iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066917

Ensembl Protein ID

ENSMPUP00000005210.1

UniProt Accession

M3Y1K9; M3Y1K9_MUSPF

Genbank Protein ID

ENSMPUP00000005210

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01010078

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005248.1	ENSMPUT00000005298.1	ENSMPUP00000005210.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-69	235.2	1894	2239

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1894 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1973
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1974 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2032
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2033 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2114
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2115 MTPYTEDflmgksdrkegfkevsDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2201
           **********99999999999986666777***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2202 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2239
           7779********************************96 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

LIPNIKKCFF YFISVSDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN 60
QVVCALINLV IAQVQVLRDQ LCKHCTAINI DSTWQDETNQ VEEPLNIERE CKEGSTERQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTATTCCTA ATATTAAAAA GTGTTTTTTC TACTTTATTT CAGTATCAGA TATAGAAGGT 60
GGTGATGGAC TGCAGCTCAG AAAGGAACAT ACTCTCAAAA TATTTGCTTA TATCAATTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR011030--Vitellinogen_superhlx

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	96.95	0.00e+00	6714.00
IUUC-Apl-003284	Anas platyrhynchos	92.69	0.00e+00	6125.00
IUUC-Aca-004415	Anolis carolinensis	90.82	0.00e+00	6264.00
IUUC-Acl-008140	Aspergillus clavatus	28.97	7.00e-64	240.00
IUUC-Afl-008381	Aspergillus flavus	28.16	7.00e-64	240.00
IUUC-Afu-008857	Aspergillus fumigatus	27.35	6.00e-64	240.00
IUUC-Ani-009257	Aspergillus nidulans	28.87	9.00e-57	216.00
IUUC-Ang-009759	Aspergillus niger	28.02	1.00e-63	239.00
IUUC-Aor-009931	Aspergillus oryzae	28.64	6.00e-64	240.00
IUUC-Ate-010246	Aspergillus terreus	29.03	9.00e-53	203.00
IUUC-Ame-011219	Astyanax mexicanus	61.46	0.00e+00	2274.00
IUUC-Bgr-012195	Blumeria graminis	26.62	8.00e-65	243.00
IUUC-Bta-012989	Bos taurus	96.36	0.00e+00	6641.00
IUUC-Bci-013798	Botrytis cinerea	32.44	3.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	96.93	0.00e+00	825.00
IUUC-Cfa-021214	Canis familiaris	97.14	0.00e+00	6727.00
IUUC-Cpo-021912	Cavia porcellus	98.22	0.00e+00	4770.00
IUUC-Csa-023658	Chlorocebus sabaeus	96.15	0.00e+00	6645.00
IUUC-Cho-024971	Choloepus hoffmanni	79.81	0.00e+00	3013.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	27.99	6.00e-64	240.00
IUUC-Dre-027428	Danio rerio	82.59	0.00e+00	4434.00
IUUC-Dno-029690	Dasypus novemcinctus	95.57	0.00e+00	6484.00
IUUC-Dor-030817	Dipodomys ordii	81.74	0.00e+00	1952.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	1.00e-35	146.00
IUUC-Dme-032102	Drosophila melanogaster	50.13	0.00e+00	754.00
IUUC-Ete-032552	Echinops telfairi	88.88	0.00e+00	2812.00
IUUC-Eca-033457	Equus caballus	96.55	0.00e+00	6391.00
IUUC-Eeu-035118	Erinaceus europaeus	89.16	0.00e+00	2882.00
IUUC-Fca-036213	Felis catus	93.67	0.00e+00	4897.00
IUUC-Fal-037643	Ficedula albicollis	90.26	0.00e+00	6223.00
IUUC-Fox-037971	Fusarium oxysporum	27.27	1.00e-63	239.00
IUUC-Fso-038108	Fusarium solani	27.10	2.00e-60	229.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.16	2.00e-62	236.00
IUUC-Gga-040511	Gallus gallus	90.17	0.00e+00	6259.00
IUUC-Gac-042024	Gasterosteus aculeatus	78.57	0.00e+00	4214.00
IUUC-Ggo-044924	Gorilla gorilla	93.06	0.00e+00	6180.00
IUUC-Hsa-046913	Homo sapiens	96.21	0.00e+00	6675.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	96.22	0.00e+00	6672.00
IUUC-Lch-049675	Latimeria chalumnae	84.07	0.00e+00	4752.00
IUUC-Loc-052832	Lepisosteus oculatus	84.55	0.00e+00	5737.00
IUUC-Lma-053130	Leptosphaeria maculans	27.66	2.00e-61	232.00
IUUC-Laf-054169	Loxodonta africana	94.80	0.00e+00	6615.00
IUUC-Mcc-055847	Macaca mulatta	95.30	0.00e+00	6554.00
IUUC-Meu-056327	Macropus eugenii	76.60	0.00e+00	1366.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	7.00e-62	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.28	2.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	96.44	0.00e+00	6689.00
IUUC-Mdo-062308	Monodelphis domestica	90.66	0.00e+00	6005.00
IUUC-Mmu-063457	Mus musculus	93.98	0.00e+00	6541.00
IUUC-Mlu-067696	Myotis lucifugus	96.38	0.00e+00	6656.00
IUUC-Nfi-068259	Neosartorya fischeri	27.70	2.00e-64	242.00
IUUC-Ncr-068911	Neurospora crassa	25.71	7.00e-60	227.00
IUUC-Nle-069586	Nomascus leucogenys	96.13	0.00e+00	6700.00
IUUC-Opr-070447	Ochotona princeps	88.53	0.00e+00	2689.00
IUUC-Ont-072396	Oreochromis niloticus	79.95	0.00e+00	5289.00
IUUC-Oan-073147	Ornithorhynchus anatinus	92.62	0.00e+00	6418.00
IUUC-Ocu-074324	Oryctolagus cuniculus	95.98	0.00e+00	6636.00
IUUC-Ola-086312	Oryzias latipes	80.01	0.00e+00	5088.00
IUUC-Oga-088878	Otolemur garnettii	96.33	0.00e+00	6688.00
IUUC-Oar-089919	Ovis aries	96.37	0.00e+00	6655.00
IUUC-Ptr-090713	Pan troglodytes	95.97	0.00e+00	6109.00
IUUC-Pan-091957	Papio anubis	95.73	0.00e+00	4936.00
IUUC-Psi-093240	Pelodiscus sinensis	92.06	0.00e+00	6364.00
IUUC-Pma-094469	Petromyzon marinus	71.22	0.00e+00	3906.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.39	5.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	77.61	0.00e+00	5324.00
IUUC-Pab-098003	Pongo abelii	95.57	0.00e+00	6319.00
IUUC-Pca-100799	Procavia capensis	88.83	0.00e+00	1899.00
IUUC-Pva-103226	Pteropus vampyrus	91.46	0.00e+00	6244.00
IUUC-Pte-104235	Pyrenophora teres	32.13	2.00e-58	222.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.33	6.00e-61	230.00
IUUC-Rno-105389	Rattus norvegicus	93.61	0.00e+00	5356.00
IUUC-Sha-106979	Sarcophilus harrisii	92.50	0.00e+00	6412.00
IUUC-Sar-113444	Sorex araneus	89.35	0.00e+00	5809.00
IUUC-Ssc-115815	Sus scrofa	96.01	0.00e+00	5551.00
IUUC-Tgu-117470	Taeniopygia guttata	91.94	0.00e+00	6054.00
IUUC-Tru-118543	Takifugu rubripes	80.13	0.00e+00	5178.00
IUUC-Tsy-119081	Tarsius syrichta	86.40	0.00e+00	4726.00
IUUC-Tni-120294	Tetraodon nigroviridis	81.90	6.00e-165	573.00
IUUC-Tre-122057	Trichoderma reesei	29.91	4.00e-63	238.00
IUUC-Tvi-122570	Trichoderma virens	35.89	2.00e-59	226.00
IUUC-Tme-127154	Tuber melanosporum	27.50	2.00e-59	224.00
IUUC-Tbe-127801	Tupaia belangeri	82.66	0.00e+00	3125.00
IUUC-Ttr-129262	Tursiops truncatus	92.19	0.00e+00	6309.00
IUUC-Vda-129686	Verticillium dahliae	27.91	4.00e-62	234.00
IUUC-Vpa-130484	Vicugna pacos	92.25	0.00e+00	6261.00
IUUC-Xtr-131769	Xenopus tropicalis	84.03	0.00e+00	5888.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence