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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063935
Ensembl Protein ID ENSMUSP00000041456.2
UniProt Accession Q91VM3; A2AEV3; A2AEV4; Q9CVF7; Q9JIG9; WIPI4_MOUSE
Genbank Protein ID AAF66949.1; BAB25662.1; BAE26542.1; CAM13587.1; CAM13588.1; AAH11479.1
Protein Name WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain X-linked 1; WD repeat-containing protein 45
Genbank Nucleotide ID AF229635; AK008427; AK145616; AL671995; AL671995; BC011479
Gene Name Wdr45; DXImx38e; Wdrx1; Wipi4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000039382.12 ENSMUST00000208553.1 ENSMUSP00000146660.1
ENSMUSG00000039382.12 ENSMUST00000043045.9 ENSMUSP00000041456.2
ENSMUSG00000039382.12 ENSMUST00000207386.1 ENSMUSP00000146707.1
ENSMUSG00000039382.12 ENSMUST00000116634.8 ENSMUSP00000112333.1
ENSMUSG00000039382.12 ENSMUST00000208524.1 ENSMUSP00000146911.1
ENSMUSG00000039382.12 ENSMUST00000208618.1 ENSMUSP00000146354.1
ENSMUSG00000039382.12 ENSMUST00000208443.1 ENSMUSP00000146886.1
ENSMUSG00000039382.12 ENSMUST00000115688.7 ENSMUSP00000111352.1
ENSMUSG00000039382.12 ENSMUST00000207675.1 ENSMUSP00000147163.1
ENSMUSG00000039382.12 ENSMUST00000116633.8 ENSMUSP00000112332.2
ENSMUSG00000039382.12 ENSMUST00000208996.1 ENSMUSP00000147040.1
ENSMUSG00000039382.12 ENSMUST00000209143.1 ENSMUSP00000147106.1
ENSMUSG00000039382.12 ENSMUST00000207337.1 ENSMUSP00000146506.1
ENSMUSG00000039382.12 ENSMUST00000154253.7 ENSMUSP00000138122.1
ENSMUSG00000039382.12 ENSMUST00000207109.1 ENSMUSP00000147110.1
ENSMUSG00000039382.12 ENSMUST00000208719.1 ENSMUSP00000147254.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.00e-09 39.4 191 223
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgt.ikvWDlr 31
           H+++v c+++  ++t ++s+s  gt i+++D+ 
   Q: 191  HQSDVACVSLnqPGTVVASASQKGTlIRLFDTQ 223
           9*********9877*****************76 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation.
 Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation.
Protein Sequence
(Fasta)
MTQQPLRGVT SLHFNQDQSC FCCAMETGVR IYNVEPLMEK GHLDHEQVGS VGLVEMLHRS 60
NLLALVGGGS SPKFSEISVL IWDDAREGKD SKDKLVLEFT FTKPVLAVRM RHDKIVIVLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063935|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGAGGGCG GCCATCTTGG GACGTTCCAC TTGCTGAAGG GGGCAGAGTG AGGAAGCGGC 60
GCCTGGCCAC GAACGGCCAC CAGTCCGCTC GCCCTAGAAC CCCGTCATGG TATGTCTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063935|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0072--Autophagy
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR032910--WIPI4
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0006914--P:autophagy
KEGG mmu:54636
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001633 Ailuropoda melanoleuca 98.61 0.00e+00 739.00
IUUC-Aca-005110 Anolis carolinensis 93.61 0.00e+00 706.00
IUUC-Bta-013273 Bos taurus 98.61 0.00e+00 739.00
IUUC-Cja-018761 Callithrix jacchus 95.14 0.00e+00 728.00
IUUC-Cfa-020565 Canis familiaris 98.61 0.00e+00 736.00
IUUC-Cpo-021801 Cavia porcellus 98.33 0.00e+00 734.00
IUUC-Csa-023657 Chlorocebus sabaeus 97.78 0.00e+00 736.00
IUUC-Cin-025682 Ciona intestinalis 59.94 1.00e-124 439.00
IUUC-Dre-027718 Danio rerio 89.44 0.00e+00 681.00
IUUC-Dno-029199 Dasypus novemcinctus 98.06 0.00e+00 730.00
IUUC-Dor-030931 Dipodomys ordii 94.28 0.00e+00 693.00
IUUC-Ete-032303 Echinops telfairi 95.71 0.00e+00 639.00
IUUC-Eca-034053 Equus caballus 98.89 0.00e+00 740.00
IUUC-Fca-036502 Felis catus 98.61 0.00e+00 736.00
IUUC-Gmo-038583 Gadus morhua 89.44 0.00e+00 679.00
IUUC-Gac-042546 Gasterosteus aculeatus 89.91 0.00e+00 654.00
IUUC-Ggo-045610 Gorilla gorilla 94.88 0.00e+00 727.00
IUUC-Hsa-046351 Homo sapiens 94.88 0.00e+00 727.00
IUUC-Itr-048533 Ictidomys tridecemlineatus 98.61 0.00e+00 738.00
IUUC-Lch-050439 Latimeria chalumnae 88.83 0.00e+00 672.00
IUUC-Loc-052269 Lepisosteus oculatus 90.00 0.00e+00 682.00
IUUC-Laf-054475 Loxodonta africana 98.33 0.00e+00 736.00
IUUC-Mcc-055829 Macaca mulatta 97.78 0.00e+00 736.00
IUUC-Mmr-061021 Microcebus murinus 93.63 0.00e+00 725.00
IUUC-Mpu-066555 Mustela putorius furo 98.89 0.00e+00 741.00
IUUC-Mlu-067797 Myotis lucifugus 96.94 0.00e+00 723.00
IUUC-Ont-071532 Oreochromis niloticus 90.00 0.00e+00 684.00
IUUC-Ola-086343 Oryzias latipes 88.61 0.00e+00 674.00
IUUC-Oga-088001 Otolemur garnettii 98.89 0.00e+00 740.00
IUUC-Oar-090011 Ovis aries 96.21 0.00e+00 731.00
IUUC-Pan-092470 Papio anubis 97.78 0.00e+00 736.00
IUUC-Pma-094403 Petromyzon marinus 81.23 2.00e-171 594.00
IUUC-Pfo-096982 Poecilia formosa 89.17 0.00e+00 678.00
IUUC-Pca-100176 Procavia capensis 85.44 0.00e+00 630.00
IUUC-Pva-102156 Pteropus vampyrus 95.15 0.00e+00 719.00
IUUC-Rno-105782 Rattus norvegicus 99.44 0.00e+00 744.00
IUUC-Ssc-116318 Sus scrofa 98.61 0.00e+00 739.00
IUUC-Tru-118633 Takifugu rubripes 89.72 0.00e+00 680.00
IUUC-Tsy-119533 Tarsius syrichta 99.03 4.00e-120 423.00
IUUC-Tni-119984 Tetraodon nigroviridis 90.96 0.00e+00 682.00
IUUC-Ttr-128703 Tursiops truncatus 99.07 2.00e-125 442.00
IUUC-Xtr-131754 Xenopus tropicalis 86.39 0.00e+00 625.00
Created Date 25-Jun-2017

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