iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059250

Ensembl Protein ID

ENSMGAP00000012803.2

UniProt Accession

G1NHW7; G1NHW7_MELGA

Protein Name

Uncharacterized protein

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000012170.2	ENSMGAT00000013701.2	ENSMGAP00000012803.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	81.08	0.00e+00	1945.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

SDFGSLFDLE HDLPDELISS TELGLTNGGD INQLQTSLGL AQDAASKHKQ LSELLRAGSS 60
PNLNMGVGGP GQGMAGQTPQ NSPGMGMLNS MVKSPMAQAG LTSPSMAMGT SGPNQGPSAQ 120

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Nucleotide Sequence
(Fasta)

TCAGATTTTG GATCGCTATT TGATCTGGAA CATGACTTGC CAGATGAACT GATCAGCTCC 60
ACAGAACTGG GACTCACCAA TGGTGGTGAC ATTAATCAGC TGCAGACCAG CCTTGGCCTG 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002027	Ailuropoda melanoleuca	81.87	0.00e+00	1736.00
IUUC-Aca-005040	Anolis carolinensis	81.20	0.00e+00	1938.00
IUUC-Ame-011395	Astyanax mexicanus	79.96	0.00e+00	1492.00
IUUC-Bta-012649	Bos taurus	79.22	0.00e+00	1807.00
IUUC-Cel-018691	Caenorhabditis elegans	49.94	0.00e+00	845.00
IUUC-Cja-019649	Callithrix jacchus	79.26	0.00e+00	1885.00
IUUC-Cfa-020764	Canis familiaris	89.75	0.00e+00	1633.00
IUUC-Cpo-022345	Cavia porcellus	79.57	0.00e+00	1837.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	35.09	2.00e-65	244.00
IUUC-Csa-023866	Chlorocebus sabaeus	81.24	0.00e+00	1843.00
IUUC-Cho-024951	Choloepus hoffmanni	89.58	0.00e+00	1159.00
IUUC-Csv-026122	Ciona savignyi	65.15	0.00e+00	679.00
IUUC-Dre-028500	Danio rerio	79.74	0.00e+00	1488.00
IUUC-Ete-032979	Echinops telfairi	76.35	0.00e+00	1574.00
IUUC-Eca-034048	Equus caballus	84.28	0.00e+00	1712.00
IUUC-Fca-035891	Felis catus	82.72	0.00e+00	1843.00
IUUC-Fal-037585	Ficedula albicollis	91.50	0.00e+00	3373.00
IUUC-Gmo-039348	Gadus morhua	84.78	0.00e+00	1450.00
IUUC-Gga-040916	Gallus gallus	95.86	0.00e+00	2161.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.34	0.00e+00	1415.00
IUUC-Ggo-045189	Gorilla gorilla	81.51	0.00e+00	1838.00
IUUC-Hsa-046884	Homo sapiens	81.37	0.00e+00	1843.00
IUUC-Hvu-047619	Hordeum vulgare	37.66	7.00e-68	252.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	83.04	0.00e+00	1773.00
IUUC-Laf-054423	Loxodonta africana	79.97	0.00e+00	1936.00
IUUC-Mcc-054847	Macaca mulatta	80.90	0.00e+00	1850.00
IUUC-Meu-056217	Macropus eugenii	79.97	0.00e+00	1880.00
IUUC-Mtr-058740	Medicago truncatula	38.52	1.00e-68	255.00
IUUC-Mmr-061496	Microcebus murinus	81.78	0.00e+00	1844.00
IUUC-Mdo-062478	Monodelphis domestica	81.80	0.00e+00	2026.00
IUUC-Mmu-063456	Mus musculus	82.39	0.00e+00	1707.00
IUUC-Mac-064767	Musa acuminata	40.10	1.00e-76	281.00
IUUC-Mpu-065963	Mustela putorius furo	81.89	0.00e+00	1709.00
IUUC-Mlu-067185	Myotis lucifugus	83.36	0.00e+00	1697.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	70.90
IUUC-Nle-069907	Nomascus leucogenys	83.92	0.00e+00	1689.00
IUUC-Opr-070324	Ochotona princeps	71.73	0.00e+00	967.00
IUUC-Ont-072211	Oreochromis niloticus	79.35	0.00e+00	1482.00
IUUC-Oan-073723	Ornithorhynchus anatinus	89.95	0.00e+00	1874.00
IUUC-Ocu-074707	Oryctolagus cuniculus	83.41	0.00e+00	1701.00
IUUC-Oba-075590	Oryza barthii	33.89	3.00e-104	374.00
IUUC-Ogu-078580	Oryza glumaepatula	33.75	2.00e-104	374.00
IUUC-Oin-079283	Oryza indica	39.34	3.00e-74	274.00
IUUC-Ome-081615	Oryza meridionalis	33.89	3.00e-104	373.00
IUUC-Oni-082636	Oryza nivara	33.89	2.00e-104	374.00
IUUC-Opu-084073	Oryza punctata	39.34	9.00e-75	275.00
IUUC-Oru-084994	Oryza rufipogon	33.89	2.00e-104	374.00
IUUC-Osa-085860	Oryza sativa	42.26	5.00e-63	236.00
IUUC-Olu-087701	Ostreococcus lucimarinus	35.44	5.00e-63	236.00
IUUC-Oga-088700	Otolemur garnettii	79.56	0.00e+00	1844.00
IUUC-Oar-089787	Ovis aries	83.73	0.00e+00	1741.00
IUUC-Ptr-091620	Pan troglodytes	80.50	0.00e+00	1840.00
IUUC-Pan-092166	Papio anubis	80.03	0.00e+00	1873.00
IUUC-Psi-093992	Pelodiscus sinensis	91.47	0.00e+00	1982.00
IUUC-Ppa-095569	Physcomitrella patens	38.23	5.00e-72	266.00
IUUC-Pfo-097342	Poecilia formosa	76.81	0.00e+00	1392.00
IUUC-Pab-098235	Pongo abelii	80.09	0.00e+00	1837.00
IUUC-Pop-098947	Populus trichocarpa	40.51	1.00e-74	275.00
IUUC-Pca-100780	Procavia capensis	83.55	0.00e+00	1389.00
IUUC-Pva-103071	Pteropus vampyrus	80.97	0.00e+00	1919.00
IUUC-Sha-106736	Sarcophilus harrisii	92.88	0.00e+00	1667.00
IUUC-Smo-109420	Selaginella moellendorffii	38.01	1.00e-71	265.00
IUUC-Sar-113162	Sorex araneus	79.95	0.00e+00	731.00
IUUC-Ssc-116077	Sus scrofa	79.31	0.00e+00	1855.00
IUUC-Tgu-116872	Taeniopygia guttata	90.17	0.00e+00	3352.00
IUUC-Tru-118047	Takifugu rubripes	81.18	0.00e+00	1475.00
IUUC-Tsy-119451	Tarsius syrichta	78.03	0.00e+00	1221.00
IUUC-Tca-121835	Theobroma cacao	39.65	4.00e-74	273.00
IUUC-Tur-126284	Triticum urartu	37.91	2.00e-68	254.00
IUUC-Tbe-127772	Tupaia belangeri	73.96	0.00e+00	1189.00
IUUC-Vpa-130766	Vicugna pacos	88.77	0.00e+00	1132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence