iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054635

Ensembl Protein ID

ENSMMUP00000048949.1

UniProt Accession

A0A1D5QLM4; A0A1D5QLM4_MACMU

Genbank Protein ID

ENSMMUP00000048949

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03004566

Gene Name

EFCAB8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000037750.1	ENSMMUT00000061392.1	ENSMMUP00000048949.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-16	60.3	372	398
UBD/Beta-Prp	1.40e-40	140.4	368	601

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWD 29
           ++ c+++ ++ ++lv+G++D  i++W+
   Q: 372  GILCFDYcPErNFLVTGGYDAFIRLWN 398
           4889999*999***************9 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..... 131
              +++ + ++ p++++lvtg+ D++i++w ++ +  +v  +kgh+ sv+ + ++  +++ l+s s+d+ irvwd+  + cl++     
   Q: 368  HVRKGILCFDYCPERNFLVTGGYDAFIRLWnPFVSKRPVWLMKGHQTSVTHILVDSrNSSILISVSKDKNIRVWDMLDYICLQSfcgkf 456
           34445666666666666666666666666633335555555666666666666655444666666666666666666666666666666 PP
   S: 132  ..........................................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl.. 175
                                                      ++ ++ +  c+v+ ++  + +vsG+l ++v +W + tg+   ++  
   Q: 457  falgncpitsayffekdntlicstysigilkgyleaqgpikaRKRTTHCSPLCAVLYSKIfKQVVSGCLRGIVSVWEVVTGRKTMEFsv 545
           6666666666666666666666666666666666666665556666666777888888888*******************999999999 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs 231
           +gg++   + +++d++ ++l++g +dgt k+w++  g+c+ t+ + ++   s   +
   Q: 546  SGGQHVELTAMALDESERCLLTGLRDGTMKMWNYNIGKCLLTFPNPDQLEISGIIH 601
           999****************************************9987665555555 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSSEDLAEIP QLQKLSVPHG FQNKEAVSSP TPSITLSQVP DLQPGSQLFT EVHLAKIEKM 60
FEEDINSTGA LGMDAFIKAM KKVLSCVSNE MLKELFLKVD SDCEGFVTWQ KYVDYMMREF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCACCTGC CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAACCAC CGCGCCCAGC 60
CTGAATCATG TTTTTTTGAA ACCATTGGCA TCTGAACCTG TAATTCTGTC GGGTAGTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

KEGG

mcc:714971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	25.98	1.00e-62	234.00
IUUC-Aca-005140	Anolis carolinensis	28.05	5.00e-63	236.00
IUUC-Ame-011677	Astyanax mexicanus	30.31	8.00e-35	141.00
IUUC-Bta-013449	Bos taurus	32.18	7.00e-35	142.00
IUUC-Cja-020006	Callithrix jacchus	87.85	0.00e+00	1372.00
IUUC-Cfa-020765	Canis familiaris	65.61	0.00e+00	1628.00
IUUC-Cho-024437	Choloepus hoffmanni	30.77	8.00e-24	105.00
IUUC-Cin-025265	Ciona intestinalis	26.85	3.00e-71	263.00
IUUC-Csv-026326	Ciona savignyi	27.30	4.00e-31	129.00
IUUC-Dre-027573	Danio rerio	26.89	4.00e-60	226.00
IUUC-Dno-029238	Dasypus novemcinctus	62.61	0.00e+00	1566.00
IUUC-Dor-030182	Dipodomys ordii	31.48	8.00e-36	145.00
IUUC-Dme-031984	Drosophila melanogaster	22.28	3.00e-48	187.00
IUUC-Ete-033152	Echinops telfairi	32.20	8.00e-34	138.00
IUUC-Eeu-034535	Erinaceus europaeus	25.89	1.00e-18	88.20
IUUC-Fca-036363	Felis catus	27.34	3.00e-60	226.00
IUUC-Gmo-039551	Gadus morhua	30.19	3.00e-32	133.00
IUUC-Gac-041482	Gasterosteus aculeatus	31.61	4.00e-34	139.00
IUUC-Ggo-044932	Gorilla gorilla	91.69	0.00e+00	2377.00
IUUC-Hsa-046963	Homo sapiens	91.85	0.00e+00	2371.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	31.05	1.00e-37	150.00
IUUC-Lch-050281	Latimeria chalumnae	40.34	1.00e-156	547.00
IUUC-Loc-052029	Lepisosteus oculatus	42.42	2.00e-157	549.00
IUUC-Laf-054508	Loxodonta africana	76.02	0.00e+00	706.00
IUUC-Mmr-061370	Microcebus murinus	67.85	0.00e+00	1622.00
IUUC-Mdo-061862	Monodelphis domestica	48.78	0.00e+00	1085.00
IUUC-Mmu-063271	Mus musculus	76.74	4.00e-168	583.00
IUUC-Mpu-066224	Mustela putorius furo	64.82	0.00e+00	1588.00
IUUC-Mlu-068140	Myotis lucifugus	31.23	6.00e-36	145.00
IUUC-Ont-072106	Oreochromis niloticus	25.47	3.00e-48	187.00
IUUC-Oan-072752	Ornithorhynchus anatinus	31.21	7.00e-37	148.00
IUUC-Ocu-074664	Oryctolagus cuniculus	72.85	0.00e+00	1436.00
IUUC-Ola-086882	Oryzias latipes	29.33	6.00e-35	141.00
IUUC-Oga-087999	Otolemur garnettii	28.21	1.00e-60	228.00
IUUC-Oar-089288	Ovis aries	67.25	0.00e+00	1649.00
IUUC-Psi-093985	Pelodiscus sinensis	43.13	7.00e-134	471.00
IUUC-Pma-094599	Petromyzon marinus	33.45	6.00e-42	165.00
IUUC-Pfo-097353	Poecilia formosa	25.83	8.00e-54	204.00
IUUC-Pab-098444	Pongo abelii	32.10	3.00e-34	139.00
IUUC-Pva-102863	Pteropus vampyrus	30.46	2.00e-33	137.00
IUUC-Rno-105331	Rattus norvegicus	30.28	3.00e-40	160.00
IUUC-Sha-106832	Sarcophilus harrisii	29.07	5.00e-39	155.00
IUUC-Smo-109247	Selaginella moellendorffii	24.55	2.00e-41	164.00
IUUC-Ssc-115233	Sus scrofa	79.72	9.00e-81	292.00
IUUC-Tru-117566	Takifugu rubripes	31.70	1.00e-30	127.00
IUUC-Tni-120449	Tetraodon nigroviridis	31.77	3.00e-30	126.00
IUUC-Tbe-127509	Tupaia belangeri	31.06	3.00e-34	140.00
IUUC-Ttr-128571	Tursiops truncatus	29.52	3.00e-32	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence