iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010112.1	ENSSHAT00000011873.1	ENSSHAP00000011777.1
ENSSHAG00000010112.1	ENSSHAT00000011874.1	ENSSHAP00000011778.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-41	138.8	1513	1545
UBD/Beta-Prp	6.00e-94	314.7	1390	1686

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH+++v+ + f ++  + ++++dDg+++vW+l 
   Q: 1513 GHKNKVNEVTFsPTeSHCATCGDDGSVRVWSLA 1545
           8***********7779***************86 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           +                                          +l +g + + i+vwd+st+ c++t+++ e ++  l  s   ++l
   Q: 1390 P------------------------------------------LLYSGTNTGQICVWDISTNRCFMTWEADEGEIGVLLCSG--NRL 1432
           3..........................................455555555555555555555555555555555554444..555 PP
   S: 110  vsGshdrtirvwdletgqclee.......................................................tlsghdgvvn 141
           vsGs+ + ir+w +   q+l+                                                        + sgh+  vn
   Q: 1433 VSGSNTKRIRLWAVGAVQELRLkgsgarsssvfmeqemtldgavisasfddsmdmgivgttagtlwyinwaertnirLISGHKNKVN 1519
           5555555555555555555554555555555555555555555555555555555555555555555555555555599******** PP
   S: 142  cvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.......kelvsgsldgtvklwdlqtgecvrtlngh 221
            v+++p+++ ++++++D+ vr+W+l++++l+ +++   ++s  +l+++++        +++v+g  dgt+++++++++e+  + + h
   Q: 1520 EVTFSPTESHCATCGDDGSVRVWSLASMELVVQFQV-LNQSCLCLAWSPSAhssrsdhQQVVAGYSDGTIRVFSISRTEMELKIHPH 1605
           **********************************98.*********888778888888***************************** PP
   S: 222  tdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav........lsfgdnvlvlgsedskvniwkl 294
               + + fs ++++++sg +Dg + +   r+g ++++l  h+ s i v          +++++   +++s+d +v +w+ 
   Q: 1606 PVALTAISFSVDGQIIISGDKDGIVAVSSPRTGITIRVLDDHKGSPITVIQsksreyydFGLEGELWLAASADRRVSVWAS 1686
           *******************************************55444444477887566666888899999*******85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MARVWQHPFL NVFKHLKVEE WKRSTKEGDV TTVMDKTLKG TVYRIRGAIP AGNFIQLPKT 60
STQSLGLTGR YLYLLFRPIP MKYFVVHLDV TTEDSQVIRI SFSNLFKEFK STSTWLQFPF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGAG GTAGTGGAGC GGGCGCTGGG TGGGGCGGCG GNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

KEGG

shr:100930162

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	58.18	0.00e+00	2108.00
IUUC-Apl-003387	Anas platyrhynchos	61.68	0.00e+00	2081.00
IUUC-Aca-005235	Anolis carolinensis	63.18	0.00e+00	2036.00
IUUC-Ame-011595	Astyanax mexicanus	51.92	0.00e+00	1888.00
IUUC-Bta-012328	Bos taurus	57.06	0.00e+00	2031.00
IUUC-Cja-019058	Callithrix jacchus	55.89	0.00e+00	1028.00
IUUC-Cfa-020934	Canis familiaris	55.63	0.00e+00	1954.00
IUUC-Cpo-022025	Cavia porcellus	57.24	0.00e+00	2033.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	30.66	2.00e-72	268.00
IUUC-Csa-023022	Chlorocebus sabaeus	57.15	0.00e+00	2071.00
IUUC-Cin-025133	Ciona intestinalis	41.29	0.00e+00	831.00
IUUC-Csv-025816	Ciona savignyi	36.68	0.00e+00	1150.00
IUUC-Dre-028823	Danio rerio	50.77	0.00e+00	1814.00
IUUC-Dno-029211	Dasypus novemcinctus	66.88	0.00e+00	886.00
IUUC-Dor-030211	Dipodomys ordii	57.17	0.00e+00	1816.00
IUUC-Ete-032363	Echinops telfairi	50.34	0.00e+00	820.00
IUUC-Eca-034296	Equus caballus	58.95	0.00e+00	2045.00
IUUC-Eeu-035226	Erinaceus europaeus	47.60	0.00e+00	752.00
IUUC-Fca-035384	Felis catus	57.74	0.00e+00	2100.00
IUUC-Fal-037660	Ficedula albicollis	60.85	0.00e+00	2085.00
IUUC-Gga-040666	Gallus gallus	65.45	0.00e+00	1586.00
IUUC-Gac-041358	Gasterosteus aculeatus	50.62	0.00e+00	1762.00
IUUC-Ggo-045121	Gorilla gorilla	57.14	0.00e+00	2080.00
IUUC-Hsa-046289	Homo sapiens	57.32	0.00e+00	2040.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	60.53	0.00e+00	1681.00
IUUC-Lch-050009	Latimeria chalumnae	57.69	0.00e+00	2029.00
IUUC-Loc-052629	Lepisosteus oculatus	54.40	0.00e+00	1047.00
IUUC-Mcc-055834	Macaca mulatta	52.84	0.00e+00	1817.00
IUUC-Meu-056162	Macropus eugenii	81.96	0.00e+00	1088.00
IUUC-Mga-060167	Meleagris gallopavo	60.57	0.00e+00	1972.00
IUUC-Mmr-060761	Microcebus murinus	67.32	6.00e-125	439.00
IUUC-Mdo-061886	Monodelphis domestica	87.27	0.00e+00	3272.00
IUUC-Mmu-063652	Mus musculus	61.09	0.00e+00	1815.00
IUUC-Mlu-068141	Myotis lucifugus	59.53	0.00e+00	2127.00
IUUC-Nle-069133	Nomascus leucogenys	52.27	0.00e+00	1679.00
IUUC-Ont-072496	Oreochromis niloticus	53.82	0.00e+00	1974.00
IUUC-Oan-072833	Ornithorhynchus anatinus	54.03	0.00e+00	1056.00
IUUC-Ola-086564	Oryzias latipes	49.67	0.00e+00	1767.00
IUUC-Oga-088919	Otolemur garnettii	58.69	0.00e+00	1753.00
IUUC-Oar-089946	Ovis aries	66.72	0.00e+00	888.00
IUUC-Ptr-090755	Pan troglodytes	59.77	0.00e+00	1737.00
IUUC-Pan-092054	Papio anubis	56.84	0.00e+00	2061.00
IUUC-Psi-093467	Pelodiscus sinensis	69.34	0.00e+00	2505.00
IUUC-Pma-094573	Petromyzon marinus	42.95	0.00e+00	1525.00
IUUC-Ppa-095984	Physcomitrella patens	21.59	1.00e-15	78.20
IUUC-Pfo-096849	Poecilia formosa	49.15	0.00e+00	1674.00
IUUC-Pab-098320	Pongo abelii	56.15	0.00e+00	1819.00
IUUC-Pca-100172	Procavia capensis	55.05	0.00e+00	1885.00
IUUC-Pva-102772	Pteropus vampyrus	57.90	0.00e+00	1171.00
IUUC-Rno-105046	Rattus norvegicus	58.16	0.00e+00	2151.00
IUUC-Smo-109208	Selaginella moellendorffii	23.23	8.00e-26	111.00
IUUC-Ssc-116257	Sus scrofa	55.74	0.00e+00	1955.00
IUUC-Tgu-117323	Taeniopygia guttata	58.55	0.00e+00	1707.00
IUUC-Tru-118717	Takifugu rubripes	49.15	0.00e+00	1722.00
IUUC-Tni-120108	Tetraodon nigroviridis	49.09	0.00e+00	1696.00
IUUC-Ttr-128378	Tursiops truncatus	68.05	0.00e+00	918.00
IUUC-Xtr-131760	Xenopus tropicalis	55.86	0.00e+00	2013.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence