iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074274

Ensembl Protein ID

ENSOCUP00000015831.2

UniProt Accession

G1TFY4; G1TFY4_RABIT

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000024029.2	ENSOCUT00000029475.2	ENSOCUP00000015831.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-27	92.7	153	190
UBD/Beta-Prp	2.80e-55	187.6	495	759

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899***************997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtl 175
           ++++f   +   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  
   Q: 584  TAIKFAGHRdIQMISCGADKSIYF---RSAQQASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGS 669
           *******654899*******9976...333333334445332122222333456777788****************9888888888888 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrsgdll 257
           +g +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++ ++ ll
   Q: 670  QG-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNCMKQHLL 757
           98.999999999**************************************************************887766666666665 PP
   S: 258  kt 259
            +
   Q: 758  EM 759
           55 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLPS VMAGVPARKG QSSPPPAPAL CLRRRTRLSA APEDTVQNRV 60
SLEKVLGITA QNSSGLTCDP GTGHVAYLAG CVVVILNPKE NKQQHILNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TAGGGCCCGG AGGCTACGCG CGGAACGATG CAGTCGAGAA GCTGCCATCT 60
GTCATGGCGG GAGTTCCGGC GCGGAAGGGC CAGTCCTCTC CGCCCCCGGC CCCAGCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	80.64	0.00e+00	2284.00
IUUC-Aca-004935	Anolis carolinensis	70.85	0.00e+00	999.00
IUUC-Ath-007624	Arabidopsis thaliana	30.92	7.00e-93	335.00
IUUC-Afu-008757	Aspergillus fumigatus	20.85	4.00e-29	123.00
IUUC-Ang-009797	Aspergillus niger	20.29	8.00e-21	95.90
IUUC-Bta-013336	Bos taurus	77.53	0.00e+00	2162.00
IUUC-Cel-018592	Caenorhabditis elegans	28.61	1.00e-73	272.00
IUUC-Cja-019094	Callithrix jacchus	78.59	0.00e+00	2206.00
IUUC-Cfa-020529	Canis familiaris	79.56	0.00e+00	2266.00
IUUC-Cpo-021970	Cavia porcellus	85.25	0.00e+00	1619.00
IUUC-Csa-024161	Chlorocebus sabaeus	79.69	0.00e+00	2206.00
IUUC-Cho-024310	Choloepus hoffmanni	83.79	0.00e+00	1149.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.68	3.00e-24	107.00
IUUC-Dno-029933	Dasypus novemcinctus	75.32	0.00e+00	2078.00
IUUC-Dor-031147	Dipodomys ordii	76.30	0.00e+00	2058.00
IUUC-Dse-031501	Dothistroma septosporum	29.39	1.00e-22	102.00
IUUC-Eca-033675	Equus caballus	79.65	0.00e+00	2243.00
IUUC-Eeu-034798	Erinaceus europaeus	89.56	0.00e+00	908.00
IUUC-Fca-035826	Felis catus	80.52	0.00e+00	2333.00
IUUC-Fso-038440	Fusarium solani	23.05	1.00e-35	145.00
IUUC-Gma-043644	Glycine max	31.70	1.00e-102	367.00
IUUC-Ggo-045152	Gorilla gorilla	80.60	0.00e+00	2191.00
IUUC-Hsa-045891	Homo sapiens	80.47	0.00e+00	2212.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.46	0.00e+00	1528.00
IUUC-Lch-049669	Latimeria chalumnae	56.88	0.00e+00	996.00
IUUC-Loc-052488	Lepisosteus oculatus	60.10	0.00e+00	1011.00
IUUC-Laf-053992	Loxodonta africana	78.05	0.00e+00	2207.00
IUUC-Mcc-054994	Macaca mulatta	81.06	0.00e+00	2199.00
IUUC-Meu-056815	Macropus eugenii	77.61	0.00e+00	1392.00
IUUC-Mtr-058383	Medicago truncatula	29.81	2.00e-49	190.00
IUUC-Mmr-060693	Microcebus murinus	78.67	0.00e+00	2164.00
IUUC-Mdo-063007	Monodelphis domestica	62.34	0.00e+00	1717.00
IUUC-Mmu-064067	Mus musculus	74.02	0.00e+00	2069.00
IUUC-Mpu-066532	Mustela putorius furo	80.95	0.00e+00	2325.00
IUUC-Mlu-066982	Myotis lucifugus	76.98	0.00e+00	2103.00
IUUC-Nle-070042	Nomascus leucogenys	84.83	0.00e+00	1883.00
IUUC-Opr-070397	Ochotona princeps	82.51	0.00e+00	2350.00
IUUC-Oga-088577	Otolemur garnettii	79.95	0.00e+00	2265.00
IUUC-Oar-090117	Ovis aries	76.44	0.00e+00	2102.00
IUUC-Ptr-090553	Pan troglodytes	80.54	0.00e+00	2238.00
IUUC-Pan-092559	Papio anubis	71.81	0.00e+00	1032.00
IUUC-Psi-093710	Pelodiscus sinensis	66.01	0.00e+00	1400.00
IUUC-Pab-098510	Pongo abelii	79.62	0.00e+00	2128.00
IUUC-Pop-099155	Populus trichocarpa	31.91	3.00e-99	357.00
IUUC-Pca-100323	Procavia capensis	71.87	0.00e+00	1327.00
IUUC-Pva-102895	Pteropus vampyrus	80.34	0.00e+00	2279.00
IUUC-Rno-105598	Rattus norvegicus	74.74	0.00e+00	2100.00
IUUC-Sha-107013	Sarcophilus harrisii	64.47	0.00e+00	1735.00
IUUC-Smo-109134	Selaginella moellendorffii	37.34	2.00e-135	477.00
IUUC-Sar-113261	Sorex araneus	74.16	0.00e+00	2040.00
IUUC-Ssc-115317	Sus scrofa	81.18	0.00e+00	2249.00
IUUC-Tsy-118799	Tarsius syrichta	89.72	0.00e+00	847.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.35	0.00e+00	783.00
IUUC-Tvi-122281	Trichoderma virens	24.11	7.00e-32	132.00
IUUC-Tme-127128	Tuber melanosporum	23.11	4.00e-30	127.00
IUUC-Tbe-127555	Tupaia belangeri	93.42	0.00e+00	1014.00
IUUC-Ttr-128722	Tursiops truncatus	78.31	0.00e+00	2209.00
IUUC-Vda-129957	Verticillium dahliae	24.49	3.00e-32	134.00
IUUC-Vpa-130392	Vicugna pacos	67.19	2.00e-100	360.00
IUUC-Vvi-131035	Vitis vinifera	32.83	9.00e-106	378.00
IUUC-Xtr-131789	Xenopus tropicalis	60.25	0.00e+00	980.00
IUUC-Yli-134437	Yarrowia lipolytica	26.44	6.00e-17	83.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence