iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048623

Ensembl Protein ID

ENSSTOP00000004669.2

UniProt Accession

I3M5N1; I3M5N1_ICTTR

Genbank Protein ID

ENSSTOP00000004669

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01061935

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005210.2	ENSSTOT00000005202.2	ENSSTOP00000004669.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-39	131.0	206	240
UBD/Beta-Prp	4.00e-52	177.2	29	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 206  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 240
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++     
   Q: 29   TRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRv 117
           56899*****************************************************************************9877766 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c +++
   Q: 118  srELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSF 204
           779*************99.67789***********************9.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           +gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ 
   Q: 205  TGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 249
           *************************************99888874 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

QDARKACNDA TLVQITSNMD SVGRIQMRTR RTLRGHLAKI YAMHWGYDSR LLVSASQDGK 60
LIIWDSYTTN KMHAIPLRSS WVMTCAYAPS GNYVACGGLD NICSIYNLKT REGNVRVSRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGATGCCA GGAAAGCATG TAATGATGCA ACGCTTGTTC AGGTAAAGTT TTTTCCCCCC 60
CAATTTGTTT TAGTGATTCA TATGAAGTAA CTTGACACTG ATACAGATGA CTTGGAGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	99.69	0.00e+00	661.00
IUUC-Apl-003923	Anas platyrhynchos	94.74	2.00e-174	604.00
IUUC-Aca-004754	Anolis carolinensis	94.72	3.00e-175	606.00
IUUC-Ate-010520	Aspergillus terreus	61.76	8.00e-110	389.00
IUUC-Bta-013200	Bos taurus	99.69	0.00e+00	661.00
IUUC-Cja-019845	Callithrix jacchus	99.69	0.00e+00	660.00
IUUC-Cfa-020395	Canis familiaris	99.69	0.00e+00	661.00
IUUC-Cpo-021376	Cavia porcellus	99.07	0.00e+00	660.00
IUUC-Csa-023295	Chlorocebus sabaeus	100.00	0.00e+00	662.00
IUUC-Cho-024766	Choloepus hoffmanni	99.69	0.00e+00	662.00
IUUC-Dno-029802	Dasypus novemcinctus	99.34	1.00e-180	624.00
IUUC-Ete-032710	Echinops telfairi	96.75	3.00e-179	620.00
IUUC-Eca-033628	Equus caballus	99.38	0.00e+00	660.00
IUUC-Eeu-034978	Erinaceus europaeus	97.44	5.00e-157	546.00
IUUC-Fal-037616	Ficedula albicollis	95.03	9.00e-176	608.00
IUUC-Gmo-039556	Gadus morhua	92.55	1.00e-179	621.00
IUUC-Gga-040249	Gallus gallus	95.03	9.00e-176	608.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.61	2.00e-179	621.00
IUUC-Ggo-044954	Gorilla gorilla	99.69	0.00e+00	661.00
IUUC-Hsa-046105	Homo sapiens	100.00	0.00e+00	662.00
IUUC-Mcc-055787	Macaca mulatta	100.00	0.00e+00	662.00
IUUC-Mga-060050	Meleagris gallopavo	94.74	2.00e-174	604.00
IUUC-Mmr-060931	Microcebus murinus	100.00	0.00e+00	662.00
IUUC-Mdo-063055	Monodelphis domestica	94.41	4.00e-175	606.00
IUUC-Mmu-064368	Mus musculus	96.58	0.00e+00	646.00
IUUC-Mpu-066358	Mustela putorius furo	99.69	0.00e+00	661.00
IUUC-Mlu-067328	Myotis lucifugus	98.76	0.00e+00	655.00
IUUC-Nle-069612	Nomascus leucogenys	100.00	0.00e+00	662.00
IUUC-Ont-071287	Oreochromis niloticus	92.55	2.00e-179	620.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.34	9.00e-177	612.00
IUUC-Ocu-074126	Oryctolagus cuniculus	99.38	0.00e+00	665.00
IUUC-Ola-087297	Oryzias latipes	92.24	7.00e-179	619.00
IUUC-Oar-089360	Ovis aries	99.69	0.00e+00	661.00
IUUC-Ptr-091437	Pan troglodytes	100.00	0.00e+00	662.00
IUUC-Pan-092195	Papio anubis	99.69	0.00e+00	660.00
IUUC-Psi-093718	Pelodiscus sinensis	95.03	9.00e-176	608.00
IUUC-Pfo-096251	Poecilia formosa	92.24	5.00e-179	619.00
IUUC-Sha-106534	Sarcophilus harrisii	94.41	2.00e-175	607.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	7.00e-60	223.00
IUUC-Spo-108352	Schizosaccharomyces pombe	41.69	1.00e-69	255.00
IUUC-Sar-113642	Sorex araneus	99.26	2.00e-160	558.00
IUUC-Tgu-117198	Taeniopygia guttata	95.03	9.00e-176	608.00
IUUC-Tru-118399	Takifugu rubripes	91.93	3.00e-179	620.00
IUUC-Tsy-119354	Tarsius syrichta	96.58	0.00e+00	643.00
IUUC-Ttr-129243	Tursiops truncatus	100.00	0.00e+00	662.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence