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Tag Content
iUUCD ID IUUC-Mvi-060240
Ensembl Protein ID MVLG_06033T0
UniProt Accession U5HG12; U5HG12_USTV1
Genbank Protein ID KDE03471.1
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AEIJ01000674
Gene Name MVLG_06033
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
MVLG_06033 MVLG_06033T0 MVLG_06033T0
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-30 102.5 96 129
UBD/Beta-Prp 8.30e-69 230.6 12 299
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
    H d ++cla ++ l+++GsdD tik+WD+ +g
   Q: 96 HPDYIRCLAVhPTqSLVLTGSDDMTIKLWDWEKG 129
    99********988799**************8765 PP
   


   UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsps 105
    +++++++++++p +++l++g ++g ++++ ++tg ++++++ e +v++v+f+ ++++++ gs+D +++v++++tg+ v +l++h d++++l+++p+
   Q: 12 RSDRVKSLDIHPTEPWLIAGLYTGNVIIYHIDTGVVIKTFEVTEVPVRCVRFIARRNWFICGSDDFHLRVFNYNTGEKVTALEAHPDYIRCLAVHPT 108
    67899******************************************************************************************** PP
   S: 106 gdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgs 199
    ++ +++Gs+d ti++wd+e+g++ ++++gh++ ++ ++++p++ n ++s++lDrtv++W+l ++ tl h++ v+ +++ + g ++lv+ +
   Q: 109 QSLVLTGSDDMTIKLWDWEKGWKCIQVFEGHTHYIMNLSFNPKDaNTFASACLDRTVKVWSLGSAAANFTLDA-HEKGVNYVEYYHGGdkPYLVTTG 204
    *********************98888*********************************************98.*********9988888******* PP
   S: 200 ldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkk 296
    +d+++k+wd+ +++c++tl+gh++nv+ f+p +l+sgs+Dg+++iW + + l +tl + ++ +++a+ s ++n v++++d + + kl +
   Q: 205 DDRQIKIWDYLSKSCIQTLEGHSSNVSFAIFHPSLPILISGSEDGTVKIWHSSTYRLENTLDYGLERAWCIAY-SKKGND-VAFGFDEGAVVVKLGR 299
    *************************************************************************.444554.4455666666666655 PP
   

Organism Microbotryum violaceum
Functional Description
(View)

Functional Description



     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MLLEINRKLL ARSDRVKSLD IHPTEPWLIA GLYTGNVIIY HIDTGVVIKT FEVTEVPVRC 60
VRFIARRNWF ICGSDDFHLR VFNYNTGEKV TALEAHPDYI RCLAVHPTQS LVLTGSDDMT 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mvi-060240|E3,WD_repeat;UBD,Beta-Prp|Microbotryum violaceum
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCCACTCAG CCACCGACGA CCTACACCAC CTCGTTACGT CTAATCTTGG GAGCCTCCAA 60
CGTGATCTCG CTCTTGCCTG TTCTTTTCCT TCCTCCCGGC GTGCGAGCTA GACCCCCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mvi-060240|E3,WD_repeat;UBD,Beta-Prp|Microbotryum violaceum
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 44.68 0.00e+00 765.00
IUUC-Aml-002154 Ailuropoda melanoleuca 49.94 0.00e+00 936.00
IUUC-Atr-003090 Amborella trichopoda 50.77 0.00e+00 892.00
IUUC-Apl-003976 Anas platyrhynchos 52.05 0.00e+00 927.00
IUUC-Aca-004301 Anolis carolinensis 50.23 0.00e+00 930.00
IUUC-Aly-005643 Arabidopsis lyrata 52.40 0.00e+00 895.00
IUUC-Ath-007630 Arabidopsis thaliana 52.99 0.00e+00 908.00
IUUC-Ago-007914 Ashbya gossypii 48.03 0.00e+00 778.00
IUUC-Acl-008237 Aspergillus clavatus 57.97 0.00e+00 996.00
IUUC-Afl-008535 Aspergillus flavus 58.48 0.00e+00 968.00
IUUC-Afu-008845 Aspergillus fumigatus 55.22 0.00e+00 975.00
IUUC-Ani-009135 Aspergillus nidulans 54.70 0.00e+00 962.00
IUUC-Ang-009654 Aspergillus niger 61.04 0.00e+00 885.00
IUUC-Aor-009939 Aspergillus oryzae 58.44 0.00e+00 1015.00
IUUC-Ate-010355 Aspergillus terreus 58.09 0.00e+00 962.00
IUUC-Ame-010922 Astyanax mexicanus 46.87 0.00e+00 797.00
IUUC-Bgr-012249 Blumeria graminis 57.39 0.00e+00 971.00
IUUC-Bta-013579 Bos taurus 52.30 0.00e+00 837.00
IUUC-Bci-013866 Botrytis cinerea 56.74 0.00e+00 948.00
IUUC-Bdi-015046 Brachypodium distachyon 50.25 0.00e+00 885.00
IUUC-Bol-016271 Brassica oleracea 53.41 0.00e+00 919.00
IUUC-Bra-017758 Brassica rapa 52.56 0.00e+00 907.00
IUUC-Cel-018387 Caenorhabditis elegans 48.58 0.00e+00 840.00
IUUC-Cja-019145 Callithrix jacchus 49.94 0.00e+00 936.00
IUUC-Cfa-020564 Canis familiaris 49.94 0.00e+00 935.00
IUUC-Cpo-022201 Cavia porcellus 49.94 0.00e+00 936.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 52.10 0.00e+00 862.00
IUUC-Csa-023383 Chlorocebus sabaeus 56.18 0.00e+00 731.00
IUUC-Cho-024454 Choloepus hoffmanni 49.79 0.00e+00 800.00
IUUC-Cin-025681 Ciona intestinalis 50.62 0.00e+00 858.00
IUUC-Csv-026012 Ciona savignyi 51.09 0.00e+00 850.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 53.37 0.00e+00 848.00
IUUC-Cne-026986 Cryptococcus neoformans 64.45 0.00e+00 1115.00
IUUC-Cme-027219 Cyanidioschyzon merolae 45.52 0.00e+00 784.00
IUUC-Dre-027846 Danio rerio 50.61 0.00e+00 921.00
IUUC-Dor-030462 Dipodomys ordii 51.67 0.00e+00 749.00
IUUC-Dse-031268 Dothistroma septosporum 57.47 0.00e+00 986.00
IUUC-Dme-031791 Drosophila melanogaster 52.55 0.00e+00 889.00
IUUC-Ete-033166 Echinops telfairi 49.55 5.00e-175 606.00
IUUC-Eca-034180 Equus caballus 49.19 0.00e+00 900.00
IUUC-Eeu-035086 Erinaceus europaeus 39.21 6.00e-96 343.00
IUUC-Fca-036265 Felis catus 50.59 0.00e+00 934.00
IUUC-Fal-037202 Ficedula albicollis 51.16 0.00e+00 882.00
IUUC-Fox-037711 Fusarium oxysporum 56.79 0.00e+00 887.00
IUUC-Fso-038268 Fusarium solani 56.76 0.00e+00 880.00
IUUC-Gmo-039046 Gadus morhua 51.81 0.00e+00 924.00
IUUC-Ggr-039863 Gaeumannomyces graminis 56.55 0.00e+00 914.00
IUUC-Gga-041112 Gallus gallus 50.97 0.00e+00 929.00
IUUC-Gac-041733 Gasterosteus aculeatus 51.68 0.00e+00 907.00
IUUC-Gma-042910 Glycine max 51.01 0.00e+00 924.00
IUUC-Ggo-044984 Gorilla gorilla 50.59 0.00e+00 934.00
IUUC-Hsa-046698 Homo sapiens 50.59 0.00e+00 935.00
IUUC-Hvu-047669 Hordeum vulgare 56.66 2.00e-133 467.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 50.06 0.00e+00 935.00
IUUC-Kpa-049265 Komagataella pastoris 50.19 0.00e+00 882.00
IUUC-Lch-050473 Latimeria chalumnae 50.06 0.00e+00 931.00
IUUC-Lpe-051579 Leersia perrieri 51.11 0.00e+00 893.00
IUUC-Loc-052675 Lepisosteus oculatus 50.59 0.00e+00 932.00
IUUC-Lma-053218 Leptosphaeria maculans 56.90 0.00e+00 966.00
IUUC-Laf-053757 Loxodonta africana 50.06 0.00e+00 932.00
IUUC-Mcc-054859 Macaca mulatta 49.94 0.00e+00 936.00
IUUC-Meu-056174 Macropus eugenii 41.67 2.00e-82 299.00
IUUC-Mor-057264 Magnaporthe oryzae 57.84 0.00e+00 910.00
IUUC-Mpo-057538 Magnaporthe poae 56.18 0.00e+00 929.00
IUUC-Mtr-058310 Medicago truncatula 50.56 0.00e+00 921.00
IUUC-Mla-058937 Melampsora laricipopulina 69.94 0.00e+00 1178.00
IUUC-Mga-059875 Meleagris gallopavo 50.12 0.00e+00 926.00
IUUC-Mmr-061261 Microcebus murinus 49.94 0.00e+00 935.00
IUUC-Mdo-062076 Monodelphis domestica 50.89 0.00e+00 937.00
IUUC-Mmu-063324 Mus musculus 49.83 0.00e+00 934.00
IUUC-Mac-064636 Musa acuminata 51.27 0.00e+00 898.00
IUUC-Mpu-065961 Mustela putorius furo 50.59 0.00e+00 934.00
IUUC-Mlu-067059 Myotis lucifugus 49.60 0.00e+00 910.00
IUUC-Nfi-068277 Neosartorya fischeri 55.52 0.00e+00 973.00
IUUC-Ncr-068659 Neurospora crassa 54.45 0.00e+00 942.00
IUUC-Nle-069034 Nomascus leucogenys 49.94 0.00e+00 937.00
IUUC-Opr-070334 Ochotona princeps 53.90 0.00e+00 872.00
IUUC-Ont-071563 Oreochromis niloticus 51.93 0.00e+00 927.00
IUUC-Oan-073416 Ornithorhynchus anatinus 51.68 0.00e+00 888.00
IUUC-Ocu-074522 Oryctolagus cuniculus 49.94 0.00e+00 932.00
IUUC-Oba-075760 Oryza barthii 50.12 0.00e+00 874.00
IUUC-Obr-076163 Oryza brachyantha 50.12 0.00e+00 892.00
IUUC-Ogl-077450 Oryza glaberrima 51.10 0.00e+00 902.00
IUUC-Ogu-078994 Oryza glumaepatula 50.12 0.00e+00 872.00
IUUC-Oin-079856 Oryza indica 51.23 0.00e+00 886.00
IUUC-Olo-080731 Oryza longistaminata 50.57 0.00e+00 862.00
IUUC-Ome-081554 Oryza meridionalis 47.67 0.00e+00 810.00
IUUC-Oni-082324 Oryza nivara 50.12 0.00e+00 873.00
IUUC-Opu-083400 Oryza punctata 47.16 0.00e+00 867.00
IUUC-Oru-084829 Oryza rufipogon 50.12 0.00e+00 874.00
IUUC-Osa-086026 Oryza sativa 51.10 0.00e+00 903.00
IUUC-Ola-087245 Oryzias latipes 51.43 0.00e+00 922.00
IUUC-Olu-087655 Ostreococcus lucimarinus 52.11 0.00e+00 892.00
IUUC-Oga-088163 Otolemur garnettii 49.08 0.00e+00 898.00
IUUC-Oar-089842 Ovis aries 49.83 0.00e+00 933.00
IUUC-Ptr-090501 Pan troglodytes 49.94 0.00e+00 935.00
IUUC-Pan-092011 Papio anubis 49.94 0.00e+00 936.00
IUUC-Psi-093308 Pelodiscus sinensis 52.18 0.00e+00 929.00
IUUC-Pma-094695 Petromyzon marinus 50.26 0.00e+00 838.00
IUUC-Pno-094785 Phaeosphaeria nodorum 60.69 4.00e-111 393.00
IUUC-Ppa-095911 Physcomitrella patens 51.13 0.00e+00 921.00
IUUC-Pfo-096587 Poecilia formosa 51.68 0.00e+00 923.00
IUUC-Pab-097926 Pongo abelii 48.56 0.00e+00 868.00
IUUC-Pop-099634 Populus trichocarpa 52.80 0.00e+00 917.00
IUUC-Pca-100965 Procavia capensis 49.02 0.00e+00 900.00
IUUC-Ppe-101470 Prunus persica 53.90 0.00e+00 929.00
IUUC-Pva-102451 Pteropus vampyrus 50.91 0.00e+00 741.00
IUUC-Pgr-103453 Puccinia graminis 71.39 0.00e+00 1240.00
IUUC-Ptt-103868 Puccinia triticina 71.52 0.00e+00 1239.00
IUUC-Pte-104274 Pyrenophora teres 58.39 0.00e+00 1006.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 57.77 0.00e+00 959.00
IUUC-Rno-105979 Rattus norvegicus 45.18 0.00e+00 697.00
IUUC-Sce-106269 Saccharomyces cerevisiae 49.12 0.00e+00 791.00
IUUC-Sha-106905 Sarcophilus harrisii 50.89 0.00e+00 937.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 49.18 0.00e+00 865.00
IUUC-Spo-108299 Schizosaccharomyces pombe 49.87 0.00e+00 876.00
IUUC-Smo-108695 Selaginella moellendorffii 52.26 0.00e+00 909.00
IUUC-Sit-110239 Setaria italica 49.42 0.00e+00 909.00
IUUC-Sly-111775 Solanum lycopersicum 52.96 0.00e+00 910.00
IUUC-Stu-112906 Solanum tuberosum 53.08 0.00e+00 831.00
IUUC-Sar-113472 Sorex araneus 50.49 0.00e+00 680.00
IUUC-Sbi-114052 Sorghum bicolor 51.59 0.00e+00 901.00
IUUC-Sre-115040 Sporisorium reilianum 65.32 0.00e+00 1145.00
IUUC-Ssc-115593 Sus scrofa 49.83 0.00e+00 934.00
IUUC-Tgu-117239 Taeniopygia guttata 51.93 0.00e+00 928.00
IUUC-Tru-118025 Takifugu rubripes 51.68 0.00e+00 925.00
IUUC-Tsy-118824 Tarsius syrichta 49.76 0.00e+00 686.00
IUUC-Tni-120142 Tetraodon nigroviridis 51.68 0.00e+00 919.00
IUUC-Tca-121613 Theobroma cacao 51.30 0.00e+00 930.00
IUUC-Tre-122072 Trichoderma reesei 56.06 0.00e+00 937.00
IUUC-Tvi-122546 Trichoderma virens 55.69 0.00e+00 937.00
IUUC-Tae-125395 Triticum aestivum 50.67 0.00e+00 899.00
IUUC-Tur-126283 Triticum urartu 45.20 0.00e+00 768.00
IUUC-Tme-127041 Tuber melanosporum 56.69 0.00e+00 1003.00
IUUC-Tbe-127770 Tupaia belangeri 53.18 0.00e+00 775.00
IUUC-Ttr-129294 Tursiops truncatus 49.83 0.00e+00 932.00
IUUC-Uma-129351 Ustilago maydis 63.98 0.00e+00 1143.00
IUUC-Vda-129716 Verticillium dahliae 56.79 0.00e+00 968.00
IUUC-Vpa-130037 Vicugna pacos 42.89 1.00e-105 375.00
IUUC-Vvi-131689 Vitis vinifera 53.42 0.00e+00 915.00
IUUC-Xtr-132633 Xenopus tropicalis 51.81 0.00e+00 927.00
IUUC-Xma-133347 Xiphophorus maculatus 51.56 0.00e+00 922.00
IUUC-Yli-134455 Yarrowia lipolytica 51.91 0.00e+00 856.00
IUUC-Zma-135789 Zea mays 47.86 0.00e+00 900.00
Created Date 25-Jun-2017

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