iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088577

Ensembl Protein ID

ENSOGAP00000010300.2

UniProt Accession

H0X4Y4; H0X4Y4_OTOGA

Genbank Protein ID

ENSOGAP00000010300

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03125269

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000011496.2	ENSOGAT00000011506.2	ENSOGAP00000010300.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-26	91.4	153	190
UBD/Beta-Prp	2.60e-52	177.8	495	762

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g + +++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNL-IHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 582
           67899***********999998.799999999****************99887899***************997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtl 175
           ++++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ r  
   Q: 583  TAIKFAGNRdIQMISCGADKSIYF---RSAQRASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRIYNTvsgKQKKCYRGS 668
           *******885789*******9976...444444444444332112222233446777788****************9888999999999 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW............... 249
           +g +++s  ++++d++g++l++   d+++ + d+ +gec+ ++ gh++ v+ ++f+ +  +l+++s D  ++iW               
   Q: 669  QG-DEGSLLKVQVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitscmkqhll 756
           99.***********************************************************************777766666666666 PP
   S: 250  dlrsgd 255
            ++++d
   Q: 757  EIDHRD 762
           444444 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAALGPGGFA RTDATEKLPS VMAGVPARRG QSSPPPAPPL CLRRRTRPPT APEDTMHHRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHIINTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TAGGGCCCGG AGGCTTTGCG CGGACCGATG CGACTGAGAA GCTGCCATCA 60
GTCATGGCGG GAGTTCCAGC GCGGAGGGGC CAGTCCTCCC CGCCCCCCGC CCCGCCACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	82.31	0.00e+00	2392.00
IUUC-Atr-003165	Amborella trichopoda	34.46	6.00e-125	442.00
IUUC-Aca-004935	Anolis carolinensis	70.70	0.00e+00	996.00
IUUC-Acl-008257	Aspergillus clavatus	22.59	3.00e-23	103.00
IUUC-Afu-008757	Aspergillus fumigatus	21.90	4.00e-27	117.00
IUUC-Ang-009797	Aspergillus niger	20.69	2.00e-21	97.80
IUUC-Bta-013336	Bos taurus	79.29	0.00e+00	2241.00
IUUC-Cel-018592	Caenorhabditis elegans	28.84	1.00e-72	269.00
IUUC-Cja-019094	Callithrix jacchus	80.26	0.00e+00	2302.00
IUUC-Cfa-020529	Canis familiaris	82.23	0.00e+00	2392.00
IUUC-Cpo-021970	Cavia porcellus	85.11	0.00e+00	1626.00
IUUC-Csa-024161	Chlorocebus sabaeus	80.95	0.00e+00	2285.00
IUUC-Cho-024310	Choloepus hoffmanni	83.62	0.00e+00	1141.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.37	6.00e-22	99.80
IUUC-Dno-029933	Dasypus novemcinctus	76.73	0.00e+00	2180.00
IUUC-Dor-031147	Dipodomys ordii	76.83	0.00e+00	2097.00
IUUC-Dse-031501	Dothistroma septosporum	26.34	5.00e-22	100.00
IUUC-Eca-033675	Equus caballus	80.50	0.00e+00	2288.00
IUUC-Fca-035826	Felis catus	81.59	0.00e+00	2445.00
IUUC-Gma-043644	Glycine max	31.59	1.00e-101	365.00
IUUC-Ggo-045152	Gorilla gorilla	82.64	0.00e+00	2282.00
IUUC-Hsa-045891	Homo sapiens	82.51	0.00e+00	2304.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	90.90	0.00e+00	1523.00
IUUC-Lch-049669	Latimeria chalumnae	58.00	0.00e+00	991.00
IUUC-Loc-052488	Lepisosteus oculatus	52.49	0.00e+00	1061.00
IUUC-Laf-053992	Loxodonta africana	78.74	0.00e+00	2261.00
IUUC-Mcc-054994	Macaca mulatta	82.51	0.00e+00	2273.00
IUUC-Meu-056815	Macropus eugenii	79.49	0.00e+00	1385.00
IUUC-Mtr-058383	Medicago truncatula	30.25	2.00e-50	193.00
IUUC-Mmr-060693	Microcebus murinus	81.58	0.00e+00	2292.00
IUUC-Mdo-063007	Monodelphis domestica	61.66	0.00e+00	1738.00
IUUC-Mmu-064067	Mus musculus	74.94	0.00e+00	2141.00
IUUC-Mpu-066532	Mustela putorius furo	82.60	0.00e+00	2426.00
IUUC-Mlu-066982	Myotis lucifugus	77.81	0.00e+00	2160.00
IUUC-Nle-070042	Nomascus leucogenys	83.98	0.00e+00	1910.00
IUUC-Opr-070397	Ochotona princeps	78.15	0.00e+00	2278.00
IUUC-Oan-073119	Ornithorhynchus anatinus	66.47	0.00e+00	870.00
IUUC-Ocu-074274	Oryctolagus cuniculus	79.95	0.00e+00	2224.00
IUUC-Oar-090117	Ovis aries	77.14	0.00e+00	2166.00
IUUC-Ptr-090553	Pan troglodytes	82.83	0.00e+00	2336.00
IUUC-Pan-092559	Papio anubis	74.14	0.00e+00	1118.00
IUUC-Psi-093710	Pelodiscus sinensis	64.89	0.00e+00	1397.00
IUUC-Pab-098510	Pongo abelii	81.73	0.00e+00	2217.00
IUUC-Pca-100323	Procavia capensis	69.95	0.00e+00	1300.00
IUUC-Pva-102895	Pteropus vampyrus	81.87	0.00e+00	2334.00
IUUC-Rno-105598	Rattus norvegicus	75.57	0.00e+00	2184.00
IUUC-Sha-107013	Sarcophilus harrisii	65.23	0.00e+00	1773.00
IUUC-Sar-113261	Sorex araneus	72.66	0.00e+00	2076.00
IUUC-Ssc-115317	Sus scrofa	80.24	0.00e+00	2236.00
IUUC-Tsy-118799	Tarsius syrichta	89.28	0.00e+00	846.00
IUUC-Tvi-122281	Trichoderma virens	23.63	2.00e-27	118.00
IUUC-Tme-127128	Tuber melanosporum	23.50	2.00e-29	124.00
IUUC-Tbe-127555	Tupaia belangeri	92.50	0.00e+00	998.00
IUUC-Ttr-128722	Tursiops truncatus	79.46	0.00e+00	2275.00
IUUC-Vpa-130392	Vicugna pacos	68.97	2.00e-105	376.00
IUUC-Xtr-131789	Xenopus tropicalis	59.25	0.00e+00	981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence