iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000135722.8	ENST00000258200.7	ENSP00000258200.3
ENSG00000135722.8	ENST00000519945.5	ENSP00000429684.1
ENSG00000135722.8	ENST00000517382.5	ENSP00000430745.1
ENSG00000135722.8	ENST00000521920.5	ENSP00000427895.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	miRTarBase	microRNA	TRANSFAC
RepTar	miRcode	RAID2
Protein-protein Interaction
InWeb_IM
Disease-associated Variation
GWASdb	OMIM
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	4.50e-06	28.5	5	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 103  ldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           ++ lpee+l  i+++l+ ++  +aarvcr w  +a  +a+w++ 
   Q: 5    GEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDT 48
           5679****************************99999****986 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAEPGEGLPE EVLALIFRHL SLRDRAAAAR VCRAWAAAAT CSAVWHDTKI RRPTRSVLDT 60
LPPSLASTPL RTLQLRGPGA GRGRARARAG PQGTCPAHTR SRTGDFSCRT KKEIEGPRGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTAGCCCGA GCCGCCCCGT CCGCCCGCGC GTCCCGCCCC GCGGGCTCCC GGTGGCTGCT 60
TCCCGTCCGC TGTCCTCTGC TGCCAGTCCC CTGCCCCGGG CAAAGCCCAT CTGGTCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012327	Bos taurus	90.91	8.00e-05	41.60
IUUC-Cja-019275	Callithrix jacchus	90.00	2.00e-09	56.60
IUUC-Dor-030117	Dipodomys ordii	85.42	6.00e-05	42.00
IUUC-Eeu-034813	Erinaceus europaeus	65.67	4.00e-07	49.30
IUUC-Fca-035409	Felis catus	86.36	1.00e-04	39.70
IUUC-Mcc-054642	Macaca mulatta	94.12	3.00e-11	59.30
IUUC-Mmu-063155	Mus musculus	63.64	2.00e-04	37.00
IUUC-Ocu-074339	Oryctolagus cuniculus	84.00	4.00e-07	49.30
IUUC-Oga-089027	Otolemur garnettii	62.50	7.00e-08	51.60
IUUC-Pva-102347	Pteropus vampyrus	82.00	2.00e-05	43.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence