iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118026

UUCD1 version

UUC-TaR-00452

Ensembl Protein ID

ENSTRUP00000022321.1

UniProt Accession

H2TCC9; H2TCC9_TAKRU

Protein Name

Uncharacterized protein

Gene Name

hace1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008879.1	ENSTRUT00000022413.1	ENSTRUP00000022321.1
ENSTRUG00000008879.1	ENSTRUT00000022414.1	ENSTRUP00000022322.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-115	386.6	593	922

Active Site

Position(s)	Description	Evidence
893	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G++lg+al++++l+++ 
   Q: 593  EKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIINPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFRFAGQILGLALYHRQLVNIY 678
           78999**************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG +i Vt++Nk eYv+lv+e+
   Q: 679  FTRSFYKHILGIPVNYQDVSSIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGTSILVTQDNKAEYVQLVTEL 764
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf++ ip +l++lF+e elell++G++eidved+ ++t+y++g+ +++p++qwFwev++++++ee+  +LqFvT
   Q: 765  RMTRAIQPQINAFLQGFHTFIPASLIQLFDEYELELLLSGMPEIDVEDWCRNTEYTSGFGPQEPVVQWFWEVVKSLTQEECVLLLQFVT 853
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa+l+     ++f++       + lP+s+TC+n+LkLPeY+s e+lk++Ll+A + +  g
   Q: 854  GSSRVPHGGFAYLMggsgLQKFTVAAVPYIaNLLPTSSTCINMLKLPEYPSLEVLKDRLLVALHCGsYG 922
           ******************888999985555499******************************986555 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MERAMEQLNV QLSRLTRSLR RARTIELPED NETAVYTLMP MVMADQHRSV SELLLNSKFD 60
VNYAFGRVKR SLLHIAANCG SVECLVLLLK RGANPNYQDI SGCTPLHLAA RNGQKKCMGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAACGAG CGATGGAGCA GCTCAACGTG CAGCTCAGCC GCCTGACCCG CTCCCTCCGC 60
CGGGCCAGGA CCATAGAACT CCCGGAAGGT GACGCCGCCG CCGCGGGGCA AACAGTTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT

Pfam

PF12796--Ank_2
PF00632--HECT

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001490	Ailuropoda melanoleuca	82.22	0.00e+00	1583.00
IUUC-Apl-003400	Anas platyrhynchos	77.52	0.00e+00	1022.00
IUUC-Aca-005375	Anolis carolinensis	81.76	0.00e+00	1585.00
IUUC-Ame-011847	Astyanax mexicanus	88.89	0.00e+00	1704.00
IUUC-Bta-012831	Bos taurus	81.69	0.00e+00	1552.00
IUUC-Cja-019160	Callithrix jacchus	82.63	0.00e+00	1592.00
IUUC-Cfa-020346	Canis familiaris	82.38	0.00e+00	1592.00
IUUC-Cpo-021766	Cavia porcellus	81.95	0.00e+00	1586.00
IUUC-Csa-023768	Chlorocebus sabaeus	82.14	0.00e+00	1594.00
IUUC-Cho-024688	Choloepus hoffmanni	75.28	0.00e+00	957.00
IUUC-Cin-025417	Ciona intestinalis	49.68	1.00e-135	477.00
IUUC-Csv-025993	Ciona savignyi	45.99	5.00e-140	491.00
IUUC-Dre-027819	Danio rerio	87.81	0.00e+00	1676.00
IUUC-Dno-029027	Dasypus novemcinctus	81.54	0.00e+00	1574.00
IUUC-Dor-030327	Dipodomys ordii	75.27	0.00e+00	1380.00
IUUC-Ete-032966	Echinops telfairi	76.03	0.00e+00	1452.00
IUUC-Eca-034339	Equus caballus	82.38	0.00e+00	1590.00
IUUC-Eeu-034544	Erinaceus europaeus	73.82	4.00e-134	472.00
IUUC-Fca-035617	Felis catus	78.73	0.00e+00	1085.00
IUUC-Fal-036687	Ficedula albicollis	81.80	0.00e+00	1604.00
IUUC-Gmo-039508	Gadus morhua	80.00	0.00e+00	1190.00
IUUC-Gga-040845	Gallus gallus	81.80	0.00e+00	1609.00
IUUC-Gac-041894	Gasterosteus aculeatus	89.87	0.00e+00	1666.00
IUUC-Ggo-044465	Gorilla gorilla	79.05	0.00e+00	1520.00
IUUC-Hsa-045731	Homo sapiens	82.50	0.00e+00	1597.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	82.29	0.00e+00	1595.00
IUUC-Lch-050436	Latimeria chalumnae	84.11	0.00e+00	1624.00
IUUC-Loc-052287	Lepisosteus oculatus	86.60	0.00e+00	1697.00
IUUC-Laf-053846	Loxodonta africana	82.50	0.00e+00	1597.00
IUUC-Mcc-055845	Macaca mulatta	82.24	0.00e+00	1597.00
IUUC-Meu-056060	Macropus eugenii	83.80	2.00e-178	619.00
IUUC-Mga-059935	Meleagris gallopavo	82.01	0.00e+00	1580.00
IUUC-Mmr-060960	Microcebus murinus	82.14	0.00e+00	1596.00
IUUC-Mdo-061851	Monodelphis domestica	81.94	0.00e+00	1597.00
IUUC-Mmu-063657	Mus musculus	82.27	0.00e+00	1592.00
IUUC-Mpu-066161	Mustela putorius furo	89.70	0.00e+00	754.00
IUUC-Mlu-067354	Myotis lucifugus	81.18	0.00e+00	1516.00
IUUC-Nle-069112	Nomascus leucogenys	82.50	0.00e+00	1597.00
IUUC-Opr-070686	Ochotona princeps	79.95	0.00e+00	734.00
IUUC-Ont-072398	Oreochromis niloticus	90.17	0.00e+00	1694.00
IUUC-Oan-073194	Ornithorhynchus anatinus	82.08	0.00e+00	1535.00
IUUC-Ocu-074397	Oryctolagus cuniculus	75.59	0.00e+00	1400.00
IUUC-Ola-086777	Oryzias latipes	87.11	0.00e+00	1640.00
IUUC-Oga-088684	Otolemur garnettii	82.40	0.00e+00	1589.00
IUUC-Oar-089428	Ovis aries	81.51	0.00e+00	1553.00
IUUC-Ptr-090529	Pan troglodytes	82.40	0.00e+00	1595.00
IUUC-Pan-091702	Papio anubis	82.24	0.00e+00	1596.00
IUUC-Psi-093969	Pelodiscus sinensis	81.26	0.00e+00	1541.00
IUUC-Pfo-097364	Poecilia formosa	89.42	0.00e+00	1673.00
IUUC-Pab-098574	Pongo abelii	82.50	0.00e+00	1597.00
IUUC-Pca-100525	Procavia capensis	77.07	6.00e-160	558.00
IUUC-Pva-102365	Pteropus vampyrus	72.32	0.00e+00	1341.00
IUUC-Rno-105153	Rattus norvegicus	82.17	0.00e+00	1593.00
IUUC-Sha-107319	Sarcophilus harrisii	82.24	0.00e+00	1600.00
IUUC-Stu-112894	Solanum tuberosum	33.90	3.00e-53	203.00
IUUC-Sar-113449	Sorex araneus	59.95	4.00e-128	452.00
IUUC-Ssc-115865	Sus scrofa	82.06	0.00e+00	1584.00
IUUC-Tgu-117225	Taeniopygia guttata	81.69	0.00e+00	1607.00
IUUC-Tsy-119407	Tarsius syrichta	70.40	0.00e+00	1308.00
IUUC-Tni-120234	Tetraodon nigroviridis	93.64	0.00e+00	1401.00
IUUC-Tbe-127708	Tupaia belangeri	67.76	0.00e+00	686.00
IUUC-Ttr-128667	Tursiops truncatus	81.95	0.00e+00	1586.00
IUUC-Vpa-130200	Vicugna pacos	82.02	0.00e+00	1534.00
IUUC-Xtr-132176	Xenopus tropicalis	82.57	0.00e+00	1613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence