iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060063

Ensembl Protein ID

ENSMGAP00000004779.2

UniProt Accession

G1N076; G1N076_MELGA

Protein Name

Uncharacterized protein

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004860.2	ENSMGAT00000005501.2	ENSMGAP00000004779.2
ENSMGAG00000004860.2	ENSMGAT00000005486.2	ENSMGAP00000004764.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-29	100.7	118	156
UBD/Beta-Prp	2.80e-53	180.8	220	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll 
   Q: 118  GHLSSVYCIAFdrSGRRIFTGSDDCLVKIWATDDGRLLS 156
           8**********96669******************99875 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v+++
   Q: 220  TRYLTSTGADGTICFWQWHANTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKMAELESHTDKVVAV 308
           689***************997776677764444444444449************************88888****************** PP
   S: 101  sfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           +f+ +g   ++vsGs+d t+rvw+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W+++tg+l
   Q: 309  QFCNNGdsLRFVSGSRDGTARVWQYHQQEWKSVvldmatkmtgnnvasgEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQL 397
           ****8832468**************9999998899**********8888888888899******************************* PP
   S: 172  lrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           l+ l+g h+d v  l+   fd+  + ++s+++dg + +wd+ +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 398  LHSLSG-HDDEVFVLEahpFDQ--RIVLSAGHDGNIFIWDIDKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 479
           *****9.*********554544..8999******************988877554555577777899999999999998887765 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VAVNAHIPPD YLLRICERLG PLLDKEIPQS VLGVQTLLGV GRQSLLRAAK DFRHTLWKGS 60
AFAALHRGRP PELPVNYGKP PNVVNILSAR QLTGCGRFSH LFPTSTYQQM KMHKRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCTGTCA ATGCACACAT CCCTCCAGAT TATCTTCTTA GGATCTGTGA GAGACTCGGA 60
CCGCTTTTAG ACAAGGAAAT CCCACAGAGC GTCTTGGGTG TGCAGACCTT GCTGGGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	82.48	0.00e+00	2487.00
IUUC-Atr-002600	Amborella trichopoda	31.83	1.00e-61	232.00
IUUC-Apl-004016	Anas platyrhynchos	91.60	0.00e+00	2531.00
IUUC-Aca-004722	Anolis carolinensis	83.51	0.00e+00	2367.00
IUUC-Ame-010602	Astyanax mexicanus	75.82	0.00e+00	1144.00
IUUC-Bta-013198	Bos taurus	81.19	0.00e+00	2345.00
IUUC-Cfa-020963	Canis familiaris	82.36	0.00e+00	2479.00
IUUC-Cpo-022448	Cavia porcellus	76.99	0.00e+00	2339.00
IUUC-Csa-023166	Chlorocebus sabaeus	83.04	0.00e+00	2443.00
IUUC-Cin-025553	Ciona intestinalis	40.07	2.00e-114	406.00
IUUC-Dre-028508	Danio rerio	67.88	0.00e+00	1836.00
IUUC-Dno-030070	Dasypus novemcinctus	80.92	0.00e+00	2351.00
IUUC-Dor-031052	Dipodomys ordii	74.83	0.00e+00	1090.00
IUUC-Ete-032650	Echinops telfairi	81.61	0.00e+00	1609.00
IUUC-Eca-033953	Equus caballus	83.82	0.00e+00	2306.00
IUUC-Eeu-034871	Erinaceus europaeus	74.80	0.00e+00	1138.00
IUUC-Fca-036099	Felis catus	82.06	0.00e+00	2464.00
IUUC-Fal-037246	Ficedula albicollis	94.60	0.00e+00	2734.00
IUUC-Gmo-039451	Gadus morhua	54.92	1.00e-166	579.00
IUUC-Gga-041097	Gallus gallus	97.70	0.00e+00	2855.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.72	0.00e+00	1789.00
IUUC-Hsa-045666	Homo sapiens	83.04	0.00e+00	2447.00
IUUC-Lch-050646	Latimeria chalumnae	61.41	0.00e+00	1773.00
IUUC-Loc-051802	Lepisosteus oculatus	72.06	0.00e+00	2057.00
IUUC-Laf-053942	Loxodonta africana	82.96	0.00e+00	2490.00
IUUC-Mcc-054645	Macaca mulatta	83.17	0.00e+00	2448.00
IUUC-Meu-056321	Macropus eugenii	73.18	0.00e+00	1070.00
IUUC-Mmr-061262	Microcebus murinus	83.50	0.00e+00	2478.00
IUUC-Mdo-062320	Monodelphis domestica	71.29	0.00e+00	2285.00
IUUC-Mmu-063163	Mus musculus	82.79	0.00e+00	2435.00
IUUC-Mpu-066628	Mustela putorius furo	82.33	0.00e+00	2492.00
IUUC-Mlu-068082	Myotis lucifugus	82.04	0.00e+00	2419.00
IUUC-Nle-069609	Nomascus leucogenys	83.24	0.00e+00	2457.00
IUUC-Opr-070971	Ochotona princeps	60.13	1.00e-169	591.00
IUUC-Ont-071589	Oreochromis niloticus	63.73	0.00e+00	1771.00
IUUC-Oan-072954	Ornithorhynchus anatinus	63.94	0.00e+00	1763.00
IUUC-Ocu-074122	Oryctolagus cuniculus	83.07	0.00e+00	1833.00
IUUC-Ogl-077493	Oryza glaberrima	30.62	2.00e-50	194.00
IUUC-Ogu-078641	Oryza glumaepatula	30.88	6.00e-49	189.00
IUUC-Oin-079669	Oryza indica	32.27	8.00e-52	198.00
IUUC-Olo-080755	Oryza longistaminata	32.49	1.00e-52	202.00
IUUC-Oni-082991	Oryza nivara	30.54	5.00e-49	190.00
IUUC-Ola-086580	Oryzias latipes	66.55	0.00e+00	1818.00
IUUC-Oga-089053	Otolemur garnettii	82.99	0.00e+00	2450.00
IUUC-Oar-090042	Ovis aries	81.77	0.00e+00	2473.00
IUUC-Ptr-091268	Pan troglodytes	82.97	0.00e+00	2444.00
IUUC-Pan-092376	Papio anubis	83.17	0.00e+00	2448.00
IUUC-Psi-093408	Pelodiscus sinensis	90.66	0.00e+00	2704.00
IUUC-Pfo-096515	Poecilia formosa	66.00	0.00e+00	1718.00
IUUC-Pab-097672	Pongo abelii	81.14	0.00e+00	2412.00
IUUC-Pca-101128	Procavia capensis	70.84	0.00e+00	1053.00
IUUC-Pva-102512	Pteropus vampyrus	87.50	0.00e+00	2045.00
IUUC-Rno-105797	Rattus norvegicus	82.39	0.00e+00	2421.00
IUUC-Sha-107061	Sarcophilus harrisii	74.57	0.00e+00	2399.00
IUUC-Sit-110017	Setaria italica	32.35	1.00e-54	208.00
IUUC-Sar-113004	Sorex araneus	68.60	0.00e+00	1229.00
IUUC-Ssc-116195	Sus scrofa	64.10	0.00e+00	877.00
IUUC-Tgu-117254	Taeniopygia guttata	94.66	0.00e+00	2745.00
IUUC-Tru-118186	Takifugu rubripes	66.43	0.00e+00	1758.00
IUUC-Tsy-119003	Tarsius syrichta	78.66	0.00e+00	2262.00
IUUC-Tni-120110	Tetraodon nigroviridis	66.05	0.00e+00	1746.00
IUUC-Tbe-127479	Tupaia belangeri	58.28	0.00e+00	848.00
IUUC-Ttr-129265	Tursiops truncatus	82.49	0.00e+00	2375.00
IUUC-Vpa-130736	Vicugna pacos	72.46	0.00e+00	1174.00
IUUC-Xtr-132717	Xenopus tropicalis	60.95	0.00e+00	1721.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence