iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012923

Ensembl Protein ID

ENSBTAP00000028744.5

UniProt Accession

Q3MHH0; A6QR04; DCA12_BOVIN

Genbank Protein ID

AAI05242.1; AAI50063.1

Protein Name

DDB1- and CUL4-associated factor 12; WD repeat-containing protein 40A

Genbank Nucleotide ID

BC105241; BC150062

Gene Name

DCAF12; WDR40A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021573.5	ENSBTAT00000028744.5	ENSBTAP00000028744.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-24	83.3	182	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+d+++++a+ sdt+ vsGs+Dg++ +W+++++vl+ks
   Q: 182  GHKDWIFSIAWiSDTMAVSGSRDGSMGLWEVTDDVLTKS 220
           8**********************************9986 PP

Organism

Bos taurus

Functional Description
(View)

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MARKAVSRKR KAPALPGAGS DAQDPQFGWD HSLHKRKRLP PVKRSLVYYL KNREVRLQNE 60
TSYSRVLHGY AAQQLPSLLK EREFHLGTLN KVFASQWLNH RQVVCGTKCN TLFVVDVQTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGGAGGGG GTGTTTTGGT TCCAGCCGCT CGCCGTCCTT TCTAGACTTG GTCGTCTACA 60
AGCTTCGGGT TCCTGTCTCC CCTTCCCTTT CCCTTCCCTT TCCCTGCCCC GGTCCTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm

KEGG

bta:525161

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002102	Ailuropoda melanoleuca	97.57	0.00e+00	923.00
IUUC-Apl-003794	Anas platyrhynchos	88.30	0.00e+00	826.00
IUUC-Aca-004264	Anolis carolinensis	85.58	0.00e+00	742.00
IUUC-Ame-011254	Astyanax mexicanus	68.65	0.00e+00	665.00
IUUC-Cja-019590	Callithrix jacchus	98.25	0.00e+00	702.00
IUUC-Cfa-021123	Canis familiaris	98.01	0.00e+00	927.00
IUUC-Cpo-021733	Cavia porcellus	92.98	0.00e+00	660.00
IUUC-Csa-023339	Chlorocebus sabaeus	97.79	0.00e+00	926.00
IUUC-Cho-024837	Choloepus hoffmanni	76.09	9.00e-147	513.00
IUUC-Dre-027571	Danio rerio	69.94	0.00e+00	672.00
IUUC-Dno-029106	Dasypus novemcinctus	97.14	0.00e+00	892.00
IUUC-Dor-030162	Dipodomys ordii	62.30	6.00e-138	483.00
IUUC-Dme-031774	Drosophila melanogaster	39.00	2.00e-79	289.00
IUUC-Ete-033140	Echinops telfairi	72.82	1.00e-114	405.00
IUUC-Eca-034316	Equus caballus	97.57	0.00e+00	926.00
IUUC-Eeu-034641	Erinaceus europaeus	90.06	0.00e+00	637.00
IUUC-Fca-036150	Felis catus	97.90	0.00e+00	880.00
IUUC-Fal-036636	Ficedula albicollis	89.89	0.00e+00	846.00
IUUC-Gmo-038736	Gadus morhua	73.98	0.00e+00	662.00
IUUC-Gga-040896	Gallus gallus	84.21	0.00e+00	760.00
IUUC-Gac-042623	Gasterosteus aculeatus	71.89	0.00e+00	668.00
IUUC-Ggo-044968	Gorilla gorilla	98.25	0.00e+00	704.00
IUUC-Hsa-046020	Homo sapiens	98.01	0.00e+00	927.00
IUUC-Itr-048766	Ictidomys tridecemlineatus	97.35	0.00e+00	924.00
IUUC-Lch-050244	Latimeria chalumnae	81.58	0.00e+00	776.00
IUUC-Loc-052777	Lepisosteus oculatus	75.49	0.00e+00	688.00
IUUC-Laf-054505	Loxodonta africana	95.58	0.00e+00	910.00
IUUC-Mcc-055187	Macaca mulatta	97.90	0.00e+00	878.00
IUUC-Meu-056026	Macropus eugenii	90.87	0.00e+00	807.00
IUUC-Mga-059618	Meleagris gallopavo	57.89	1.00e-127	449.00
IUUC-Mmr-061121	Microcebus murinus	90.79	0.00e+00	828.00
IUUC-Mdo-062823	Monodelphis domestica	94.04	0.00e+00	872.00
IUUC-Mmu-064332	Mus musculus	96.91	0.00e+00	917.00
IUUC-Mpu-066157	Mustela putorius furo	98.01	0.00e+00	927.00
IUUC-Mlu-067146	Myotis lucifugus	95.58	0.00e+00	909.00
IUUC-Nle-069179	Nomascus leucogenys	95.81	0.00e+00	896.00
IUUC-Opr-070970	Ochotona princeps	95.03	0.00e+00	678.00
IUUC-Ont-072013	Oreochromis niloticus	69.26	0.00e+00	633.00
IUUC-Oan-072810	Ornithorhynchus anatinus	85.71	2.00e-62	231.00
IUUC-Ocu-074646	Oryctolagus cuniculus	96.91	0.00e+00	918.00
IUUC-Ola-087062	Oryzias latipes	70.15	0.00e+00	658.00
IUUC-Olu-087756	Ostreococcus lucimarinus	27.66	4.00e-16	79.00
IUUC-Oga-089071	Otolemur garnettii	97.79	0.00e+00	929.00
IUUC-Oar-089522	Ovis aries	99.78	0.00e+00	943.00
IUUC-Ptr-091042	Pan troglodytes	93.16	0.00e+00	875.00
IUUC-Pan-092832	Papio anubis	97.57	0.00e+00	924.00
IUUC-Psi-093131	Pelodiscus sinensis	92.56	0.00e+00	828.00
IUUC-Pma-094151	Petromyzon marinus	57.71	9.00e-61	226.00
IUUC-Pfo-096970	Poecilia formosa	69.53	0.00e+00	660.00
IUUC-Pab-098019	Pongo abelii	98.01	0.00e+00	927.00
IUUC-Pca-100401	Procavia capensis	78.36	2.00e-153	535.00
IUUC-Pva-103128	Pteropus vampyrus	97.13	0.00e+00	924.00
IUUC-Rno-105945	Rattus norvegicus	84.33	0.00e+00	763.00
IUUC-Sha-107518	Sarcophilus harrisii	95.34	0.00e+00	682.00
IUUC-Smo-108742	Selaginella moellendorffii	32.53	3.00e-51	195.00
IUUC-Sar-113026	Sorex araneus	74.83	0.00e+00	658.00
IUUC-Ssc-115446	Sus scrofa	96.49	0.00e+00	849.00
IUUC-Tgu-117240	Taeniopygia guttata	82.95	0.00e+00	659.00
IUUC-Tru-118560	Takifugu rubripes	68.78	0.00e+00	661.00
IUUC-Tsy-119344	Tarsius syrichta	90.07	0.00e+00	841.00
IUUC-Tni-119714	Tetraodon nigroviridis	72.07	0.00e+00	674.00
IUUC-Tbe-127634	Tupaia belangeri	97.62	5.00e-96	344.00
IUUC-Ttr-128503	Tursiops truncatus	96.91	0.00e+00	918.00
IUUC-Vpa-130126	Vicugna pacos	96.52	3.00e-165	574.00
IUUC-Xtr-132744	Xenopus tropicalis	51.21	4.00e-109	387.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence