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Tag Content
iUUCD ID IUUC-Oar-089736
Ensembl Protein ID ENSOARP00000016840.1
UniProt Accession W5Q2A2; W5Q2A2_SHEEP
Genbank Protein ID ENSOARP00000016840
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AMGL01100931
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000015690.1 ENSOART00000017079.1 ENSOARP00000016840.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.40e-16 59.8 794 834
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl++     +p+ + w+C++Cr
   Q: 794  WCFVCSKGGS----LLCCESCPAAFHPDCLSID----MPDGS-WFCNDCR 834
           8*********....*******************....9***8.******8 PP
   
Organism Ovis aries
Protein Sequence
(Fasta)
MEFSVRKSPL SAPKVAKCMK MKQAPEVLGS ANGKTPSCDV SRECSVFLSK AQLSAGLQDG 60
VVQKFNGHDA LPFIPAERLK DLTSRVFNGE PGAHDAKLRF ESQEVKGLGT PPHTTPVKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oar-089736|E3,PHD|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCCCCCCCC CCGGGGCCCC GGGGGCGCGC GCGATGGAGC GGCCGCGGCC GCCCGGCAGG 60
CTCTGCCCCG CTCGCCAGAG GGCAGTTTAA GAAAAATCTC GGCATTGGAG ACACGCGGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oar-089736|E3,PHD|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 80.79 0.00e+00 1996.00
IUUC-Apl-003677 Anas platyrhynchos 71.27 0.00e+00 1783.00
IUUC-Aca-004278 Anolis carolinensis 72.06 0.00e+00 1219.00
IUUC-Bta-012522 Bos taurus 87.69 0.00e+00 2088.00
IUUC-Cja-018908 Callithrix jacchus 80.08 0.00e+00 1968.00
IUUC-Cfa-020894 Canis familiaris 80.36 0.00e+00 2024.00
IUUC-Cpo-021982 Cavia porcellus 78.63 0.00e+00 1960.00
IUUC-Csa-023807 Chlorocebus sabaeus 80.97 0.00e+00 1990.00
IUUC-Cho-024405 Choloepus hoffmanni 60.64 6.00e-167 581.00
IUUC-Dre-027492 Danio rerio 72.94 0.00e+00 951.00
IUUC-Dno-030020 Dasypus novemcinctus 78.29 0.00e+00 1797.00
IUUC-Dor-031103 Dipodomys ordii 73.79 0.00e+00 1759.00
IUUC-Ete-032488 Echinops telfairi 73.57 0.00e+00 1827.00
IUUC-Eca-034066 Equus caballus 81.20 0.00e+00 2044.00
IUUC-Eeu-035199 Erinaceus europaeus 62.90 0.00e+00 650.00
IUUC-Fca-035434 Felis catus 77.87 0.00e+00 1617.00
IUUC-Fal-037113 Ficedula albicollis 70.66 0.00e+00 1801.00
IUUC-Gmo-039686 Gadus morhua 69.51 0.00e+00 910.00
IUUC-Gga-040273 Gallus gallus 70.15 0.00e+00 1776.00
IUUC-Gac-042123 Gasterosteus aculeatus 48.14 0.00e+00 1097.00
IUUC-Ggo-044643 Gorilla gorilla 80.83 0.00e+00 2003.00
IUUC-Hsa-046380 Homo sapiens 80.97 0.00e+00 1987.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 86.80 0.00e+00 1216.00
IUUC-Lch-050217 Latimeria chalumnae 62.02 0.00e+00 1525.00
IUUC-Lpe-051661 Leersia perrieri 29.21 5.00e-12 67.00
IUUC-Laf-053780 Loxodonta africana 79.12 0.00e+00 1991.00
IUUC-Mcc-054928 Macaca mulatta 80.97 0.00e+00 2009.00
IUUC-Meu-056184 Macropus eugenii 66.55 0.00e+00 699.00
IUUC-Mga-059576 Meleagris gallopavo 70.73 0.00e+00 1775.00
IUUC-Mmr-061045 Microcebus murinus 79.49 0.00e+00 1981.00
IUUC-Mdo-062576 Monodelphis domestica 73.81 0.00e+00 1847.00
IUUC-Mmu-063640 Mus musculus 79.11 0.00e+00 1961.00
IUUC-Mac-065303 Musa acuminata 29.22 6.00e-11 62.80
IUUC-Mpu-066512 Mustela putorius furo 80.82 0.00e+00 1983.00
IUUC-Mlu-067280 Myotis lucifugus 76.21 0.00e+00 925.00
IUUC-Nle-069896 Nomascus leucogenys 80.87 0.00e+00 2008.00
IUUC-Ont-072197 Oreochromis niloticus 73.31 0.00e+00 924.00
IUUC-Oan-072724 Ornithorhynchus anatinus 69.79 0.00e+00 1177.00
IUUC-Ocu-074758 Oryctolagus cuniculus 77.86 0.00e+00 1896.00
IUUC-Olo-080702 Oryza longistaminata 42.66 1.00e-44 174.00
IUUC-Opu-083371 Oryza punctata 41.88 2.00e-46 181.00
IUUC-Oga-088702 Otolemur garnettii 78.49 0.00e+00 1794.00
IUUC-Ptr-091055 Pan troglodytes 80.97 0.00e+00 1984.00
IUUC-Pan-092752 Papio anubis 88.46 0.00e+00 1217.00
IUUC-Psi-093620 Pelodiscus sinensis 72.34 0.00e+00 1808.00
IUUC-Pfo-097464 Poecilia formosa 49.96 0.00e+00 1096.00
IUUC-Pab-098051 Pongo abelii 80.89 0.00e+00 2001.00
IUUC-Pop-099927 Populus trichocarpa 30.46 1.00e-12 68.60
IUUC-Pca-100273 Procavia capensis 79.26 0.00e+00 1945.00
IUUC-Pva-102473 Pteropus vampyrus 74.94 0.00e+00 1792.00
IUUC-Rno-105056 Rattus norvegicus 79.26 0.00e+00 1961.00
IUUC-Sha-107494 Sarcophilus harrisii 74.71 0.00e+00 1836.00
IUUC-Sar-113310 Sorex araneus 80.02 0.00e+00 1624.00
IUUC-Ssc-116344 Sus scrofa 80.60 0.00e+00 1952.00
IUUC-Tgu-116786 Taeniopygia guttata 71.58 0.00e+00 1798.00
IUUC-Tru-117638 Takifugu rubripes 48.68 0.00e+00 1090.00
IUUC-Tsy-118937 Tarsius syrichta 86.28 0.00e+00 1282.00
IUUC-Tbe-127291 Tupaia belangeri 78.33 0.00e+00 1254.00
IUUC-Ttr-129017 Tursiops truncatus 76.11 0.00e+00 1574.00
IUUC-Xtr-132673 Xenopus tropicalis 62.49 0.00e+00 1547.00
Created Date 25-Jun-2017

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