iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098145

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01341272

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005008.1	ENSPPYT00000005928.1	ENSPPYP00000005710.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	7.00e-15	54.7	356	403
E3 adaptor/Cullin RING/DCX/DWD	4.10e-32	108.9	151	184
UBD/Beta-Prp	5.10e-46	157.3	125	360

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+a r++l+++++    +LP+Pk++k++L y++
   Q: 356  HVQFWTAPRVLSSLKHLCRKALRSFLTTYQV---LALPIPKKMKEFLTYRT 403
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           gH+d v++l+f  s+  +lvs+s+D+t+++WDl 
   Q: 151  GHQDVVRDLSFtpSGsLILVSASRDKTLRIWDLN 184
           8***********6556779*************85 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklv 110
           +latg  dg ik+w+v+tg ll  lsgh++ v++++f p+g+ ilv++s+D+t+++wdl+  gk++++l+gh + v+++s+sp+ + l 
   Q: 125  VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSlILVSASRDKTLRIWDLNkHGKQIQVLSGHLQWVYCCSISPDCSMLC 213
           79****************************************9****************9789********************99**** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...........tgghtdsvyslsf 188
           s+   + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D+ v +Wd  tg+ lr l           +  h +s +s+ f
   Q: 214  SAAGEKSVFLWSMRSYTLIR-KLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLhhtqvdpamddSDVHISSLRSVCF 301
           ********************.********************************************99999999888777888888888* PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++g +l+++++d+ +++w l+ ++   +  +  +n ++  f+p++  +++g+ Dg +++W
   Q: 302  SPEGLYLATVADDRLLRIWALELKT--PIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 360
           *********************9885..7899****************************** PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MEAGEEPLLL AELKPGRPHQ FDWKSSCETW SVAFSPDGSW FAWSQGHCIV KLIPWPLEEQ 60
FIPKGFEAKS RSGKNETKGR GSPKEKTLDC GQIVWGLAFS PWPSPPSRKL WARHHPQVPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCCG GAGGTGAGTG GGGCCGGGCG CGCCCGTTCC CGCCCGGCGG GGCCCTGGCC 60
CGTTCTCCCC GGGGAGGGGG GAGGCGACCC CGGGGCGGGC TCGGCGGGGC GGGGCGGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

pon:100436173

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	98.00	0.00e+00	811.00
IUUC-Apl-004107	Anas platyrhynchos	69.29	1.00e-131	462.00
IUUC-Aca-004354	Anolis carolinensis	73.63	1.00e-168	585.00
IUUC-Bta-012627	Bos taurus	98.47	0.00e+00	776.00
IUUC-Cja-018897	Callithrix jacchus	97.94	0.00e+00	783.00
IUUC-Cfa-020122	Canis familiaris	98.25	0.00e+00	811.00
IUUC-Cpo-022540	Cavia porcellus	97.19	0.00e+00	788.00
IUUC-Csa-023719	Chlorocebus sabaeus	99.48	0.00e+00	795.00
IUUC-Cho-024367	Choloepus hoffmanni	97.32	3.00e-172	597.00
IUUC-Dno-029021	Dasypus novemcinctus	97.95	0.00e+00	793.00
IUUC-Dor-030321	Dipodomys ordii	97.42	0.00e+00	784.00
IUUC-Ete-032955	Echinops telfairi	96.99	0.00e+00	778.00
IUUC-Eca-033485	Equus caballus	98.21	0.00e+00	768.00
IUUC-Fca-035389	Felis catus	97.94	0.00e+00	790.00
IUUC-Fal-037184	Ficedula albicollis	84.45	8.00e-143	499.00
IUUC-Gga-041014	Gallus gallus	77.34	2.00e-176	612.00
IUUC-Ggo-045585	Gorilla gorilla	99.74	0.00e+00	804.00
IUUC-Hsa-046344	Homo sapiens	99.74	0.00e+00	804.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	97.69	0.00e+00	791.00
IUUC-Lch-050131	Latimeria chalumnae	70.27	8.00e-168	583.00
IUUC-Loc-052807	Lepisosteus oculatus	54.33	3.00e-116	411.00
IUUC-Laf-053528	Loxodonta africana	97.95	0.00e+00	773.00
IUUC-Mcc-055665	Macaca mulatta	99.74	0.00e+00	804.00
IUUC-Meu-056054	Macropus eugenii	87.63	0.00e+00	697.00
IUUC-Mga-059326	Meleagris gallopavo	77.44	0.00e+00	630.00
IUUC-Mmr-060815	Microcebus murinus	96.68	0.00e+00	786.00
IUUC-Mdo-062000	Monodelphis domestica	90.59	0.00e+00	751.00
IUUC-Mmu-063927	Mus musculus	95.89	0.00e+00	778.00
IUUC-Mpu-065726	Mustela putorius furo	96.14	0.00e+00	775.00
IUUC-Mlu-067527	Myotis lucifugus	96.67	4.00e-119	420.00
IUUC-Nle-069680	Nomascus leucogenys	99.23	0.00e+00	795.00
IUUC-Opr-070356	Ochotona princeps	97.49	0.00e+00	801.00
IUUC-Oan-073647	Ornithorhynchus anatinus	83.94	3.00e-136	478.00
IUUC-Ocu-073973	Oryctolagus cuniculus	96.93	0.00e+00	783.00
IUUC-Oga-088797	Otolemur garnettii	98.72	0.00e+00	793.00
IUUC-Oar-089187	Ovis aries	98.47	0.00e+00	777.00
IUUC-Ptr-091317	Pan troglodytes	99.74	0.00e+00	803.00
IUUC-Pan-092694	Papio anubis	91.69	0.00e+00	685.00
IUUC-Psi-093392	Pelodiscus sinensis	79.40	0.00e+00	642.00
IUUC-Pca-100454	Procavia capensis	88.47	0.00e+00	719.00
IUUC-Pva-102986	Pteropus vampyrus	89.72	0.00e+00	727.00
IUUC-Rno-104931	Rattus norvegicus	94.59	0.00e+00	766.00
IUUC-Sha-106476	Sarcophilus harrisii	91.52	0.00e+00	745.00
IUUC-Ssc-115643	Sus scrofa	98.45	0.00e+00	789.00
IUUC-Tgu-117522	Taeniopygia guttata	64.20	4.00e-136	477.00
IUUC-Tsy-119301	Tarsius syrichta	99.25	0.00e+00	816.00
IUUC-Ttr-128683	Tursiops truncatus	98.45	0.00e+00	790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence