iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091486

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03076995

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000002240.4	ENSPTRT00000004101.2	ENSPTRP00000003785.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-24	84.6	365	396
UBD/Beta-Prp	5.10e-45	153.9	278	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 365  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 396
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 278  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 366
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 367  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 453
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 454  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 486
           ************9888899***********986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTCGCGTC AGTGCGGAGA TAGCGGTGTC CTGCGCGTCT TCGGGTCAGT ACTGGGGGCC 60
GCGTCGTAGG GACTCACTGG CGGTGCGCGA CCCGGGCTGG CTCCGGGGGT GGCGGGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

ptr:465999

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	95.56	0.00e+00	953.00
IUUC-Apl-003647	Anas platyrhynchos	94.34	0.00e+00	938.00
IUUC-Aca-004759	Anolis carolinensis	93.33	0.00e+00	945.00
IUUC-Ame-011103	Astyanax mexicanus	56.21	2.00e-143	502.00
IUUC-Bta-012718	Bos taurus	95.16	0.00e+00	947.00
IUUC-Cel-018499	Caenorhabditis elegans	43.14	7.00e-96	343.00
IUUC-Cja-019492	Callithrix jacchus	98.59	0.00e+00	1007.00
IUUC-Cfa-020199	Canis familiaris	95.16	0.00e+00	983.00
IUUC-Cpo-022500	Cavia porcellus	90.73	0.00e+00	935.00
IUUC-Csa-023567	Chlorocebus sabaeus	99.39	0.00e+00	1013.00
IUUC-Cho-025071	Choloepus hoffmanni	68.83	0.00e+00	649.00
IUUC-Cin-025460	Ciona intestinalis	45.14	7.00e-104	370.00
IUUC-Csv-026042	Ciona savignyi	46.41	3.00e-108	385.00
IUUC-Dre-028214	Danio rerio	84.21	0.00e+00	863.00
IUUC-Dno-029826	Dasypus novemcinctus	95.90	0.00e+00	820.00
IUUC-Dor-030967	Dipodomys ordii	97.56	0.00e+00	903.00
IUUC-Dme-031936	Drosophila melanogaster	49.47	1.00e-118	420.00
IUUC-Ete-032452	Echinops telfairi	93.72	0.00e+00	956.00
IUUC-Eca-033278	Equus caballus	95.97	0.00e+00	986.00
IUUC-Eeu-034592	Erinaceus europaeus	84.21	0.00e+00	837.00
IUUC-Fca-036431	Felis catus	96.18	0.00e+00	988.00
IUUC-Fal-037149	Ficedula albicollis	93.13	0.00e+00	932.00
IUUC-Gmo-038476	Gadus morhua	79.36	0.00e+00	777.00
IUUC-Gga-041099	Gallus gallus	93.94	0.00e+00	937.00
IUUC-Gac-042374	Gasterosteus aculeatus	83.20	0.00e+00	818.00
IUUC-Ggo-044683	Gorilla gorilla	92.11	0.00e+00	929.00
IUUC-Hsa-046658	Homo sapiens	99.80	0.00e+00	1019.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	97.80	0.00e+00	925.00
IUUC-Lch-050571	Latimeria chalumnae	84.22	0.00e+00	879.00
IUUC-Loc-052652	Lepisosteus oculatus	81.99	0.00e+00	865.00
IUUC-Laf-053712	Loxodonta africana	94.79	0.00e+00	971.00
IUUC-Mcc-055521	Macaca mulatta	99.39	0.00e+00	1013.00
IUUC-Meu-056324	Macropus eugenii	90.28	0.00e+00	894.00
IUUC-Mga-060114	Meleagris gallopavo	93.75	0.00e+00	937.00
IUUC-Mmr-061176	Microcebus murinus	97.17	0.00e+00	994.00
IUUC-Mdo-061888	Monodelphis domestica	94.35	0.00e+00	923.00
IUUC-Mmu-063977	Mus musculus	96.77	0.00e+00	997.00
IUUC-Mpu-066220	Mustela putorius furo	82.62	1.00e-179	622.00
IUUC-Mlu-068155	Myotis lucifugus	96.17	0.00e+00	990.00
IUUC-Nle-069964	Nomascus leucogenys	99.60	0.00e+00	1014.00
IUUC-Opr-070925	Ochotona princeps	96.35	3.00e-153	535.00
IUUC-Ont-071317	Oreochromis niloticus	85.69	0.00e+00	837.00
IUUC-Oan-072952	Ornithorhynchus anatinus	94.56	0.00e+00	945.00
IUUC-Ocu-073913	Oryctolagus cuniculus	96.98	0.00e+00	999.00
IUUC-Ola-087024	Oryzias latipes	84.51	0.00e+00	879.00
IUUC-Oga-087945	Otolemur garnettii	97.18	0.00e+00	1000.00
IUUC-Oar-089854	Ovis aries	95.56	0.00e+00	941.00
IUUC-Pan-091738	Papio anubis	99.39	0.00e+00	1013.00
IUUC-Psi-093953	Pelodiscus sinensis	93.15	0.00e+00	931.00
IUUC-Pma-094560	Petromyzon marinus	74.26	0.00e+00	773.00
IUUC-Pfo-097222	Poecilia formosa	84.82	0.00e+00	835.00
IUUC-Pab-098778	Pongo abelii	94.74	0.00e+00	952.00
IUUC-Pca-100852	Procavia capensis	92.91	0.00e+00	939.00
IUUC-Pva-103130	Pteropus vampyrus	94.63	1.00e-133	469.00
IUUC-Rno-105848	Rattus norvegicus	87.70	0.00e+00	880.00
IUUC-Sha-106750	Sarcophilus harrisii	94.56	0.00e+00	951.00
IUUC-Sar-113749	Sorex araneus	88.06	0.00e+00	887.00
IUUC-Ssc-115691	Sus scrofa	93.74	0.00e+00	931.00
IUUC-Tgu-117365	Taeniopygia guttata	92.53	0.00e+00	886.00
IUUC-Tru-117595	Takifugu rubripes	83.27	0.00e+00	830.00
IUUC-Tsy-118973	Tarsius syrichta	77.62	7.00e-157	546.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.33	0.00e+00	863.00
IUUC-Tbe-127976	Tupaia belangeri	71.86	0.00e+00	696.00
IUUC-Ttr-128472	Tursiops truncatus	93.72	0.00e+00	952.00
IUUC-Xtr-132621	Xenopus tropicalis	91.52	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence