iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118539

Ensembl Protein ID

ENSTRUP00000045537.1

UniProt Accession

H2V8J8; H2V8J8_TAKRU

Protein Name

Uncharacterized protein

Gene Name

llgl1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017766.1	ENSTRUT00000045690.1	ENSTRUP00000045536.1
ENSTRUG00000017766.1	ENSTRUT00000045691.1	ENSTRUP00000045537.1
ENSTRUG00000017766.1	ENSTRUT00000045692.1	ENSTRUP00000045538.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-08	35.2	78	108

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtg 33
            vt ++f ++ ++l+s  dD+ti++W+l  g
   Q: 78   AVTQIHFlPGqGRLLSLLDDNTIHLWELVAG 108
           49******999****************9766 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MMKFRFRRQG TDPQREKIKQ ELFAFNKTVE HGFPHQPSAL AFDPKLQLMA IGTKSGAIKM 60
VYGVPGVEFT GLHKDTTAVT QIHFLPGQGR LLSLLDDNTI HLWELVAGAP REVGGEKRDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGAAGT TTAGATTTCG TCGGCAGGGT ACTGACCCAC AGAGAGAGAA GATAAAACAG 60
GAGCTATTTG CCTTCAACAA GGTAAAGTAA CGGAACGCAG CGAGCGGACT CTTCTTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08366--LLGL
PF00400--WD40

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0003407--P:neural retina development
GO:0048919--P:posterior lateral line neuromast development
GO:0017157--P:regulation of exocytosis
GO:0008593--P:regulation of Notch signaling pathway
GO:0050708--P:regulation of protein secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001841	Ailuropoda melanoleuca	65.98	0.00e+00	1185.00
IUUC-Apl-003619	Anas platyrhynchos	55.99	0.00e+00	995.00
IUUC-Aca-005314	Anolis carolinensis	69.73	0.00e+00	1283.00
IUUC-Ame-011869	Astyanax mexicanus	76.08	0.00e+00	1469.00
IUUC-Bta-013086	Bos taurus	64.74	0.00e+00	1281.00
IUUC-Cja-019964	Callithrix jacchus	65.37	0.00e+00	1230.00
IUUC-Cfa-021081	Canis familiaris	68.44	0.00e+00	1277.00
IUUC-Cpo-022226	Cavia porcellus	64.67	0.00e+00	1144.00
IUUC-Csa-023680	Chlorocebus sabaeus	65.98	0.00e+00	1250.00
IUUC-Cin-025693	Ciona intestinalis	47.49	0.00e+00	776.00
IUUC-Csv-025981	Ciona savignyi	49.80	0.00e+00	894.00
IUUC-Dre-027684	Danio rerio	74.54	0.00e+00	1425.00
IUUC-Dno-028910	Dasypus novemcinctus	57.50	0.00e+00	989.00
IUUC-Dor-030545	Dipodomys ordii	65.74	0.00e+00	1262.00
IUUC-Ete-033043	Echinops telfairi	59.85	1.00e-147	517.00
IUUC-Eca-034305	Equus caballus	66.03	0.00e+00	1211.00
IUUC-Eeu-035274	Erinaceus europaeus	56.16	0.00e+00	940.00
IUUC-Fca-035636	Felis catus	66.94	0.00e+00	1222.00
IUUC-Fal-037109	Ficedula albicollis	68.70	0.00e+00	1266.00
IUUC-Gmo-039657	Gadus morhua	82.39	0.00e+00	1217.00
IUUC-Gga-040497	Gallus gallus	69.03	0.00e+00	1306.00
IUUC-Gac-041546	Gasterosteus aculeatus	88.44	0.00e+00	1668.00
IUUC-Ggo-045291	Gorilla gorilla	65.98	0.00e+00	1231.00
IUUC-Hsa-046004	Homo sapiens	66.09	0.00e+00	1233.00
IUUC-Itr-048031	Ictidomys tridecemlineatus	66.14	0.00e+00	1214.00
IUUC-Lch-049832	Latimeria chalumnae	67.36	0.00e+00	1184.00
IUUC-Loc-052641	Lepisosteus oculatus	74.59	0.00e+00	1413.00
IUUC-Laf-054218	Loxodonta africana	65.17	0.00e+00	1143.00
IUUC-Mcc-055013	Macaca mulatta	65.78	0.00e+00	1244.00
IUUC-Mga-060026	Meleagris gallopavo	66.35	0.00e+00	1173.00
IUUC-Mmr-060930	Microcebus murinus	56.27	0.00e+00	962.00
IUUC-Mdo-062135	Monodelphis domestica	71.06	0.00e+00	1325.00
IUUC-Mmu-063168	Mus musculus	66.39	0.00e+00	1230.00
IUUC-Mpu-066685	Mustela putorius furo	67.05	0.00e+00	1232.00
IUUC-Mlu-067389	Myotis lucifugus	65.61	0.00e+00	1252.00
IUUC-Nle-069136	Nomascus leucogenys	56.22	0.00e+00	997.00
IUUC-Opr-070896	Ochotona princeps	65.51	0.00e+00	1229.00
IUUC-Ont-071498	Oreochromis niloticus	90.20	0.00e+00	1656.00
IUUC-Oan-073365	Ornithorhynchus anatinus	69.83	0.00e+00	1257.00
IUUC-Ocu-074863	Oryctolagus cuniculus	56.85	0.00e+00	990.00
IUUC-Ola-086914	Oryzias latipes	86.38	0.00e+00	1605.00
IUUC-Oga-088401	Otolemur garnettii	66.91	0.00e+00	1251.00
IUUC-Oar-089232	Ovis aries	63.48	0.00e+00	1244.00
IUUC-Ptr-090647	Pan troglodytes	65.33	0.00e+00	1179.00
IUUC-Pan-092339	Papio anubis	65.78	0.00e+00	1245.00
IUUC-Psi-093016	Pelodiscus sinensis	62.28	0.00e+00	1036.00
IUUC-Pfo-096941	Poecilia formosa	88.66	0.00e+00	1661.00
IUUC-Pab-098102	Pongo abelii	65.52	0.00e+00	1210.00
IUUC-Pva-102768	Pteropus vampyrus	66.67	0.00e+00	1280.00
IUUC-Rno-105033	Rattus norvegicus	67.01	0.00e+00	1281.00
IUUC-Sha-106592	Sarcophilus harrisii	54.38	0.00e+00	937.00
IUUC-Sar-113145	Sorex araneus	63.10	0.00e+00	801.00
IUUC-Tgu-117381	Taeniopygia guttata	55.69	0.00e+00	989.00
IUUC-Tsy-119013	Tarsius syrichta	58.20	6.00e-176	611.00
IUUC-Tbe-127984	Tupaia belangeri	50.92	6.00e-142	498.00
IUUC-Ttr-128232	Tursiops truncatus	65.07	0.00e+00	1207.00
IUUC-Xtr-132060	Xenopus tropicalis	70.14	0.00e+00	1349.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence