iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054524

UUCD1 version

UUC-LoA-00078

Ensembl Protein ID

ENSLAFP00000002081.3

UniProt Accession

G3SQJ9; G3SQJ9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000002487.3	ENSLAFT00000002491.3	ENSLAFP00000002081.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-52	171.7	2088	2124
UBD/Beta-Prp	6.60e-97	324.6	1962	2173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllk 37
           H d+vt++a+  d+ll+s+s Dg++ +WD+ +g +l+
   Q: 2088 HRDWVTGCAWtRDNLLISCSSDGSVGLWDPESGQQLR 2124
           9*********988*****************9999886 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvw.........dlstgkcvhtlkghedsv 97
            ++l++g +dg+++ w +++ ++  l+ ls+ +++v  +  s++  +l+++seD t+++w           + ++c + l+ghe  v
   Q: 1962 PEVLVSGAEDGSLQGWAFKKSSVqsLWLLSKYQKPVLGLATSQE--LLASVSEDFTVRLWprglltlpqKAEEFPCGIELRGHEGPV 2046
           34566666666666666666666777777888888888888888..78888888888888777777666666888888888888888 PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
            ++sfs +g +l++G++dr + +wd++t +       + + h+++v++ ++   +nll+s+s D+ v lWd ++g+ lr++ g h++
   Q: 2047 NCCSFSTDGGSLATGGRDRSLLCWDVRTPSAPVLirsFSACHRDWVTGCAWTR-DNLLISCSSDGSVGLWDPESGQQLRQFLG-HQS 2131
           88888888888888888888888888887654444557788888888888887.78888888888888888888888888887.888 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           +v  ++  +  +++vs+++dgt+k+wd q  e + +  +h+ +++
   Q: 2132 AVSAVAAVE--EHVVSVGRDGTLKVWDHQGVE-LTSIPAHSGPIS 2173
           888888777..578888888888888877444.555556655555 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEKPHGHVSA YPDILSLENR CLVTFLDTKT MEKPHGRVSA HPDILSLENR CLATCPDVKS 60
MEKPRGHVSA HPDILSLENR CLATLPSLKS TMSASTLLQH LQIPHLAQAD LYSLNTNNSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAGC CACATGGGCA TGTGTCTGCA TACCCCGACA TCCTCTCCTT GGAGAACCGG 60
TGCCTGGTGA CATTTCTTGA CACGAAGACC ATGGAGAAGC CTCATGGGCG TGTGTCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR011041--Quinoprot_gluc/sorb_DH
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	75.90	0.00e+00	3662.00
IUUC-Aca-005102	Anolis carolinensis	42.08	0.00e+00	1605.00
IUUC-Ame-011822	Astyanax mexicanus	33.83	9.00e-174	605.00
IUUC-Bta-012323	Bos taurus	77.92	0.00e+00	3777.00
IUUC-Cja-019005	Callithrix jacchus	77.89	0.00e+00	3933.00
IUUC-Cfa-020803	Canis familiaris	69.89	0.00e+00	3264.00
IUUC-Cpo-022312	Cavia porcellus	71.27	0.00e+00	3337.00
IUUC-Csa-023287	Chlorocebus sabaeus	79.00	0.00e+00	3937.00
IUUC-Dre-028825	Danio rerio	34.84	0.00e+00	1149.00
IUUC-Dno-029455	Dasypus novemcinctus	79.12	0.00e+00	3777.00
IUUC-Dor-030328	Dipodomys ordii	70.42	0.00e+00	2468.00
IUUC-Ete-032385	Echinops telfairi	76.22	0.00e+00	1969.00
IUUC-Eca-033726	Equus caballus	80.64	0.00e+00	3972.00
IUUC-Eeu-034665	Erinaceus europaeus	64.17	0.00e+00	947.00
IUUC-Fca-035365	Felis catus	77.63	0.00e+00	3796.00
IUUC-Gmo-039584	Gadus morhua	32.38	6.00e-97	349.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.75	0.00e+00	1023.00
IUUC-Ggo-045432	Gorilla gorilla	76.70	0.00e+00	3697.00
IUUC-Hsa-046182	Homo sapiens	78.82	0.00e+00	3912.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	76.51	0.00e+00	3800.00
IUUC-Lch-050186	Latimeria chalumnae	39.63	3.00e-81	295.00
IUUC-Mcc-055628	Macaca mulatta	79.33	0.00e+00	3949.00
IUUC-Meu-056338	Macropus eugenii	63.08	0.00e+00	1280.00
IUUC-Mmr-060854	Microcebus murinus	78.42	0.00e+00	3835.00
IUUC-Mdo-062247	Monodelphis domestica	61.14	0.00e+00	2741.00
IUUC-Mmu-064406	Mus musculus	71.11	0.00e+00	3457.00
IUUC-Mpu-065806	Mustela putorius furo	76.48	0.00e+00	3760.00
IUUC-Mlu-068116	Myotis lucifugus	79.73	0.00e+00	3815.00
IUUC-Nle-069628	Nomascus leucogenys	79.34	0.00e+00	3519.00
IUUC-Opr-070242	Ochotona princeps	75.09	0.00e+00	2691.00
IUUC-Oan-073598	Ornithorhynchus anatinus	51.97	0.00e+00	1938.00
IUUC-Ocu-073933	Oryctolagus cuniculus	76.98	0.00e+00	3713.00
IUUC-Ola-086886	Oryzias latipes	34.73	0.00e+00	1053.00
IUUC-Oga-088609	Otolemur garnettii	76.05	0.00e+00	3692.00
IUUC-Oar-089957	Ovis aries	76.90	0.00e+00	3660.00
IUUC-Ptr-090577	Pan troglodytes	77.56	0.00e+00	3839.00
IUUC-Pan-092397	Papio anubis	78.65	0.00e+00	3915.00
IUUC-Pma-094373	Petromyzon marinus	35.52	9.00e-81	294.00
IUUC-Pfo-096497	Poecilia formosa	36.05	0.00e+00	1099.00
IUUC-Pab-098028	Pongo abelii	78.95	0.00e+00	3885.00
IUUC-Pca-101002	Procavia capensis	86.31	0.00e+00	1980.00
IUUC-Pva-102144	Pteropus vampyrus	74.22	0.00e+00	1667.00
IUUC-Rno-105828	Rattus norvegicus	71.26	0.00e+00	3493.00
IUUC-Sha-106469	Sarcophilus harrisii	60.94	0.00e+00	2827.00
IUUC-Sar-113035	Sorex araneus	68.03	0.00e+00	1961.00
IUUC-Ssc-116122	Sus scrofa	79.27	0.00e+00	2859.00
IUUC-Tru-118412	Takifugu rubripes	34.16	0.00e+00	1111.00
IUUC-Tsy-119257	Tarsius syrichta	73.94	0.00e+00	1549.00
IUUC-Tni-120032	Tetraodon nigroviridis	34.98	3.00e-40	158.00
IUUC-Tbe-127312	Tupaia belangeri	65.72	0.00e+00	954.00
IUUC-Ttr-128335	Tursiops truncatus	75.78	0.00e+00	3725.00
IUUC-Xtr-132524	Xenopus tropicalis	38.44	0.00e+00	1328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence