iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000038713.6	ENSDART00000141784.1	ENSDARP00000117886.1
ENSDARG00000038713.6	ENSDART00000056536.5	ENSDARP00000056535.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-50	167.6	2114	2149
UBD/Beta-Prp	3.90e-84	283.3	1675	1912

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           H d++t++a+  s   ++s+s D+++++WD+ tg+ll+
   Q: 2114 HGDWITGCAWtlS--AVLSCSSDCKLRIWDIQTGNLLR 2149
           9*********432..59*****************9986 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           s  +cv +sp+++ +a+g   g + +  ++tg+ ++sl    ++++ + f  +++ l+ +s  + + vwd+ +++ + ++++h++++
   Q: 1675 SEPSCVVVSPGGKTIAVGTGEGALHLLHTETGQEVKSLLISGDGISGCIFLGEEN-LAMTSFNGEVEVWDIASSCRIAHINAHSNKI 1760
           5668999**********************************************97.5555566779********************* PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           + +++sp++  +++ s d  ++v+  ++++++  +l++     ncv+++ +g+ll+ G+ D++v lW+   +k + tl+g h++sv+
   Q: 1761 TGCDVSPDRRLFATVSLDLNLKVFSAQKNTEVA-CLENPC-PLNCVKFDLEGQLLAVGCWDGAVCLWNWLEQKKVATLQG-HESSVR 1844
           ********************************9.776554.79************************************9.****** PP
   S: 185  slsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           slsf++++  l sg l g v+lw++ +  cv ++++h+  ++s++f++ +++l+s+++D ++++W   
   Q: 1845 SLSFSHSSSILCSGCLSGEVRLWSVAAAACVGSFHAHRGSTQSLNFLQGGNFLLSAGQDSVVNVWSAG 1912
           *****************************************************************755 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MKAPALLQSD LKVNTDIRLQ QICHSPRLEN RILAQAASAL SHHQYAAPSW ASQTHISSAC 60
PALQPTSLSL TRSSSSLLSS TTMSSISSDS SLLSTKNTLL IEPRLHLPAS SSLTSTCSQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCGTCAA CAGCTCACCG GTTTACTTCA TTGTACACTA ATAATACATG GTCGCAAAGC 60
GTTAAAGGTA AGTTTTTGCC TTTATTTTTT TAGTCACGTC GTAATGAGTG TTTACAGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR025139--DUF4062
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0003723--F:RNA binding

KEGG

dre:561284

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	35.27	0.00e+00	1116.00
IUUC-Aca-005102	Anolis carolinensis	38.50	0.00e+00	1224.00
IUUC-Ame-011822	Astyanax mexicanus	58.16	0.00e+00	1476.00
IUUC-Bta-012323	Bos taurus	35.25	0.00e+00	1108.00
IUUC-Cja-019005	Callithrix jacchus	35.40	0.00e+00	1176.00
IUUC-Cfa-020803	Canis familiaris	34.89	0.00e+00	1029.00
IUUC-Cpo-022312	Cavia porcellus	35.09	0.00e+00	1099.00
IUUC-Csa-023287	Chlorocebus sabaeus	35.24	0.00e+00	1134.00
IUUC-Dno-029455	Dasypus novemcinctus	33.75	0.00e+00	1026.00
IUUC-Dor-030328	Dipodomys ordii	32.51	0.00e+00	723.00
IUUC-Ete-032385	Echinops telfairi	36.17	0.00e+00	739.00
IUUC-Eca-033726	Equus caballus	35.12	0.00e+00	1149.00
IUUC-Eeu-034665	Erinaceus europaeus	34.05	3.00e-92	335.00
IUUC-Fca-035365	Felis catus	34.92	0.00e+00	1126.00
IUUC-Gmo-039584	Gadus morhua	48.82	0.00e+00	916.00
IUUC-Gac-042307	Gasterosteus aculeatus	52.75	0.00e+00	1842.00
IUUC-Ggo-045432	Gorilla gorilla	33.53	0.00e+00	1065.00
IUUC-Hsa-046182	Homo sapiens	34.95	0.00e+00	1137.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	35.10	0.00e+00	1143.00
IUUC-Lch-050186	Latimeria chalumnae	38.52	2.00e-83	303.00
IUUC-Laf-054524	Loxodonta africana	34.97	0.00e+00	1162.00
IUUC-Mcc-055628	Macaca mulatta	35.13	0.00e+00	1137.00
IUUC-Meu-056338	Macropus eugenii	38.41	2.00e-106	382.00
IUUC-Mmr-060854	Microcebus murinus	35.36	0.00e+00	1152.00
IUUC-Mdo-062247	Monodelphis domestica	33.94	0.00e+00	1094.00
IUUC-Mmu-064406	Mus musculus	34.47	0.00e+00	1040.00
IUUC-Mpu-065806	Mustela putorius furo	35.63	0.00e+00	1155.00
IUUC-Mlu-068116	Myotis lucifugus	34.85	0.00e+00	1056.00
IUUC-Nle-069628	Nomascus leucogenys	34.88	0.00e+00	1117.00
IUUC-Opr-070242	Ochotona princeps	32.96	0.00e+00	755.00
IUUC-Oan-073598	Ornithorhynchus anatinus	34.21	2.00e-158	555.00
IUUC-Ocu-073933	Oryctolagus cuniculus	35.32	0.00e+00	1130.00
IUUC-Ola-086886	Oryzias latipes	51.45	0.00e+00	1992.00
IUUC-Oga-088609	Otolemur garnettii	34.76	0.00e+00	1107.00
IUUC-Oar-089957	Ovis aries	35.57	0.00e+00	1066.00
IUUC-Ptr-090577	Pan troglodytes	35.40	0.00e+00	1128.00
IUUC-Pan-092397	Papio anubis	35.10	0.00e+00	1124.00
IUUC-Pma-094373	Petromyzon marinus	33.61	6.00e-63	235.00
IUUC-Pfo-096497	Poecilia formosa	52.74	0.00e+00	1929.00
IUUC-Pab-098028	Pongo abelii	35.26	0.00e+00	1118.00
IUUC-Pca-101002	Procavia capensis	34.90	0.00e+00	647.00
IUUC-Pva-102144	Pteropus vampyrus	36.55	1.00e-167	585.00
IUUC-Rno-105828	Rattus norvegicus	34.29	0.00e+00	1074.00
IUUC-Sha-106469	Sarcophilus harrisii	34.49	0.00e+00	1097.00
IUUC-Sar-113035	Sorex araneus	32.96	3.00e-134	474.00
IUUC-Ssc-116122	Sus scrofa	34.46	0.00e+00	784.00
IUUC-Tru-118412	Takifugu rubripes	51.28	0.00e+00	2043.00
IUUC-Tsy-119257	Tarsius syrichta	32.78	5.00e-107	384.00
IUUC-Tni-120032	Tetraodon nigroviridis	51.96	7.00e-76	277.00
IUUC-Tbe-127312	Tupaia belangeri	40.74	1.00e-77	286.00
IUUC-Ttr-128335	Tursiops truncatus	34.72	0.00e+00	1009.00
IUUC-Xtr-132524	Xenopus tropicalis	35.65	0.00e+00	1124.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence