iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107472

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01152803

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001965.1	ENSSHAT00000002233.1	ENSSHAP00000002209.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-27	93.5	307	336
E3 adaptor/Cullin RING/APC_C/CDC20	3.70e-145	483.1	172	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWsPDgRYLASGGNDNLVNVW 336
           8***********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWs  nvlavaL++svylwsa +g++ +l ++ +++d+v+sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLMDWSCGNVLAVALDTSVYLWSAGSGEILQLLQTeRPGDYVSSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689***********************************************9889*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++++hsarvgaL+Wn+++lssGsr+g+++h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++ s+    Pl+
   Q: 261  LRNMSSHSARVGALAWNSYILSSGSRSGHVHHHDVRVAEHHVATLSGHSQEVCGLRWSPDGRYLASGGNDNLVNVWPSAPSDggwgPLQ 349
           *******************************************************************************99999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h +avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvc +lws+++kel+s+hGfa+n++++wkyps++kvae
   Q: 350  TFTQHVGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAQSQVCAILWSPHYKELISGHGFAQNQLVIWKYPSMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           lkgh+aRvlsl++spdg ++++aa+Detlr+w++f+ ++a+
   Q: 439  LKGHTARVLSLTMSPDGCTVASAAADETLRLWRCFELDPAQ 479
           ************************************98876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAQFVFENDL HSLLQLDTSI VNAPPARWQR KARETPGPPP SPMRTANRSH SSGRTPGRTP 60
GKSGSKTQST PSKAGGDRYI PHRSTSQMEV ASFLLSKENQ PSNHTPTRKE QQKAWSLNLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTGTGTTTGA GAATGACCTG CACTCCCTGC TCCAGCTGGA CACATCTATT 60
GTCAACGCAC CTCCTGCTCG ATGGCAACGC AAAGCCAGGG AGACCCCCGG GCCCCCCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	45.64	1.00e-109	389.00
IUUC-Aml-001545	Ailuropoda melanoleuca	90.00	0.00e+00	876.00
IUUC-Atr-003103	Amborella trichopoda	44.34	7.00e-105	374.00
IUUC-Apl-003255	Anas platyrhynchos	80.00	0.00e+00	746.00
IUUC-Aca-004920	Anolis carolinensis	73.67	0.00e+00	748.00
IUUC-Aly-006303	Arabidopsis lyrata	47.93	1.00e-106	380.00
IUUC-Ath-006795	Arabidopsis thaliana	46.03	2.00e-106	379.00
IUUC-Ate-010479	Aspergillus terreus	49.85	6.00e-91	328.00
IUUC-Ame-010850	Astyanax mexicanus	60.49	4.00e-89	320.00
IUUC-Bgr-012059	Blumeria graminis	49.19	9.00e-94	337.00
IUUC-Bta-012625	Bos taurus	90.00	0.00e+00	876.00
IUUC-Bci-013607	Botrytis cinerea	48.34	1.00e-96	347.00
IUUC-Bdi-014063	Brachypodium distachyon	48.43	5.00e-109	387.00
IUUC-Bol-015368	Brassica oleracea	46.46	6.00e-106	379.00
IUUC-Bra-016738	Brassica rapa	46.75	9.00e-106	377.00
IUUC-Cja-019132	Callithrix jacchus	89.80	0.00e+00	875.00
IUUC-Cfa-020780	Canis familiaris	90.00	0.00e+00	875.00
IUUC-Cpo-022223	Cavia porcellus	89.60	0.00e+00	828.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.23	2.00e-115	409.00
IUUC-Csa-023666	Chlorocebus sabaeus	89.80	0.00e+00	874.00
IUUC-Cho-024920	Choloepus hoffmanni	87.63	2.00e-144	505.00
IUUC-Cin-025675	Ciona intestinalis	49.70	1.00e-128	453.00
IUUC-Csv-026019	Ciona savignyi	50.47	1.00e-123	436.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	41.04	3.00e-97	348.00
IUUC-Cme-027234	Cyanidioschyzon merolae	53.01	2.00e-107	382.00
IUUC-Dre-028026	Danio rerio	59.64	2.00e-179	622.00
IUUC-Dno-028865	Dasypus novemcinctus	87.62	0.00e+00	863.00
IUUC-Dor-030958	Dipodomys ordii	89.20	0.00e+00	874.00
IUUC-Dse-031391	Dothistroma septosporum	48.43	5.00e-96	345.00
IUUC-Dme-031905	Drosophila melanogaster	48.51	9.00e-139	486.00
IUUC-Ete-032387	Echinops telfairi	84.40	0.00e+00	832.00
IUUC-Eca-033522	Equus caballus	80.67	0.00e+00	775.00
IUUC-Eeu-035059	Erinaceus europaeus	79.24	0.00e+00	736.00
IUUC-Fca-036346	Felis catus	89.59	0.00e+00	795.00
IUUC-Fal-037558	Ficedula albicollis	79.17	0.00e+00	775.00
IUUC-Fox-037850	Fusarium oxysporum	47.66	2.00e-95	343.00
IUUC-Fso-038375	Fusarium solani	42.00	7.00e-97	347.00
IUUC-Gmo-039284	Gadus morhua	61.31	2.00e-179	622.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.12	2.00e-97	349.00
IUUC-Gga-040790	Gallus gallus	78.35	0.00e+00	799.00
IUUC-Gac-041431	Gasterosteus aculeatus	60.91	2.00e-177	615.00
IUUC-Gma-043489	Glycine max	47.23	6.00e-107	380.00
IUUC-Ggo-045052	Gorilla gorilla	89.60	0.00e+00	874.00
IUUC-Hsa-046305	Homo sapiens	89.60	0.00e+00	874.00
IUUC-Hvu-047476	Hordeum vulgare	45.23	2.00e-108	385.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	89.40	0.00e+00	827.00
IUUC-Lch-050174	Latimeria chalumnae	60.81	5.00e-171	593.00
IUUC-Lpe-050954	Leersia perrieri	47.55	2.00e-100	359.00
IUUC-Loc-052638	Lepisosteus oculatus	62.99	3.00e-179	620.00
IUUC-Lma-052998	Leptosphaeria maculans	42.07	4.00e-98	352.00
IUUC-Laf-053742	Loxodonta africana	89.80	0.00e+00	872.00
IUUC-Mcc-054948	Macaca mulatta	89.80	0.00e+00	874.00
IUUC-Meu-056013	Macropus eugenii	97.87	3.00e-163	568.00
IUUC-Mor-057277	Magnaporthe oryzae	41.74	8.00e-95	340.00
IUUC-Mpo-057624	Magnaporthe poae	50.81	7.00e-95	341.00
IUUC-Mtr-057725	Medicago truncatula	46.41	2.00e-98	352.00
IUUC-Mga-060102	Meleagris gallopavo	78.37	0.00e+00	798.00
IUUC-Mmr-061615	Microcebus murinus	89.40	0.00e+00	866.00
IUUC-Mdo-061982	Monodelphis domestica	97.05	0.00e+00	847.00
IUUC-Mmu-063864	Mus musculus	87.80	0.00e+00	866.00
IUUC-Mac-064861	Musa acuminata	47.22	2.00e-107	382.00
IUUC-Mpu-066502	Mustela putorius furo	90.00	0.00e+00	870.00
IUUC-Mlu-067277	Myotis lucifugus	83.83	0.00e+00	828.00
IUUC-Ncr-068951	Neurospora crassa	46.37	5.00e-94	338.00
IUUC-Nle-070149	Nomascus leucogenys	89.60	0.00e+00	868.00
IUUC-Opr-070778	Ochotona princeps	88.06	0.00e+00	629.00
IUUC-Ont-071660	Oreochromis niloticus	60.52	3.00e-175	607.00
IUUC-Oan-073677	Ornithorhynchus anatinus	74.55	0.00e+00	681.00
IUUC-Ocu-073797	Oryctolagus cuniculus	90.16	0.00e+00	874.00
IUUC-Oba-075514	Oryza barthii	47.45	5.00e-100	357.00
IUUC-Obr-076018	Oryza brachyantha	47.09	1.00e-106	379.00
IUUC-Ogl-077254	Oryza glaberrima	47.45	2.00e-100	359.00
IUUC-Ogu-078562	Oryza glumaepatula	47.20	6.00e-100	357.00
IUUC-Oin-080094	Oryza indica	47.45	2.00e-100	359.00
IUUC-Olo-080449	Oryza longistaminata	47.45	2.00e-100	359.00
IUUC-Ome-081186	Oryza meridionalis	47.33	2.00e-106	380.00
IUUC-Oni-082243	Oryza nivara	47.45	2.00e-100	359.00
IUUC-Opu-084007	Oryza punctata	47.45	3.00e-100	358.00
IUUC-Oru-084357	Oryza rufipogon	47.45	4.00e-100	358.00
IUUC-Osa-086094	Oryza sativa	47.45	3.00e-100	358.00
IUUC-Ola-086907	Oryzias latipes	60.28	8.00e-163	566.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.97	3.00e-117	415.00
IUUC-Oga-088184	Otolemur garnettii	88.22	0.00e+00	857.00
IUUC-Oar-090023	Ovis aries	85.38	0.00e+00	786.00
IUUC-Ptr-090935	Pan troglodytes	89.24	0.00e+00	816.00
IUUC-Pan-091845	Papio anubis	89.80	0.00e+00	874.00
IUUC-Psi-093188	Pelodiscus sinensis	78.79	0.00e+00	822.00
IUUC-Pma-094187	Petromyzon marinus	51.52	2.00e-141	495.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.44	4.00e-100	358.00
IUUC-Ppa-095457	Physcomitrella patens	50.00	1.00e-108	386.00
IUUC-Pfo-097429	Poecilia formosa	57.26	5.00e-156	543.00
IUUC-Pab-098603	Pongo abelii	89.80	0.00e+00	874.00
IUUC-Pop-099651	Populus trichocarpa	45.56	2.00e-102	365.00
IUUC-Pca-101062	Procavia capensis	88.80	0.00e+00	850.00
IUUC-Ppe-101865	Prunus persica	46.76	3.00e-96	345.00
IUUC-Pva-102925	Pteropus vampyrus	88.40	0.00e+00	890.00
IUUC-Pte-104142	Pyrenophora teres	42.24	4.00e-99	355.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	49.14	1.00e-98	353.00
IUUC-Rno-106005	Rattus norvegicus	87.60	0.00e+00	860.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.29	1.00e-93	337.00
IUUC-Spo-108075	Schizosaccharomyces pombe	45.21	8.00e-97	347.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	48.54	4.00e-96	345.00
IUUC-Smo-108922	Selaginella moellendorffii	49.03	1.00e-121	429.00
IUUC-Sit-110732	Setaria italica	46.68	2.00e-109	389.00
IUUC-Sly-111202	Solanum lycopersicum	44.87	8.00e-106	377.00
IUUC-Stu-112024	Solanum tuberosum	43.87	5.00e-107	381.00
IUUC-Sar-113092	Sorex araneus	85.00	0.00e+00	815.00
IUUC-Sbi-114558	Sorghum bicolor	47.49	6.00e-109	387.00
IUUC-Ssc-115710	Sus scrofa	90.60	0.00e+00	878.00
IUUC-Tgu-117100	Taeniopygia guttata	78.37	0.00e+00	776.00
IUUC-Tru-118184	Takifugu rubripes	59.86	1.00e-138	485.00
IUUC-Tsy-118892	Tarsius syrichta	87.99	1.00e-146	511.00
IUUC-Tni-120474	Tetraodon nigroviridis	58.93	3.00e-164	571.00
IUUC-Tca-120949	Theobroma cacao	46.30	2.00e-105	375.00
IUUC-Tre-122211	Trichoderma reesei	40.72	3.00e-97	348.00
IUUC-Tvi-122531	Trichoderma virens	40.44	4.00e-96	345.00
IUUC-Tae-123017	Triticum aestivum	45.11	2.00e-109	389.00
IUUC-Tur-126193	Triticum urartu	45.11	5.00e-109	388.00
IUUC-Tbe-127384	Tupaia belangeri	91.95	6.00e-165	573.00
IUUC-Ttr-128511	Tursiops truncatus	89.80	0.00e+00	871.00
IUUC-Vda-129993	Verticillium dahliae	39.53	9.00e-95	340.00
IUUC-Vvi-131245	Vitis vinifera	46.91	1.00e-95	343.00
IUUC-Xtr-131993	Xenopus tropicalis	72.90	0.00e+00	737.00
IUUC-Xma-133332	Xiphophorus maculatus	61.02	6.00e-173	600.00
IUUC-Zma-135135	Zea mays	47.94	3.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence