iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116364

Ensembl Protein ID

ENSSSCP00000010791.2

UniProt Accession

F1RK64; F1RK64_PIG

Genbank Protein ID

ENSSSCP00000010791

Protein Name

Protein HIRA

Genbank Nucleotide ID

CU618331

Gene Name

HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000010118.2	ENSSSCT00000011079.2	ENSSSCP00000010791.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-20	71.3	69	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNSgMYLASGGDDKLIMVWK 98
           8899******955699*************7 PP

Organism

Sus scrofa

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

RSMLRIFFSL FPGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENVP 60
KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFS SSGKLANVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATCGATGT TACGTATTTT TTTTTCTTTG TTCCCAGGCA AGCCAATTTT TTCAGTTGAT 60
ATTCACCCTG ACGGGACCAA GTTTGCAACT GGAGGACAAG GTATGTTCTG GAGGAACAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0043234--C:protein complex
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0007369--P:gastrulation
GO:0042692--P:muscle cell differentiation
GO:0001649--P:osteoblast differentiation
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	39.37	2.00e-85	310.00
IUUC-Aml-001723	Ailuropoda melanoleuca	95.85	0.00e+00	1758.00
IUUC-Atr-003132	Amborella trichopoda	40.98	2.00e-84	307.00
IUUC-Apl-003197	Anas platyrhynchos	82.48	0.00e+00	1580.00
IUUC-Aca-004733	Anolis carolinensis	81.97	0.00e+00	1546.00
IUUC-Aly-005446	Arabidopsis lyrata	34.83	5.00e-78	285.00
IUUC-Ath-007627	Arabidopsis thaliana	35.71	3.00e-82	300.00
IUUC-Ago-007766	Ashbya gossypii	31.30	5.00e-57	215.00
IUUC-Acl-008104	Aspergillus clavatus	29.25	2.00e-59	224.00
IUUC-Afl-008591	Aspergillus flavus	29.08	5.00e-60	226.00
IUUC-Afu-008781	Aspergillus fumigatus	33.07	1.00e-57	218.00
IUUC-Ani-009272	Aspergillus nidulans	28.96	1.00e-54	208.00
IUUC-Ang-009655	Aspergillus niger	33.25	1.00e-60	228.00
IUUC-Aor-010119	Aspergillus oryzae	29.08	1.00e-60	228.00
IUUC-Ate-010530	Aspergillus terreus	31.28	1.00e-53	204.00
IUUC-Ame-011147	Astyanax mexicanus	84.09	8.00e-46	174.00
IUUC-Bgr-012237	Blumeria graminis	33.33	9.00e-59	221.00
IUUC-Bta-013320	Bos taurus	91.71	0.00e+00	1771.00
IUUC-Bci-013795	Botrytis cinerea	33.51	1.00e-63	238.00
IUUC-Bdi-014075	Brachypodium distachyon	41.93	7.00e-88	318.00
IUUC-Bol-016440	Brassica oleracea	34.42	3.00e-84	306.00
IUUC-Bra-016651	Brassica rapa	39.79	2.00e-83	303.00
IUUC-Cel-018692	Caenorhabditis elegans	38.04	4.00e-73	269.00
IUUC-Cja-018987	Callithrix jacchus	94.46	0.00e+00	1665.00
IUUC-Cfa-020132	Canis familiaris	95.74	0.00e+00	1751.00
IUUC-Cpo-021484	Cavia porcellus	94.04	0.00e+00	1726.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	36.00	8.00e-59	222.00
IUUC-Csa-023081	Chlorocebus sabaeus	95.03	0.00e+00	1734.00
IUUC-Cin-025182	Ciona intestinalis	54.64	4.00e-150	525.00
IUUC-Csv-026154	Ciona savignyi	56.12	5.00e-147	514.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	29.92	9.00e-61	228.00
IUUC-Cne-026891	Cryptococcus neoformans	40.96	8.00e-80	291.00
IUUC-Cme-027349	Cyanidioschyzon merolae	28.86	2.00e-52	201.00
IUUC-Dre-027655	Danio rerio	68.51	0.00e+00	1310.00
IUUC-Dno-029557	Dasypus novemcinctus	83.29	0.00e+00	1075.00
IUUC-Dor-030687	Dipodomys ordii	85.65	0.00e+00	726.00
IUUC-Dse-031334	Dothistroma septosporum	30.69	9.00e-59	221.00
IUUC-Dme-031746	Drosophila melanogaster	55.34	5.00e-152	531.00
IUUC-Ete-032384	Echinops telfairi	86.98	0.00e+00	1590.00
IUUC-Eca-033430	Equus caballus	96.13	0.00e+00	1744.00
IUUC-Fca-036121	Felis catus	95.34	0.00e+00	1744.00
IUUC-Fal-036817	Ficedula albicollis	82.17	0.00e+00	1586.00
IUUC-Fox-037906	Fusarium oxysporum	34.84	7.00e-66	244.00
IUUC-Fso-038409	Fusarium solani	33.58	6.00e-64	239.00
IUUC-Gmo-039151	Gadus morhua	85.79	0.00e+00	676.00
IUUC-Ggr-040016	Gaeumannomyces graminis	32.18	8.00e-67	248.00
IUUC-Gga-040936	Gallus gallus	83.42	0.00e+00	1640.00
IUUC-Gac-041405	Gasterosteus aculeatus	61.98	0.00e+00	1155.00
IUUC-Gma-044252	Glycine max	35.96	4.00e-86	313.00
IUUC-Ggo-045430	Gorilla gorilla	94.54	0.00e+00	1727.00
IUUC-Hsa-046442	Homo sapiens	94.54	0.00e+00	1726.00
IUUC-Hvu-047587	Hordeum vulgare	36.68	9.00e-80	291.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	99.33	3.00e-175	606.00
IUUC-Kpa-049145	Komagataella pastoris	31.11	1.00e-58	221.00
IUUC-Lch-050474	Latimeria chalumnae	74.39	0.00e+00	1375.00
IUUC-Lpe-051209	Leersia perrieri	35.31	8.00e-80	291.00
IUUC-Loc-052119	Lepisosteus oculatus	71.04	0.00e+00	1321.00
IUUC-Lma-053237	Leptosphaeria maculans	33.13	2.00e-64	240.00
IUUC-Laf-053718	Loxodonta africana	92.85	0.00e+00	1704.00
IUUC-Mcc-055621	Macaca mulatta	94.36	0.00e+00	1657.00
IUUC-Meu-055914	Macropus eugenii	78.10	0.00e+00	1407.00
IUUC-Mor-057090	Magnaporthe oryzae	34.09	4.00e-64	239.00
IUUC-Mpo-057364	Magnaporthe poae	32.79	2.00e-69	257.00
IUUC-Mtr-057744	Medicago truncatula	37.68	8.00e-88	318.00
IUUC-Mla-058914	Melampsora laricipopulina	36.16	4.00e-80	292.00
IUUC-Mga-060181	Meleagris gallopavo	81.66	0.00e+00	1605.00
IUUC-Mvi-060432	Microbotryum violaceum	38.24	3.00e-72	266.00
IUUC-Mmr-060871	Microcebus murinus	94.14	0.00e+00	1773.00
IUUC-Mdo-062301	Monodelphis domestica	84.77	0.00e+00	1568.00
IUUC-Mmu-063888	Mus musculus	92.94	0.00e+00	1699.00
IUUC-Mac-065137	Musa acuminata	37.77	2.00e-85	310.00
IUUC-Mpu-066732	Mustela putorius furo	95.56	0.00e+00	1797.00
IUUC-Mlu-067542	Myotis lucifugus	94.69	0.00e+00	1711.00
IUUC-Nfi-068396	Neosartorya fischeri	33.71	1.00e-57	218.00
IUUC-Ncr-068842	Neurospora crassa	32.25	1.00e-64	241.00
IUUC-Nle-070156	Nomascus leucogenys	94.74	0.00e+00	1743.00
IUUC-Opr-070808	Ochotona princeps	92.69	0.00e+00	1387.00
IUUC-Ont-072105	Oreochromis niloticus	66.90	0.00e+00	1283.00
IUUC-Ocu-074962	Oryctolagus cuniculus	94.26	0.00e+00	1741.00
IUUC-Oba-075178	Oryza barthii	41.41	1.00e-86	314.00
IUUC-Obr-076399	Oryza brachyantha	36.77	1.00e-87	317.00
IUUC-Ogu-078797	Oryza glumaepatula	41.41	1.00e-86	314.00
IUUC-Oin-080085	Oryza indica	40.23	9.00e-78	285.00
IUUC-Olo-081048	Oryza longistaminata	40.39	7.00e-66	246.00
IUUC-Ome-081324	Oryza meridionalis	41.41	1.00e-86	314.00
IUUC-Oni-082548	Oryza nivara	41.41	1.00e-86	314.00
IUUC-Opu-084008	Oryza punctata	41.41	8.00e-87	315.00
IUUC-Oru-084339	Oryza rufipogon	41.15	3.00e-86	313.00
IUUC-Osa-085782	Oryza sativa	41.15	3.00e-86	313.00
IUUC-Ola-087302	Oryzias latipes	67.19	0.00e+00	776.00
IUUC-Olu-087611	Ostreococcus lucimarinus	36.20	3.00e-87	316.00
IUUC-Oga-087935	Otolemur garnettii	93.98	0.00e+00	1727.00
IUUC-Oar-089229	Ovis aries	69.98	0.00e+00	1063.00
IUUC-Ptr-090715	Pan troglodytes	94.64	0.00e+00	1727.00
IUUC-Pan-092318	Papio anubis	95.14	0.00e+00	1746.00
IUUC-Psi-094053	Pelodiscus sinensis	82.45	0.00e+00	1587.00
IUUC-Pno-094985	Phaeosphaeria nodorum	33.25	8.00e-57	215.00
IUUC-Ppa-095819	Physcomitrella patens	35.07	2.00e-85	310.00
IUUC-Pfo-096857	Poecilia formosa	65.72	0.00e+00	1241.00
IUUC-Pab-098047	Pongo abelii	94.84	0.00e+00	1732.00
IUUC-Pop-099587	Populus trichocarpa	36.70	1.00e-85	311.00
IUUC-Pca-100558	Procavia capensis	90.63	0.00e+00	713.00
IUUC-Ppe-101261	Prunus persica	37.18	4.00e-87	316.00
IUUC-Pva-102683	Pteropus vampyrus	95.53	0.00e+00	1760.00
IUUC-Pgr-103660	Puccinia graminis	40.92	2.00e-73	270.00
IUUC-Ptt-103900	Puccinia triticina	42.24	4.00e-75	275.00
IUUC-Pte-104209	Pyrenophora teres	33.91	4.00e-61	229.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	32.51	3.00e-60	227.00
IUUC-Rno-105137	Rattus norvegicus	92.58	0.00e+00	1734.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.38	6.00e-59	222.00
IUUC-Sha-107514	Sarcophilus harrisii	79.47	0.00e+00	1458.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	35.38	8.00e-77	281.00
IUUC-Spo-108162	Schizosaccharomyces pombe	36.68	8.00e-76	278.00
IUUC-Smo-109186	Selaginella moellendorffii	40.83	3.00e-86	313.00
IUUC-Sit-109980	Setaria italica	37.07	6.00e-89	322.00
IUUC-Sly-111547	Solanum lycopersicum	37.37	9.00e-89	321.00
IUUC-Stu-112705	Solanum tuberosum	37.37	4.00e-89	322.00
IUUC-Sar-113222	Sorex araneus	88.95	0.00e+00	1516.00
IUUC-Sbi-114272	Sorghum bicolor	37.07	4.00e-89	322.00
IUUC-Sre-115061	Sporisorium reilianum	27.15	5.00e-91	328.00
IUUC-Tgu-116645	Taeniopygia guttata	82.29	0.00e+00	1604.00
IUUC-Tru-117590	Takifugu rubripes	65.93	0.00e+00	1259.00
IUUC-Tsy-119212	Tarsius syrichta	90.48	0.00e+00	978.00
IUUC-Tni-119915	Tetraodon nigroviridis	66.36	0.00e+00	1231.00
IUUC-Tca-121765	Theobroma cacao	36.55	2.00e-86	314.00
IUUC-Tre-121887	Trichoderma reesei	29.85	6.00e-57	216.00
IUUC-Tvi-122262	Trichoderma virens	33.76	1.00e-56	214.00
IUUC-Tae-124148	Triticum aestivum	43.43	2.00e-34	140.00
IUUC-Tur-126483	Triticum urartu	42.71	4.00e-89	322.00
IUUC-Tme-127202	Tuber melanosporum	31.11	3.00e-54	206.00
IUUC-Tbe-127350	Tupaia belangeri	83.66	0.00e+00	648.00
IUUC-Ttr-129077	Tursiops truncatus	92.05	0.00e+00	1780.00
IUUC-Uma-129465	Ustilago maydis	34.04	6.00e-78	285.00
IUUC-Vda-129844	Verticillium dahliae	34.19	4.00e-63	236.00
IUUC-Vvi-131397	Vitis vinifera	37.42	5.00e-88	319.00
IUUC-Xtr-132057	Xenopus tropicalis	75.00	0.00e+00	1398.00
IUUC-Xma-134139	Xiphophorus maculatus	67.36	0.00e+00	802.00
IUUC-Yli-134424	Yarrowia lipolytica	31.96	3.00e-63	236.00
IUUC-Zma-135839	Zea mays	36.71	9.00e-88	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence