iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033726

Ensembl Protein ID

ENSECAP00000009299.1

UniProt Accession

F7AEG0; F7AEG0_HORSE

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000010629.1	ENSECAT00000011854.1	ENSECAP00000009299.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-52	173.8	2093	2128
UBD/Beta-Prp	1.60e-80	270.7	2008	2179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvll 36
           H d+vt++a+  d+llvs+s Dg++ +WD+ +g +l
   Q: 2093 HRDWVTGCAWtKDNLLVSCSSDGSVGLWDPESGQQL 2128
           9*********877****************9999775 PP

UBD/Beta-Prp

   S: 63   dgkilvtgseDrtikvw.........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghd 137
           ++++l+++seD t+++w           ++++c   l+ghe  v ++sfs +g +l++G++dr + +wd++t +       + + h+
   Q: 2008 SQELLASASEDFTVRLWprqlltlpqKAEDFPCATELRGHEGPVSCCSFSTDGGSLATGGRDRNLLCWDVRTPKAPVLicsFSACHR 2094
           4569*************666665555555*******************************************998766688999*** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdn 224
           ++v++ ++ + +nllvs+s D+ v lWd ++g+ l ++ g h+++v  +   +  +++vs+++dgt+k+wd q  e + +  +h+ +
   Q: 2095 DWVTGCAWTK-DNLLVSCSSDGSVGLWDPESGQQLGQFLG-HQSAVSAVVAVE--EHVVSVGRDGTLKVWDHQGVE-LTSIPAHSGP 2176
           ********99.9***************************9.******999888..69**************98555.7777777777 PP
   S: 225  vks 227
           +++
   Q: 2177 ISQ 2179
           665 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LPDLKTMEKP HGHVSAHPNI LSLENRCLST LPDLKTVEKP HGHVSSHPNV LSLENRCLAT 60
LPDLKTVEKP HGHVSAHPNV LSLENRCLAT LPILKSTVSA SALLQRLQTF HPVQADLCSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCTGACC TGAAGACCAT GGAGAAACCA CATGGGCATG TGTCTGCCCA CCCAAACATC 60
CTCTCCTTGG AGAACCGGTG CCTGTCCACA CTTCCTGACC TGAAGACCGT GGAGAAACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	82.34	0.00e+00	3994.00
IUUC-Aca-005102	Anolis carolinensis	43.01	0.00e+00	1694.00
IUUC-Ame-011822	Astyanax mexicanus	35.03	0.00e+00	649.00
IUUC-Bta-012323	Bos taurus	82.42	0.00e+00	4089.00
IUUC-Cja-019005	Callithrix jacchus	81.92	0.00e+00	4171.00
IUUC-Cfa-020803	Canis familiaris	75.21	0.00e+00	3570.00
IUUC-Cpo-022312	Cavia porcellus	74.97	0.00e+00	3532.00
IUUC-Csa-023287	Chlorocebus sabaeus	83.46	0.00e+00	4158.00
IUUC-Dre-028825	Danio rerio	35.05	0.00e+00	1174.00
IUUC-Dno-029455	Dasypus novemcinctus	81.01	0.00e+00	3913.00
IUUC-Dor-030328	Dipodomys ordii	74.51	0.00e+00	2595.00
IUUC-Ete-032385	Echinops telfairi	75.68	0.00e+00	1986.00
IUUC-Eeu-034665	Erinaceus europaeus	66.99	0.00e+00	987.00
IUUC-Fca-035365	Felis catus	84.16	0.00e+00	4134.00
IUUC-Gmo-039584	Gadus morhua	31.69	6.00e-120	426.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.92	0.00e+00	1032.00
IUUC-Ggo-045432	Gorilla gorilla	80.75	0.00e+00	3937.00
IUUC-Hsa-046182	Homo sapiens	82.75	0.00e+00	4156.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	80.90	0.00e+00	4046.00
IUUC-Lch-050186	Latimeria chalumnae	39.19	4.00e-80	291.00
IUUC-Laf-054524	Loxodonta africana	80.64	0.00e+00	4055.00
IUUC-Mcc-055628	Macaca mulatta	83.72	0.00e+00	4186.00
IUUC-Meu-056338	Macropus eugenii	64.45	0.00e+00	1329.00
IUUC-Mmr-060854	Microcebus murinus	82.76	0.00e+00	4126.00
IUUC-Mdo-062247	Monodelphis domestica	62.21	0.00e+00	2847.00
IUUC-Mmu-064406	Mus musculus	74.79	0.00e+00	3664.00
IUUC-Mpu-065806	Mustela putorius furo	81.78	0.00e+00	4064.00
IUUC-Mlu-068116	Myotis lucifugus	85.48	0.00e+00	4148.00
IUUC-Nle-069628	Nomascus leucogenys	83.09	0.00e+00	3702.00
IUUC-Opr-070242	Ochotona princeps	79.55	0.00e+00	2851.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.96	0.00e+00	1937.00
IUUC-Ocu-073933	Oryctolagus cuniculus	80.84	0.00e+00	3964.00
IUUC-Ola-086886	Oryzias latipes	35.19	0.00e+00	1076.00
IUUC-Oga-088609	Otolemur garnettii	80.39	0.00e+00	3970.00
IUUC-Oar-089957	Ovis aries	81.79	0.00e+00	3964.00
IUUC-Ptr-090577	Pan troglodytes	81.41	0.00e+00	4082.00
IUUC-Pan-092397	Papio anubis	83.03	0.00e+00	4171.00
IUUC-Pma-094373	Petromyzon marinus	35.05	2.00e-72	266.00
IUUC-Pfo-096497	Poecilia formosa	35.85	0.00e+00	1073.00
IUUC-Pab-098028	Pongo abelii	82.72	0.00e+00	4109.00
IUUC-Pca-101002	Procavia capensis	83.49	0.00e+00	1902.00
IUUC-Pva-102144	Pteropus vampyrus	78.53	0.00e+00	1810.00
IUUC-Rno-105828	Rattus norvegicus	74.17	0.00e+00	3669.00
IUUC-Sha-106469	Sarcophilus harrisii	62.06	0.00e+00	2903.00
IUUC-Sar-113035	Sorex araneus	72.76	0.00e+00	2085.00
IUUC-Ssc-116122	Sus scrofa	84.50	0.00e+00	3086.00
IUUC-Tru-118412	Takifugu rubripes	32.57	0.00e+00	1161.00
IUUC-Tsy-119257	Tarsius syrichta	75.48	0.00e+00	1593.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.33	1.00e-39	156.00
IUUC-Tbe-127312	Tupaia belangeri	68.01	0.00e+00	1003.00
IUUC-Ttr-128335	Tursiops truncatus	80.85	0.00e+00	4040.00
IUUC-Xtr-132524	Xenopus tropicalis	39.88	0.00e+00	1405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence