iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000010389.3	ENSMMUT00000014535.3	ENSMMUP00000013617.3
ENSMMUG00000010389.3	ENSMMUT00000014541.3	ENSMMUP00000013623.3
ENSMMUG00000010389.3	ENSMMUT00000014539.3	ENSMMUP00000013621.3
ENSMMUG00000010389.3	ENSMMUT00000044690.2	ENSMMUP00000037706.2
ENSMMUG00000010389.3	ENSMMUT00000014542.3	ENSMMUP00000013624.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-14	54.5	92	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgti 25
           gH + +++ +f    +d+ +vs+s+Dg+i
   Q: 92   GHRANIFSAKFlpctNDKQIVSCSGDGVI 120
           8************9777**********98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSRGGSCPHL LWDVRKRSLG LEDPSRLRSR YLGRREFIQR LKLEATLNVH DGCVNTICWN 60
DTGEYILSGS DDTKLVISNP YSRKVLTTIR SGHRANIFSA KFLPCTNDKQ IVSCSGDGVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCGGG GTGGCTCCTG CCCACACCTG TTGTGGGACG TGAGGAAAAG GTCCCTTGGG 60
CTGGAGGACC CGTCCCGGCT GCGGAGCCGC TACCTGGGTG AGCGGGGGCC CCGGGGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	91.96	0.00e+00	1585.00
IUUC-Apl-003181	Anas platyrhynchos	87.02	0.00e+00	718.00
IUUC-Aca-004953	Anolis carolinensis	70.29	0.00e+00	1183.00
IUUC-Acl-008211	Aspergillus clavatus	27.64	3.00e-27	117.00
IUUC-Afu-008828	Aspergillus fumigatus	28.05	6.00e-28	120.00
IUUC-Ate-010555	Aspergillus terreus	25.85	2.00e-25	111.00
IUUC-Ame-011314	Astyanax mexicanus	85.47	0.00e+00	670.00
IUUC-Bta-013552	Bos taurus	84.13	0.00e+00	1466.00
IUUC-Cja-019015	Callithrix jacchus	97.29	0.00e+00	1647.00
IUUC-Cfa-021249	Canis familiaris	93.22	0.00e+00	1570.00
IUUC-Cpo-021903	Cavia porcellus	94.62	0.00e+00	1007.00
IUUC-Csa-023744	Chlorocebus sabaeus	97.29	0.00e+00	1652.00
IUUC-Cho-024527	Choloepus hoffmanni	78.05	0.00e+00	1210.00
IUUC-Dre-028040	Danio rerio	86.16	0.00e+00	668.00
IUUC-Dno-029777	Dasypus novemcinctus	92.71	0.00e+00	1570.00
IUUC-Dor-030879	Dipodomys ordii	77.77	0.00e+00	1299.00
IUUC-Ete-032607	Echinops telfairi	71.28	0.00e+00	1017.00
IUUC-Eca-033396	Equus caballus	96.73	0.00e+00	766.00
IUUC-Eeu-034944	Erinaceus europaeus	63.77	0.00e+00	703.00
IUUC-Fca-036020	Felis catus	87.89	0.00e+00	1464.00
IUUC-Fal-037527	Ficedula albicollis	91.58	0.00e+00	743.00
IUUC-Gmo-039347	Gadus morhua	83.19	0.00e+00	639.00
IUUC-Gga-040564	Gallus gallus	88.70	0.00e+00	754.00
IUUC-Gac-042029	Gasterosteus aculeatus	84.46	0.00e+00	651.00
IUUC-Ggo-045634	Gorilla gorilla	93.16	0.00e+00	668.00
IUUC-Hsa-045743	Homo sapiens	99.13	0.00e+00	870.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	96.73	0.00e+00	799.00
IUUC-Lch-050457	Latimeria chalumnae	71.47	0.00e+00	1194.00
IUUC-Loc-052880	Lepisosteus oculatus	87.22	0.00e+00	669.00
IUUC-Lma-053032	Leptosphaeria maculans	29.74	7.00e-28	119.00
IUUC-Laf-053836	Loxodonta africana	94.35	0.00e+00	821.00
IUUC-Mga-059293	Meleagris gallopavo	83.26	0.00e+00	643.00
IUUC-Mmr-060923	Microcebus murinus	95.09	0.00e+00	1600.00
IUUC-Mdo-063056	Monodelphis domestica	76.35	0.00e+00	1269.00
IUUC-Mmu-063121	Mus musculus	92.17	0.00e+00	869.00
IUUC-Mpu-066035	Mustela putorius furo	87.37	0.00e+00	1383.00
IUUC-Mlu-067903	Myotis lucifugus	91.90	0.00e+00	811.00
IUUC-Nfi-068606	Neosartorya fischeri	27.76	2.00e-27	118.00
IUUC-Nle-069415	Nomascus leucogenys	98.06	0.00e+00	1556.00
IUUC-Opr-070809	Ochotona princeps	71.66	8.00e-148	518.00
IUUC-Ont-071470	Oreochromis niloticus	84.46	0.00e+00	650.00
IUUC-Oan-072748	Ornithorhynchus anatinus	89.85	1.00e-131	462.00
IUUC-Ocu-073865	Oryctolagus cuniculus	92.77	0.00e+00	786.00
IUUC-Ola-086755	Oryzias latipes	83.33	0.00e+00	645.00
IUUC-Oga-088309	Otolemur garnettii	87.16	0.00e+00	1477.00
IUUC-Oar-090264	Ovis aries	93.01	0.00e+00	1568.00
IUUC-Ptr-090603	Pan troglodytes	98.33	0.00e+00	1638.00
IUUC-Pan-092480	Papio anubis	99.57	0.00e+00	885.00
IUUC-Psi-092973	Pelodiscus sinensis	73.44	1.00e-141	496.00
IUUC-Pfo-096506	Poecilia formosa	83.90	0.00e+00	645.00
IUUC-Pab-097581	Pongo abelii	84.03	0.00e+00	1395.00
IUUC-Pca-100155	Procavia capensis	74.11	0.00e+00	1261.00
IUUC-Pva-103022	Pteropus vampyrus	84.23	0.00e+00	1368.00
IUUC-Pte-104187	Pyrenophora teres	30.00	2.00e-28	122.00
IUUC-Pyt-104546	Pyrenophora triticirepentis	30.00	2.00e-27	118.00
IUUC-Rno-105851	Rattus norvegicus	87.08	0.00e+00	1568.00
IUUC-Sha-106790	Sarcophilus harrisii	84.03	0.00e+00	779.00
IUUC-Sja-107779	Schizosaccharomyces japonicus	32.59	6.00e-35	142.00
IUUC-Spo-108129	Schizosaccharomyces pombe	31.86	1.00e-33	138.00
IUUC-Ssc-115801	Sus scrofa	78.55	8.00e-121	426.00
IUUC-Tgu-116760	Taeniopygia guttata	90.21	0.00e+00	687.00
IUUC-Tru-118422	Takifugu rubripes	65.87	0.00e+00	711.00
IUUC-Tni-120340	Tetraodon nigroviridis	84.57	0.00e+00	642.00
IUUC-Tbe-127997	Tupaia belangeri	70.70	0.00e+00	1096.00
IUUC-Ttr-129311	Tursiops truncatus	86.46	0.00e+00	1436.00
IUUC-Vpa-130145	Vicugna pacos	92.22	0.00e+00	1458.00
IUUC-Xtr-132496	Xenopus tropicalis	81.38	0.00e+00	669.00
IUUC-Xma-133610	Xiphophorus maculatus	84.75	0.00e+00	648.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence