iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047476

Ensembl Protein ID

MLOC_15791.1

UniProt Accession

M0UYW2; M0UYW2_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_15791	MLOC_15791.1	MLOC_15791.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.50e-123	413.0	137	446
E3 adaptor/Cullin RING/DCX/DWD	1.20e-22	80.1	272	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltg.hs 96
           e+ ldap+l dd+ylnL+dW+s++vl++aLg ++ylw+a++g+ s+l+ + e++  +tsvsw ++g++la+G +++ ++++D+++++ +rtl+g h 
   Q: 137  ERTLDAPDLVDDYYLNLMDWGSRDVLSIALGDTMYLWDASSGSTSELMTVeEDNGPITSVSWAPDGQHLAIGLNSSDIQLWDTSSNRLLRTLKGvHE 233
           689**********************************************9667779************************************66489 PP
   S: 97   arvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.........Plkkfkehkaavka 184
           +rvg+L+Wn+++l++G  dg+i+ +dvr++++ ++t+q+h+qevCGlkw+ ++++LasGGnDn +++wdas  +          l++ ++h aavka
   Q: 234  SRVGSLAWNDNILTTGCMDGRIVNNDVRIRDHAVQTYQGHSQEVCGLKWSGSGQQLASGGNDNLLHIWDASMASsmpspgrnqWLHRLEDHMAAVKA 330
           9********************************************************************99877787755555578999******** PP
   S: 185  iawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgea 281
           +aw+P+q++lLa+GGG++Drcikfwnt tga+l+++dtgsqvcsllw k+++el+s+hGf++n++tlwkyps+ k+ael+gh++Rvl +a spdg +
   Q: 331  LAWCPFQSNLLATGGGASDRCIKFWNTHTGACLNSVDTGSQVCSLLWNKNERELLSSHGFTHNQLTLWKYPSMVKMAELSGHTSRVLFMAQSPDGCT 427
           ************************************************************************************************* PP
   S: 282  ivtaagDetlrfwklfdkk 300
           +++a++Detlrfw +f + 
   Q: 428  VASASADETLRFWDVFGTP 446
           ****************865 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH+ +v++l++  s+  l+sG++D+ +++WD
   Q: 272  GHSQEVCGLKWsgSGQQLASGGNDNLLHIWD 302
           8**********976699************** PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MDAGSRSISS GKNRAGAVQR PPLQEAGSRP YMPSLSTRNP SAKCYGDRFI PDRSAMDMDV 60
AHYLLTEGKK DKENAAASPS KEAYRRLLAE KLLNNRTRIL AFRNKPPEPE KVFAADTVSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAAAAGAAC ACTTCCCTTG CCTCTTCCCT GGCGACTAGC CGTTGCGAGC CTGCGGCCGC 60
CCGTCGTCGA TCCCTACAAA TACCGCTAGC AATCAAATCC CCAAATCTCA CAAGCCATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	94.46	0.00e+00	907.00
IUUC-Aml-001545	Ailuropoda melanoleuca	44.90	1.00e-105	375.00
IUUC-Atr-002792	Amborella trichopoda	64.97	2.00e-172	597.00
IUUC-Apl-003255	Anas platyrhynchos	46.94	7.00e-109	386.00
IUUC-Aca-004920	Anolis carolinensis	46.76	5.00e-102	363.00
IUUC-Ago-007784	Ashbya gossypii	45.00	4.00e-81	293.00
IUUC-Bgr-012059	Blumeria graminis	38.56	2.00e-93	335.00
IUUC-Bta-012625	Bos taurus	45.35	2.00e-106	378.00
IUUC-Bdi-014344	Brachypodium distachyon	92.78	0.00e+00	900.00
IUUC-Cja-019132	Callithrix jacchus	46.03	8.00e-109	385.00
IUUC-Cfa-020780	Canis familiaris	45.80	2.00e-107	381.00
IUUC-Cpo-022223	Cavia porcellus	45.58	5.00e-97	347.00
IUUC-Csa-023666	Chlorocebus sabaeus	45.80	7.00e-108	382.00
IUUC-Cin-025675	Ciona intestinalis	48.28	3.00e-110	390.00
IUUC-Csv-026019	Ciona savignyi	47.51	4.00e-102	363.00
IUUC-Cne-026872	Cryptococcus neoformans	44.80	4.00e-89	320.00
IUUC-Dre-028026	Danio rerio	42.86	3.00e-105	374.00
IUUC-Dor-030958	Dipodomys ordii	44.15	1.00e-101	362.00
IUUC-Dme-031905	Drosophila melanogaster	45.88	1.00e-111	395.00
IUUC-Eca-033522	Equus caballus	40.59	3.00e-90	324.00
IUUC-Eeu-035059	Erinaceus europaeus	42.36	5.00e-88	317.00
IUUC-Fca-036346	Felis catus	43.47	1.00e-93	335.00
IUUC-Gmo-039284	Gadus morhua	45.13	4.00e-104	370.00
IUUC-Gac-041431	Gasterosteus aculeatus	42.82	8.00e-96	342.00
IUUC-Ggo-045052	Gorilla gorilla	46.03	4.00e-108	383.00
IUUC-Hsa-046305	Homo sapiens	46.03	4.00e-108	383.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	45.12	2.00e-96	345.00
IUUC-Lpe-050954	Leersia perrieri	88.94	0.00e+00	817.00
IUUC-Lma-052998	Leptosphaeria maculans	45.29	7.00e-95	340.00
IUUC-Laf-053742	Loxodonta africana	45.12	5.00e-106	376.00
IUUC-Mcc-054948	Macaca mulatta	45.80	7.00e-108	382.00
IUUC-Mmr-061615	Microcebus murinus	45.80	2.00e-107	381.00
IUUC-Mdo-061982	Monodelphis domestica	42.36	9.00e-86	311.00
IUUC-Mmu-063864	Mus musculus	44.90	4.00e-101	360.00
IUUC-Mpu-066502	Mustela putorius furo	47.06	1.00e-108	385.00
IUUC-Mlu-067277	Myotis lucifugus	46.59	8.00e-104	369.00
IUUC-Nle-070149	Nomascus leucogenys	45.58	5.00e-106	376.00
IUUC-Ont-071660	Oreochromis niloticus	44.39	1.00e-96	345.00
IUUC-Oba-075514	Oryza barthii	89.79	0.00e+00	837.00
IUUC-Ogl-077254	Oryza glaberrima	89.79	0.00e+00	838.00
IUUC-Ogu-078562	Oryza glumaepatula	89.57	0.00e+00	837.00
IUUC-Oin-080094	Oryza indica	89.79	0.00e+00	838.00
IUUC-Olo-080449	Oryza longistaminata	89.79	0.00e+00	850.00
IUUC-Oni-082243	Oryza nivara	89.79	0.00e+00	838.00
IUUC-Opu-084007	Oryza punctata	89.15	0.00e+00	832.00
IUUC-Oru-084357	Oryza rufipogon	89.57	0.00e+00	835.00
IUUC-Osa-086094	Oryza sativa	89.57	0.00e+00	836.00
IUUC-Ola-086907	Oryzias latipes	45.79	2.00e-96	344.00
IUUC-Oga-088184	Otolemur garnettii	44.80	4.00e-104	370.00
IUUC-Oar-090023	Ovis aries	46.94	3.00e-103	367.00
IUUC-Ptr-090935	Pan troglodytes	45.58	9.00e-107	379.00
IUUC-Pan-091845	Papio anubis	45.80	7.00e-108	382.00
IUUC-Psi-093188	Pelodiscus sinensis	46.21	5.00e-110	390.00
IUUC-Pma-094187	Petromyzon marinus	45.76	2.00e-98	351.00
IUUC-Pno-094809	Phaeosphaeria nodorum	46.06	7.00e-95	340.00
IUUC-Pab-098603	Pongo abelii	45.80	6.00e-108	383.00
IUUC-Pva-102925	Pteropus vampyrus	46.03	6.00e-108	383.00
IUUC-Pte-104142	Pyrenophora teres	45.62	6.00e-96	343.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	45.62	6.00e-96	343.00
IUUC-Rno-106005	Rattus norvegicus	44.67	2.00e-101	361.00
IUUC-Sce-106240	Saccharomyces cerevisiae	42.73	3.00e-82	297.00
IUUC-Sha-107472	Sarcophilus harrisii	45.23	5.00e-103	366.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	41.78	2.00e-91	328.00
IUUC-Sit-110732	Setaria italica	88.30	0.00e+00	857.00
IUUC-Stu-112024	Solanum tuberosum	73.09	0.00e+00	683.00
IUUC-Sar-113092	Sorex araneus	42.69	3.00e-94	337.00
IUUC-Ssc-115710	Sus scrofa	45.35	8.00e-107	379.00
IUUC-Tgu-117100	Taeniopygia guttata	46.70	2.00e-107	381.00
IUUC-Tru-118184	Takifugu rubripes	41.84	2.00e-90	324.00
IUUC-Tni-120474	Tetraodon nigroviridis	45.01	1.00e-96	345.00
IUUC-Tae-122784	Triticum aestivum	95.74	0.00e+00	928.00
IUUC-Tur-126193	Triticum urartu	95.44	0.00e+00	905.00
IUUC-Tbe-127384	Tupaia belangeri	49.66	9.00e-87	312.00
IUUC-Xtr-131993	Xenopus tropicalis	48.54	4.00e-110	390.00
IUUC-Xma-133332	Xiphophorus maculatus	45.56	2.00e-100	358.00
IUUC-Zma-135456	Zea mays	86.84	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence