iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013485

Ensembl Protein ID

ENSBTAP00000006351.5

UniProt Accession

F1MJ53; F1MJ53_BOVIN

Genbank Protein ID

ENSBTAP00000006351

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02013173

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004832.5	ENSBTAT00000006351.5	ENSBTAP00000006351.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-29	100.4	1345	1379
UBD/Beta-Prp	7.60e-45	153.5	1449	1662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1345 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1379
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e+++++++++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +ir++d+ +g       
   Q: 1449 SGENQINQISLNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDRisNGqDLIITGSKDHYIRMFDVTEGALGTVtp 1534
           56789*********9.99*************************************99888*****************9998765567 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++h+  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l++ +  + l+sg + g +klw++ t   v
   Q: 1535 thnFEPPHYDGIEALTIHG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALEVVPGHPVLLSGCRGGILKLWNIDTFVPV 1619
           788999*************..6799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1620 GEMKGHESPINAICVN--STHIFTAADDRTVRIWktrNLQDGQIS 1662
           ***********99888..****************88888888775 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

FIVSYFISSC FLPHRIRPQL AKERIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ 60
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIIEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTATTGTAT CTTATTTTAT TTCTTCCTGT TTTTTACCTC ACAGAATAAG ACCACAGCTT 60
GCCAAAGAAA GGATTGAAGG ATGCCATATT TGTACATCTG TAACACCTGG AGAACCTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	95.86	0.00e+00	3041.00
IUUC-Apl-003353	Anas platyrhynchos	84.19	0.00e+00	2651.00
IUUC-Aca-004467	Anolis carolinensis	83.96	0.00e+00	2713.00
IUUC-Ame-011430	Astyanax mexicanus	65.38	0.00e+00	1295.00
IUUC-Cel-018402	Caenorhabditis elegans	53.27	2.00e-145	510.00
IUUC-Cja-019385	Callithrix jacchus	92.58	0.00e+00	2926.00
IUUC-Cfa-020986	Canis familiaris	96.06	0.00e+00	3005.00
IUUC-Cpo-022297	Cavia porcellus	91.69	0.00e+00	2865.00
IUUC-Csa-023685	Chlorocebus sabaeus	94.49	0.00e+00	2977.00
IUUC-Cho-024531	Choloepus hoffmanni	92.30	0.00e+00	1091.00
IUUC-Cin-025160	Ciona intestinalis	46.73	9.00e-88	317.00
IUUC-Csv-026158	Ciona savignyi	57.43	2.00e-177	617.00
IUUC-Dre-028532	Danio rerio	67.08	0.00e+00	2095.00
IUUC-Dno-029972	Dasypus novemcinctus	90.82	0.00e+00	2776.00
IUUC-Ete-032872	Echinops telfairi	79.48	0.00e+00	1030.00
IUUC-Eca-033518	Equus caballus	96.15	0.00e+00	3025.00
IUUC-Fca-036197	Felis catus	95.86	0.00e+00	2994.00
IUUC-Fal-037534	Ficedula albicollis	83.43	0.00e+00	2640.00
IUUC-Gmo-039407	Gadus morhua	65.80	0.00e+00	1928.00
IUUC-Gga-040687	Gallus gallus	83.78	0.00e+00	2610.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.43	0.00e+00	2170.00
IUUC-Ggo-044457	Gorilla gorilla	95.26	0.00e+00	2984.00
IUUC-Hsa-046372	Homo sapiens	95.44	0.00e+00	2994.00
IUUC-Lch-049786	Latimeria chalumnae	59.69	0.00e+00	1873.00
IUUC-Loc-052689	Lepisosteus oculatus	74.33	0.00e+00	2372.00
IUUC-Laf-054018	Loxodonta africana	89.73	0.00e+00	2767.00
IUUC-Mcc-055558	Macaca mulatta	95.32	0.00e+00	2996.00
IUUC-Meu-056080	Macropus eugenii	86.86	0.00e+00	973.00
IUUC-Mga-059283	Meleagris gallopavo	83.24	0.00e+00	2582.00
IUUC-Mmr-060773	Microcebus murinus	93.59	0.00e+00	2892.00
IUUC-Mdo-062688	Monodelphis domestica	89.38	0.00e+00	2618.00
IUUC-Mmu-063997	Mus musculus	91.26	0.00e+00	2834.00
IUUC-Mpu-066354	Mustela putorius furo	94.54	0.00e+00	2983.00
IUUC-Mlu-067599	Myotis lucifugus	94.81	0.00e+00	2952.00
IUUC-Nle-069477	Nomascus leucogenys	95.44	0.00e+00	2993.00
IUUC-Opr-070188	Ochotona princeps	79.62	0.00e+00	1769.00
IUUC-Ont-071938	Oreochromis niloticus	69.04	0.00e+00	2180.00
IUUC-Oan-073055	Ornithorhynchus anatinus	87.67	0.00e+00	2642.00
IUUC-Ocu-074302	Oryctolagus cuniculus	92.29	0.00e+00	2921.00
IUUC-Ola-086604	Oryzias latipes	66.15	0.00e+00	2086.00
IUUC-Oga-088799	Otolemur garnettii	93.51	0.00e+00	2672.00
IUUC-Oar-089629	Ovis aries	96.46	0.00e+00	3041.00
IUUC-Pan-092214	Papio anubis	94.06	0.00e+00	2967.00
IUUC-Psi-093757	Pelodiscus sinensis	81.07	0.00e+00	2532.00
IUUC-Pfo-096978	Poecilia formosa	62.97	0.00e+00	1258.00
IUUC-Pab-097984	Pongo abelii	95.50	0.00e+00	2968.00
IUUC-Pca-101061	Procavia capensis	77.21	0.00e+00	1742.00
IUUC-Pva-102306	Pteropus vampyrus	93.23	0.00e+00	2875.00
IUUC-Rno-105354	Rattus norvegicus	90.08	0.00e+00	2793.00
IUUC-Sha-106938	Sarcophilus harrisii	88.72	0.00e+00	1811.00
IUUC-Ssc-115810	Sus scrofa	95.75	0.00e+00	2960.00
IUUC-Tgu-117076	Taeniopygia guttata	81.58	0.00e+00	2511.00
IUUC-Tru-118091	Takifugu rubripes	63.97	0.00e+00	1252.00
IUUC-Tsy-119020	Tarsius syrichta	93.61	0.00e+00	2956.00
IUUC-Tni-120813	Tetraodon nigroviridis	65.97	0.00e+00	2094.00
IUUC-Tbe-127494	Tupaia belangeri	81.48	0.00e+00	1027.00
IUUC-Ttr-128393	Tursiops truncatus	89.33	0.00e+00	2759.00
IUUC-Vpa-130675	Vicugna pacos	81.08	0.00e+00	774.00
IUUC-Xtr-132829	Xenopus tropicalis	78.73	0.00e+00	2518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence