071317	Oreochromis niloticus	85.69	0.00e+00	846.00
IUUC-Oan-072952	Ornithorhynchus anatinus	93.55	0.00e+00	950.00
IUUC-Ocu-073913	Oryctolagus cuniculus	96.57	0.00e+00	1004.00
IUUC-Ola-087024	Oryzias latipes	84.31	0.00e+00	882.00
IUUC-Oar-089854	Ovis aries	95.77	0.00e+00	948.00
IUUC-Ptr-091486	Pan troglodytes	97.18	0.00e+00	1000.00
IUUC-Pan-091738	Papio anubis	97.78	0.00e+00	1006.00
IUUC-Psi-093953	Pelodiscus sinensis	92.14	0.00e+00	937.00
IUUC-Pma-094560	Petromyzon marinus	75.05	0.00e+00	778.00
IUUC-Pfo-097222	Poecilia formosa	83.06	0.00e+00	833.00
IUUC-Pab-098778	Pongo abelii	92.54	0.00e+00	940.00
IUUC-Pca-100852	Procavia capensis	91.94	0.00e+00	932.00
IUUC-Pva-103130	Pteropus vampyrus	95.04	1.00e-133	469.00
IUUC-Rno-105848	Rattus norvegicus	87.50	0.00e+00	887.00
IUUC-Sha-106750	Sarcophilus harrisii	93.95	0.00e+00	957.00
IUUC-Sar-113749	Sorex araneus	87.10	0.00e+00	879.00
IUUC-Ssc-115691	Sus scrofa	93.75	0.00e+00	932.00
IUUC-Tgu-117365	Taeniopygia guttata	91.53	0.00e+00	886.00
IUUC-Tru-117595	Takifugu rubripes	84.07	0.00e+00	836.00
IUUC-Tsy-118973	Tarsius syrichta	75.55	2.00e-153	535.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.13	0.00e+00	865.00
IUUC-Tbe-127976	Tupaia belangeri	71.37	0.00e+00	691.00
IUUC-Ttr-128472	Tursiops truncatus	93.35	0.00e+00	947.00
IUUC-Xtr-132621	Xenopus tropicalis	90.93	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence