iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003179

Ensembl Protein ID

ENSAPLP00000000450.1

UniProt Accession

U3HZN0; U3HZN0_ANAPL

Genbank Protein ID

ENSAPLP00000000450

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01126890

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000000756.1	ENSAPLT00000001018.1	ENSAPLP00000000450.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-43	143.7	230	268
UBD/Beta-Prp	4.10e-76	255.7	13	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v  +af +d t++vs+s D+++kvWD  t ++++
   Q: 230  GHGSWVLNVAFcPDdTHFVSSSSDKSVKVWDAGTRTCVH 268
           8***********777****************88877776 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
           ++h++ i +v++    +++++++++gs d+ +kvw++  +kl   ++l+gh+ +v +v++s++g+i +++s D++i++wdl+tgk++ +
   Q: 13   QAHDDDIWSVAWgknkKDGSEIVISGSLDDLVKVWKWNGEKLnlQWTLEGHQLGVVSVDISHTGSIAASSSLDAHIRLWDLETGKQIKS 101
           555556666888888788899*******************999899******************************************* PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           + +   +++sl+fsp++++l++Gsh+  ++++  etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g 
   Q: 102  IDAGPVDAWSLAFSPDSQYLATGSHVGKVNIFGAETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG- 188
           *****************************************.*********************************************9. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd  ++++++t++ h+++v
   Q: 189  HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLNVAFCPDDTHFVSSSSDKSVKVWDAGTRTCVHTFSDHQDQV 277
           ***************************************************************************************** PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           + v++ + +++++v++++d++++i+++
   Q: 278  WGVKY-NGSGSKIVSVGNDKEIHIYDC 303
           *****.999****************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MTTQYGILFK QEQAHDDDIW SVAWGKNKKD GSEIVISGSL DDLVKVWKWN GEKLNLQWTL 60
EGHQLGVVSV DISHTGSIAA SSSLDAHIRL WDLETGKQIK SIDAGPVDAW SLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCCAGAG CATTCCTGTT AAGATTGCTT CCATAAAGAC ATGACCACGC AGGTAAATGA 60
GAACTTAATT TTAAGTGAAG TAATTGTTGG TTTGATATAT ATACTATATA TATATATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

apla:101801412

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	33.63	9.00e-47	180.00
IUUC-Aml-002245	Ailuropoda melanoleuca	90.82	3.00e-155	540.00
IUUC-Atr-003142	Amborella trichopoda	51.55	2.00e-38	151.00
IUUC-Aca-004880	Anolis carolinensis	89.18	2.00e-157	547.00
IUUC-Aly-005956	Arabidopsis lyrata	38.02	9.00e-58	216.00
IUUC-Ath-007230	Arabidopsis thaliana	37.82	2.00e-52	198.00
IUUC-Acl-008297	Aspergillus clavatus	29.43	7.00e-26	111.00
IUUC-Ame-011511	Astyanax mexicanus	84.36	3.00e-149	520.00
IUUC-Bgr-012189	Blumeria graminis	30.67	1.00e-30	126.00
IUUC-Bta-012936	Bos taurus	91.15	3.00e-155	540.00
IUUC-Bdi-015020	Brachypodium distachyon	36.86	8.00e-47	180.00
IUUC-Bol-015927	Brassica oleracea	38.98	2.00e-58	218.00
IUUC-Bra-017323	Brassica rapa	38.02	3.00e-58	218.00
IUUC-Cja-019961	Callithrix jacchus	91.15	1.00e-155	541.00
IUUC-Cfa-020862	Canis familiaris	90.49	4.00e-154	536.00
IUUC-Cpo-021356	Cavia porcellus	90.73	4.00e-153	533.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.25	2.00e-56	212.00
IUUC-Csa-024067	Chlorocebus sabaeus	90.82	7.00e-155	539.00
IUUC-Cho-024421	Choloepus hoffmanni	78.28	3.00e-78	283.00
IUUC-Cin-025261	Ciona intestinalis	63.93	3.00e-116	410.00
IUUC-Cne-026846	Cryptococcus neoformans	28.52	4.00e-23	101.00
IUUC-Dre-027706	Danio rerio	65.25	9.00e-110	389.00
IUUC-Dno-029084	Dasypus novemcinctus	90.23	1.00e-153	535.00
IUUC-Dor-030353	Dipodomys ordii	77.17	1.00e-113	402.00
IUUC-Dse-031348	Dothistroma septosporum	28.76	6.00e-28	117.00
IUUC-Dme-031836	Drosophila melanogaster	51.08	6.00e-88	317.00
IUUC-Ete-032261	Echinops telfairi	89.18	2.00e-150	524.00
IUUC-Eca-034231	Equus caballus	82.95	3.00e-139	487.00
IUUC-Eeu-034828	Erinaceus europaeus	89.69	3.00e-144	503.00
IUUC-Fca-036569	Felis catus	91.15	8.00e-155	538.00
IUUC-Fal-037469	Ficedula albicollis	96.39	2.00e-164	571.00
IUUC-Fox-038047	Fusarium oxysporum	33.78	1.00e-29	123.00
IUUC-Gmo-039579	Gadus morhua	82.30	6.00e-144	503.00
IUUC-Gga-040808	Gallus gallus	96.92	5.00e-157	546.00
IUUC-Gac-042100	Gasterosteus aculeatus	85.25	5.00e-148	516.00
IUUC-Gma-043509	Glycine max	41.53	2.00e-61	229.00
IUUC-Ggo-045227	Gorilla gorilla	91.15	1.00e-155	541.00
IUUC-Hsa-045839	Homo sapiens	91.15	1.00e-155	541.00
IUUC-Hvu-047591	Hordeum vulgare	37.74	8.00e-49	186.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	90.82	5.00e-155	539.00
IUUC-Lch-049549	Latimeria chalumnae	82.62	1.00e-144	505.00
IUUC-Lpe-050746	Leersia perrieri	38.26	3.00e-48	184.00
IUUC-Loc-052540	Lepisosteus oculatus	86.23	2.00e-148	518.00
IUUC-Lma-052992	Leptosphaeria maculans	29.45	9.00e-28	117.00
IUUC-Laf-053907	Loxodonta africana	90.82	5.00e-155	539.00
IUUC-Mcc-055828	Macaca mulatta	85.23	2.00e-151	527.00
IUUC-Meu-056075	Macropus eugenii	94.47	4.00e-133	466.00
IUUC-Mor-056971	Magnaporthe oryzae	27.63	7.00e-25	107.00
IUUC-Mtr-057728	Medicago truncatula	41.35	5.00e-59	220.00
IUUC-Mga-059872	Meleagris gallopavo	97.05	1.00e-165	574.00
IUUC-Mvi-060564	Microbotryum violaceum	33.44	7.00e-32	130.00
IUUC-Mmr-060985	Microcebus murinus	91.44	4.00e-148	516.00
IUUC-Mdo-062758	Monodelphis domestica	89.47	1.00e-156	544.00
IUUC-Mmu-063580	Mus musculus	88.85	7.00e-153	532.00
IUUC-Mac-064880	Musa acuminata	39.87	3.00e-58	218.00
IUUC-Mpu-066577	Mustela putorius furo	90.49	4.00e-154	536.00
IUUC-Nle-069573	Nomascus leucogenys	91.15	1.00e-155	541.00
IUUC-Opr-070216	Ochotona princeps	90.37	1.00e-152	531.00
IUUC-Ont-071981	Oreochromis niloticus	85.25	4.00e-150	523.00
IUUC-Oan-073223	Ornithorhynchus anatinus	95.45	1.00e-108	384.00
IUUC-Ocu-074199	Oryctolagus cuniculus	78.03	8.00e-128	449.00
IUUC-Oba-075255	Oryza barthii	40.38	6.00e-42	163.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	142.00
IUUC-Ogl-077777	Oryza glaberrima	38.06	7.00e-49	187.00
IUUC-Ogu-078780	Oryza glumaepatula	38.06	7.00e-49	187.00
IUUC-Oin-079228	Oryza indica	38.06	2.00e-51	195.00
IUUC-Olo-080617	Oryza longistaminata	45.77	2.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.06	3.00e-48	185.00
IUUC-Oni-082997	Oryza nivara	38.06	2.00e-51	195.00
IUUC-Opu-083931	Oryza punctata	38.39	6.00e-49	187.00
IUUC-Oru-084645	Oryza rufipogon	38.06	7.00e-49	187.00
IUUC-Osa-085842	Oryza sativa	38.06	2.00e-51	195.00
IUUC-Ola-086696	Oryzias latipes	85.57	2.00e-146	511.00
IUUC-Olu-087643	Ostreococcus lucimarinus	40.38	4.00e-42	163.00
IUUC-Oga-088272	Otolemur garnettii	90.46	5.00e-153	533.00
IUUC-Oar-089416	Ovis aries	91.15	3.00e-155	540.00
IUUC-Ptr-090944	Pan troglodytes	91.15	1.00e-155	541.00
IUUC-Pan-091861	Papio anubis	91.15	1.00e-155	541.00
IUUC-Psi-093750	Pelodiscus sinensis	94.75	3.00e-162	563.00
IUUC-Pma-094608	Petromyzon marinus	80.65	2.00e-135	474.00
IUUC-Pno-094832	Phaeosphaeria nodorum	37.91	1.00e-26	113.00
IUUC-Ppa-095737	Physcomitrella patens	40.06	5.00e-58	217.00
IUUC-Pfo-096479	Poecilia formosa	86.56	3.00e-143	500.00
IUUC-Pab-098179	Pongo abelii	91.15	1.00e-155	541.00
IUUC-Pop-099532	Populus trichocarpa	41.61	2.00e-58	219.00
IUUC-Pca-100664	Procavia capensis	71.01	2.00e-97	348.00
IUUC-Ppe-102056	Prunus persica	39.94	7.00e-59	220.00
IUUC-Pva-102859	Pteropus vampyrus	90.82	4.00e-154	536.00
IUUC-Pte-104236	Pyrenophora teres	37.36	5.00e-26	111.00
IUUC-Rno-105826	Rattus norvegicus	88.52	4.00e-152	530.00
IUUC-Sha-106660	Sarcophilus harrisii	91.36	1.00e-149	521.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	34.21	4.00e-38	151.00
IUUC-Spo-108244	Schizosaccharomyces pombe	32.57	3.00e-36	144.00
IUUC-Smo-109234	Selaginella moellendorffii	42.81	8.00e-63	233.00
IUUC-Sit-110048	Setaria italica	36.77	2.00e-40	159.00
IUUC-Sly-111618	Solanum lycopersicum	38.34	2.00e-53	202.00
IUUC-Stu-112543	Solanum tuberosum	37.82	2.00e-56	212.00
IUUC-Sar-113743	Sorex araneus	71.80	1.00e-119	421.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	5.00e-42	164.00
IUUC-Ssc-115560	Sus scrofa	85.90	1.00e-143	501.00
IUUC-Tgu-117300	Taeniopygia guttata	96.72	5.00e-165	572.00
IUUC-Tru-117933	Takifugu rubripes	85.57	2.00e-149	521.00
IUUC-Tsy-119574	Tarsius syrichta	80.00	6.00e-131	459.00
IUUC-Tni-120191	Tetraodon nigroviridis	87.34	9.00e-113	398.00
IUUC-Tca-120983	Theobroma cacao	41.10	2.00e-59	222.00
IUUC-Tae-124056	Triticum aestivum	36.22	7.00e-49	187.00
IUUC-Tur-126711	Triticum urartu	36.10	2.00e-47	182.00
IUUC-Tme-127066	Tuber melanosporum	34.69	3.00e-35	142.00
IUUC-Tbe-127802	Tupaia belangeri	91.15	8.00e-155	538.00
IUUC-Ttr-128861	Tursiops truncatus	87.30	2.00e-50	191.00
IUUC-Vda-129720	Verticillium dahliae	31.64	4.00e-24	105.00
IUUC-Vpa-130618	Vicugna pacos	87.85	7.00e-125	439.00
IUUC-Vvi-130981	Vitis vinifera	41.03	4.00e-58	217.00
IUUC-Xtr-132460	Xenopus tropicalis	86.89	5.00e-148	516.00
IUUC-Xma-134154	Xiphophorus maculatus	86.56	2.00e-143	501.00
IUUC-Yli-134554	Yarrowia lipolytica	29.89	3.00e-23	101.00
IUUC-Zma-135097	Zea mays	36.69	2.00e-36	145.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence