iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091393

Ensembl Protein ID

ENSPTRP00000041340.5

UniProt Accession

H2R0V7; H2R0V7_PANTR

Genbank Protein ID

JAA18704.1

Protein Name

Lysosomal trafficking regulator

Genbank Nucleotide ID

AACZ03003067

Gene Name

LYST

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000002134.6	ENSPTRT00000049627.5	ENSPTRP00000041340.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-07	29.5	3615	3647

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHt+++t+l f   +  +l+s s+Dgt+ +WDl 
   Q: 3615 GHTEEITSL-FvckPYSILISVSRDGTCIIWDLN 3647
           8********.99875578**************85 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSTDSNSLAR EFLTDVNRLC NAVVQRVEAR EEEEEETHMA TLGQYLVHGR GFLLLTKLNS 60
IIDQALTCRE ELLTLLLSLL PLVWKIPVQE EKATDFNLPL SADIILTKEK NSSSQRSTQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGCGGCG GCGGCAGCGG CGTCGGCTCG GGGTTCTCCG GGAGAGGGGG AGCGCGCGGC 60
GGCCGCAGCT GCCACAAACC AGGTAAAGGC GGCCGCCGGG CGCCGACGCT GCCGGCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR011989--ARM-like
IPR000409--BEACH_dom
IPR030464--LYST
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02138--Beach
PF14844--PH_BEACH
PF00400--WD40

SMART

SM01026--Beach
SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0032510--P:endosome to lysosome transport via multivesicular body sorting pathway
GO:0007040--P:lysosome organization
GO:0042267--P:natural killer cell mediated cytotoxicity
GO:0043473--P:pigmentation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002188	Ailuropoda melanoleuca	90.60	0.00e+00	6983.00
IUUC-Apl-003779	Anas platyrhynchos	72.87	0.00e+00	5444.00
IUUC-Ame-010834	Astyanax mexicanus	61.46	0.00e+00	4501.00
IUUC-Bta-013274	Bos taurus	90.37	0.00e+00	6882.00
IUUC-Cja-019682	Callithrix jacchus	96.40	0.00e+00	7346.00
IUUC-Cfa-020625	Canis familiaris	90.27	0.00e+00	6815.00
IUUC-Cpo-022515	Cavia porcellus	86.05	0.00e+00	6489.00
IUUC-Csa-023804	Chlorocebus sabaeus	97.29	0.00e+00	7388.00
IUUC-Cin-025176	Ciona intestinalis	44.63	2.00e-85	308.00
IUUC-Csv-026108	Ciona savignyi	53.27	0.00e+00	711.00
IUUC-Dre-027544	Danio rerio	62.76	0.00e+00	3345.00
IUUC-Dno-029030	Dasypus novemcinctus	88.13	0.00e+00	6716.00
IUUC-Dor-031065	Dipodomys ordii	81.65	0.00e+00	2903.00
IUUC-Eca-034391	Equus caballus	90.77	0.00e+00	6930.00
IUUC-Fal-037194	Ficedula albicollis	71.73	0.00e+00	5385.00
IUUC-Gmo-039256	Gadus morhua	74.35	0.00e+00	2306.00
IUUC-Gga-040318	Gallus gallus	72.56	0.00e+00	5405.00
IUUC-Gac-042425	Gasterosteus aculeatus	64.35	0.00e+00	3492.00
IUUC-Ggo-045550	Gorilla gorilla	98.66	0.00e+00	7490.00
IUUC-Hsa-046612	Homo sapiens	99.08	0.00e+00	7536.00
IUUC-Laf-054133	Loxodonta africana	89.52	0.00e+00	6751.00
IUUC-Mcc-055373	Macaca mulatta	97.50	0.00e+00	7444.00
IUUC-Mga-059475	Meleagris gallopavo	70.61	0.00e+00	5241.00
IUUC-Mmr-061795	Microcebus murinus	93.42	0.00e+00	7052.00
IUUC-Mlu-067930	Myotis lucifugus	85.02	0.00e+00	3764.00
IUUC-Nle-069205	Nomascus leucogenys	97.16	0.00e+00	7337.00
IUUC-Ont-071764	Oreochromis niloticus	61.80	0.00e+00	4386.00
IUUC-Ocu-074479	Oryctolagus cuniculus	90.27	0.00e+00	6857.00
IUUC-Pan-092369	Papio anubis	97.42	0.00e+00	7405.00
IUUC-Pfo-096100	Poecilia formosa	61.00	0.00e+00	4393.00
IUUC-Pab-098733	Pongo abelii	97.19	0.00e+00	7344.00
IUUC-Pca-100429	Procavia capensis	77.83	0.00e+00	2525.00
IUUC-Sha-106595	Sarcophilus harrisii	73.76	0.00e+00	5387.00
IUUC-Sar-113059	Sorex araneus	78.09	0.00e+00	1854.00
IUUC-Ssc-115879	Sus scrofa	84.08	0.00e+00	6177.00
IUUC-Tru-118616	Takifugu rubripes	60.18	0.00e+00	4360.00
IUUC-Tsy-119568	Tarsius syrichta	86.49	0.00e+00	5613.00
IUUC-Tni-120782	Tetraodon nigroviridis	60.18	0.00e+00	4345.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence