iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090045

Ensembl Protein ID

ENSOARP00000012800.1

UniProt Accession

W5PQS3; W5PQS3_SHEEP

Genbank Protein ID

ENSOARP00000012800

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01083793

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000011934.1	ENSOART00000012987.1	ENSOARP00000012800.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.20e-19	67.7	296	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 296  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 343
           8*********88.6*******************.*******7.******75 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

VPLTPLAGVY AAEFVPPPEC PVFEPSWEEF TDPLSFIGRI RPMAEKTGIC KIRPPKDWQP 60
PFACEVKSFR FTPRVQRLNE LEAMTRVRLD FLDQLAKFWE LQGSTLKIPV VERKILDLYA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCCCTTA CCCCCCTGGC GGGCGTCTAC GCGGCGGAGT TCGTGCCGCC CCCAGAGTGC 60
CCGGTGTTTG AGCCCAGCTG GGAGGAGTTC ACAGATCCCC TCAGCTTCAT CGGCCGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	97.93	0.00e+00	2931.00
IUUC-Atr-002595	Amborella trichopoda	31.05	3.00e-122	434.00
IUUC-Apl-004141	Anas platyrhynchos	91.10	0.00e+00	2764.00
IUUC-Aca-004952	Anolis carolinensis	89.66	0.00e+00	2790.00
IUUC-Aly-006097	Arabidopsis lyrata	63.64	4.00e-09	58.50
IUUC-Acl-008162	Aspergillus clavatus	30.97	2.00e-120	427.00
IUUC-Ate-010453	Aspergillus terreus	29.23	3.00e-115	410.00
IUUC-Ame-011323	Astyanax mexicanus	76.16	0.00e+00	2026.00
IUUC-Bgr-012241	Blumeria graminis	29.92	3.00e-112	400.00
IUUC-Bta-012902	Bos taurus	99.47	0.00e+00	3046.00
IUUC-Bdi-014050	Brachypodium distachyon	30.23	7.00e-119	422.00
IUUC-Cja-018988	Callithrix jacchus	95.57	0.00e+00	2762.00
IUUC-Cfa-020212	Canis familiaris	96.80	0.00e+00	2890.00
IUUC-Cpo-022221	Cavia porcellus	96.43	0.00e+00	2061.00
IUUC-Csa-023575	Chlorocebus sabaeus	97.65	0.00e+00	2844.00
IUUC-Cho-024280	Choloepus hoffmanni	91.63	0.00e+00	2689.00
IUUC-Cin-025321	Ciona intestinalis	48.47	0.00e+00	1059.00
IUUC-Csv-026185	Ciona savignyi	47.80	0.00e+00	1151.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	28.09	3.00e-109	390.00
IUUC-Dre-027909	Danio rerio	75.68	0.00e+00	1635.00
IUUC-Dno-029473	Dasypus novemcinctus	97.09	0.00e+00	2697.00
IUUC-Dor-030281	Dipodomys ordii	95.09	0.00e+00	1219.00
IUUC-Dme-032021	Drosophila melanogaster	47.27	0.00e+00	1107.00
IUUC-Eca-034265	Equus caballus	97.14	0.00e+00	2952.00
IUUC-Fca-035476	Felis catus	96.80	0.00e+00	2925.00
IUUC-Fal-037078	Ficedula albicollis	91.37	0.00e+00	2476.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.09	4.00e-107	383.00
IUUC-Gga-040466	Gallus gallus	90.01	0.00e+00	2838.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.24	0.00e+00	2093.00
IUUC-Ggo-044524	Gorilla gorilla	90.72	0.00e+00	2498.00
IUUC-Hsa-045821	Homo sapiens	97.27	0.00e+00	2952.00
IUUC-Kpa-049245	Komagataella pastoris	22.86	4.00e-40	160.00
IUUC-Lch-050630	Latimeria chalumnae	73.99	0.00e+00	2083.00
IUUC-Loc-051963	Lepisosteus oculatus	75.73	0.00e+00	2041.00
IUUC-Laf-053918	Loxodonta africana	90.33	0.00e+00	2550.00
IUUC-Mcc-055672	Macaca mulatta	96.20	0.00e+00	2944.00
IUUC-Mor-057198	Magnaporthe oryzae	30.81	2.00e-118	421.00
IUUC-Mpo-057317	Magnaporthe poae	30.31	3.00e-108	387.00
IUUC-Mga-059192	Meleagris gallopavo	82.02	0.00e+00	2393.00
IUUC-Mmr-060968	Microcebus murinus	95.44	0.00e+00	2940.00
IUUC-Mdo-062945	Monodelphis domestica	94.69	0.00e+00	2761.00
IUUC-Mmu-063614	Mus musculus	95.26	0.00e+00	2909.00
IUUC-Mpu-066349	Mustela putorius furo	97.86	0.00e+00	2843.00
IUUC-Mlu-067363	Myotis lucifugus	97.51	0.00e+00	2994.00
IUUC-Nle-070142	Nomascus leucogenys	97.27	0.00e+00	2962.00
IUUC-Opr-071002	Ochotona princeps	89.99	0.00e+00	1380.00
IUUC-Ont-072471	Oreochromis niloticus	77.57	0.00e+00	1853.00
IUUC-Oan-072797	Ornithorhynchus anatinus	78.69	0.00e+00	2008.00
IUUC-Ocu-074164	Oryctolagus cuniculus	95.97	0.00e+00	2989.00
IUUC-Oba-075388	Oryza barthii	27.11	3.00e-81	297.00
IUUC-Obr-076296	Oryza brachyantha	30.86	2.00e-95	345.00
IUUC-Ogu-079040	Oryza glumaepatula	27.35	1.00e-81	299.00
IUUC-Ome-081764	Oryza meridionalis	29.23	1.00e-99	358.00
IUUC-Oni-083012	Oryza nivara	27.26	4.00e-81	297.00
IUUC-Oru-084630	Oryza rufipogon	26.95	2.00e-80	295.00
IUUC-Ola-087076	Oryzias latipes	74.80	0.00e+00	2081.00
IUUC-Oga-088350	Otolemur garnettii	94.72	0.00e+00	2854.00
IUUC-Ptr-091199	Pan troglodytes	96.86	0.00e+00	2940.00
IUUC-Pan-092094	Papio anubis	92.88	0.00e+00	2866.00
IUUC-Psi-093550	Pelodiscus sinensis	90.31	0.00e+00	2731.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.50	1.00e-116	415.00
IUUC-Pfo-097266	Poecilia formosa	77.61	0.00e+00	1829.00
IUUC-Pab-098576	Pongo abelii	97.51	0.00e+00	2948.00
IUUC-Pca-100123	Procavia capensis	92.94	0.00e+00	1630.00
IUUC-Pva-103109	Pteropus vampyrus	91.71	0.00e+00	2773.00
IUUC-Pte-104195	Pyrenophora teres	29.74	4.00e-122	433.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.37	4.00e-124	440.00
IUUC-Rno-105664	Rattus norvegicus	95.26	0.00e+00	2904.00
IUUC-Sha-107506	Sarcophilus harrisii	92.75	0.00e+00	2521.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.68	9.00e-52	199.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	62.40
IUUC-Sit-110534	Setaria italica	29.47	1.00e-119	425.00
IUUC-Sar-113052	Sorex araneus	96.00	0.00e+00	2919.00
IUUC-Tgu-116613	Taeniopygia guttata	90.07	0.00e+00	2784.00
IUUC-Tru-118604	Takifugu rubripes	74.75	0.00e+00	2130.00
IUUC-Tsy-119237	Tarsius syrichta	97.19	0.00e+00	1295.00
IUUC-Tni-120779	Tetraodon nigroviridis	74.33	0.00e+00	2108.00
IUUC-Tre-122213	Trichoderma reesei	29.29	4.00e-111	396.00
IUUC-Tvi-122263	Trichoderma virens	29.03	2.00e-109	391.00
IUUC-Tae-125894	Triticum aestivum	29.88	5.00e-112	400.00
IUUC-Tme-127087	Tuber melanosporum	31.09	3.00e-131	463.00
IUUC-Tbe-127627	Tupaia belangeri	98.24	0.00e+00	800.00
IUUC-Ttr-129242	Tursiops truncatus	96.32	0.00e+00	2884.00
IUUC-Vda-129733	Verticillium dahliae	28.75	8.00e-102	365.00
IUUC-Vpa-130429	Vicugna pacos	90.34	0.00e+00	1460.00
IUUC-Xtr-131762	Xenopus tropicalis	76.19	0.00e+00	2221.00
IUUC-Xma-133693	Xiphophorus maculatus	74.53	0.00e+00	2096.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence