iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059824

UUCD1 version

UUC-MeG-00249

Ensembl Protein ID

ENSMGAP00000004938.2

UniProt Accession

G1N0I8; G1N0I8_MELGA

Protein Name

Uncharacterized protein

Gene Name

DDB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004990.2	ENSMGAT00000005663.2	ENSMGAP00000004938.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DDB1	0	1670.0	2	1074

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DDB1

   S: 72   nekkdllfilteryntlilelrdidessevvtradgevlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafni 158
           +e+kdllfilt++yn++ile+++ +++++++tra+g+v+D+igr+s++G+i++i+p++r+i+l+ly+glfk+I+ld+++kelkafni
   Q: 2    GESKDLLFILTAKYNACILEYKQNGDNIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRENKELKAFNI 88
           689************************************************************************************ PP
   S: 159  rleelnvsdvkflilltqptgrvlviyqdddgkhlktyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksa 244
           rleel+v+dvkfl+++++pt  ++++yqd++g+h+ktye+sl++KeF+k++ kqe++e+ea+++i+vp++++g++++g+esi+y+++
   Q: 89   RLEELQVIDVKFLYGCQAPT--ICFVYQDPQGRHVKTYEVSLREKEFNKGPwKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNG 173
           ********************..***************************************************************** PP
   S: 245  dnykdvdPylirqstairyervdnngirylLgdfdGelkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfg 330
           d+y +++P++i+qst+++++rvd ng+rylLgd++G+l++lll++ee+m+G v++k+l++elLge+siae+++yldng++fvgsr+g
   Q: 174  DKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGtVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLG 260
           *************************************************************************************** PP
   S: 331  dsQlvklisestgkgsyvvilerfknlkpIvdlvvvdldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkst 417
           dsQlvkl+++s+++gsyvv++e+f+nl+pIvd++vvdl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl++l+s+
   Q: 261  DSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSD 347
           *************************************************************************************** PP
   S: 418  idestdnslvlafvsetkvlnlntgeeledtelsgvlsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigva 504
           + +++dn+lvl+fv++t+vl+ln gee+e+tel+g+++d+qt+++ +v +++ql+q+Ts+svrLvs++ k+l++eWk++n+++i+va
   Q: 348  SHHEMDNMLVLSFVGQTRVLMLN-GEEVEETELTGFVDDQQTFFCGNV-AHQQLIQITSASVRLVSQEPKALVSEWKEPNGKNISVA 432
           ***********************.************************.************************************** PP
   S: 505  ssNteqvliaatsndlvyleigdgeldltstttlenevavldlinieddpnlsdleavglltdiskrililpdletiykeklggeii 591
           s+N++qv++a+ +++l+ylei ++el++++ t++e+eva+ld+++++d++ +s l+a+gl+tdis+ril+lp++e+++ke+lggeii
   Q: 433  SCNSNQVVVAV-GRALYYLEIRPQELRQINCTEMEHEVACLDITPLGDTNGMSPLCAIGLWTDISARILKLPSFEMLHKEMLGGEII 518
           **********9.*************************************************************************** PP
   S: 592  pRsilltefEnvtYlLialgdGalvsyildidtgdesdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlk 678
           pRsil+t+fE+ +YlL+algdGal+++ l  +tg +sd+kk++lgt+p++l+tf+slstt+vfa+sDrPtvIyss++kLvfSnVnlk
   Q: 519  PRSILMTTFESSHYLLCALGDGALFYFGLSLETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLK 605
           *************************************************************************************** PP
   S: 679  eVqylCsldseaypdslalanngslvigtvddiqklkiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilal 764
           eV+y+C+l+s++ypdslalann++l+igt+d+iqkl+iR++pl+es+r+i+yqe++++fgv+s+r+e+++ +++++alr++as++al
   Q: 606  EVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDaSGGTTALRPSASTQAL 692
           **********************************************************************9**************** PP
   S: 765  vpdiennklfsdglrilelseleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgri 851
           +++++ +klfs++++ +e+s++ee+ev++ll++D++tfe+l+a+++ ++E+a+sl+S+kl++D+++y++v+ta+v+pee+e+k+gri
   Q: 693  SSSVSTSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRI 779
           *************************************************************************************** PP
   S: 852  lvfsvedslklkLltvaekkvkgavidlvklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmr 938
           +vf+++d+   kL+  aek+vkgav+++v++Ngklla+ins++rlyew    t ekelr+eC+++n+i+aL+lkt++dfi+VgDlmr
   Q: 780  VVFHYSDG---KLQSLAEKEVKGAVYSMVEFNGKLLASINSTVRLYEW----TAEKELRTECNHYNNIMALYLKTKGDFILVGDLMR 859
           ********...*************************************....*********************************** PP
   S: 939  svtLllykdlegsfeEsardynlewmsaveilnddiflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvl 1025
           sv Ll+yk +eg+feE+ard+n++wmsaveil+dd+flgaen++Nlfv++kd +a++tdeer++l+evg  +lgefv+vf++g+lv+
   Q: 860  SVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKD-SAATTDEERQHLQEVGLSHLGEFVNVFCHGSLVM 945
           ****************************************************.********************************** PP
   S: 1026 qdvgerevnrssevifgtengeigvilrlrrellkflrnlestlkkvikrvakieHs...syRsFetekrterasgfvdgdLiesil 1109
           q++ge++++++++v+fgt+ng+ig++++l+++++++l +++++l+kvik+v+kieHs    +RsF+te++te+a+gf+dgdLies+l
   Q: 946  QNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSlyaTWRSFHTERKTEPATGFIDGDLIESFL 1032
           ********************************************************844469************************* PP
   S: 1110 Dlsrdkavdilkvl.yekrwnskkevsveeivKlveelkrlh 1150
           D+sr+k+++++++l  ++++++k+e++v++++K+veel+r+h
   Q: 1033 DISRPKMQEVVANLqIDDGSGMKREATVDDLIKIVEELTRIH 1074
           **************6699**********************98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QGESKDLLFI LTAKYNACIL EYKQNGDNID IITRAHGNVQ DRIGRPSETG IIGIIDPECR 60
MIGLRLYDGL FKVIPLDREN KELKAFNIRL EELQVIDVKF LYGCQAPTIC FVYQDPQGRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGGAGA GCAAGGATCT ACTTTTCATC CTGACAGCCA AGTACAACGC GTGCATCCTG 60
GAGTACAAGC AGAATGGTGA CAATATTGAC ATTATCACCC GTGCCCATGG AAATGTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom

Pfam

PF03178--CPSF_A

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:0051702--P:interaction with symbiont
GO:0043066--P:negative regulation of apoptotic process
GO:0046726--P:positive regulation by virus of viral protein levels in host cell
GO:0045070--P:positive regulation of viral genome replication
GO:1902188--P:positive regulation of viral release from host cell
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901990--P:regulation of mitotic cell cycle phase transition
GO:0070914--P:UV-damage excision repair
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000120	Aegilops tauschii	49.56	0.00e+00	1046.00
IUUC-Aml-002096	Ailuropoda melanoleuca	96.46	0.00e+00	2104.00
IUUC-Atr-002742	Amborella trichopoda	51.76	0.00e+00	1096.00
IUUC-Apl-003624	Anas platyrhynchos	99.07	0.00e+00	2156.00
IUUC-Aca-005085	Anolis carolinensis	96.55	0.00e+00	2109.00
IUUC-Aly-005857	Arabidopsis lyrata	52.36	0.00e+00	1097.00
IUUC-Ath-006658	Arabidopsis thaliana	52.17	0.00e+00	1093.00
IUUC-Acl-008149	Aspergillus clavatus	26.74	1.00e-94	341.00
IUUC-Afl-008549	Aspergillus flavus	27.73	8.00e-102	364.00
IUUC-Afu-009076	Aspergillus fumigatus	26.94	4.00e-105	375.00
IUUC-Ani-009302	Aspergillus nidulans	26.82	9.00e-80	291.00
IUUC-Ang-009636	Aspergillus niger	27.95	2.00e-81	297.00
IUUC-Aor-010073	Aspergillus oryzae	27.73	6.00e-102	365.00
IUUC-Ate-010422	Aspergillus terreus	27.11	2.00e-95	343.00
IUUC-Ame-011643	Astyanax mexicanus	79.89	0.00e+00	1709.00
IUUC-Bgr-012164	Blumeria graminis	26.10	2.00e-87	317.00
IUUC-Bta-012494	Bos taurus	96.46	0.00e+00	2105.00
IUUC-Bci-013957	Botrytis cinerea	26.13	2.00e-80	293.00
IUUC-Bdi-014186	Brachypodium distachyon	52.27	0.00e+00	1092.00
IUUC-Bol-015922	Brassica oleracea	52.64	0.00e+00	1107.00
IUUC-Bra-017300	Brassica rapa	52.64	0.00e+00	1101.00
IUUC-Cel-018239	Caenorhabditis elegans	37.50	0.00e+00	733.00
IUUC-Cja-019165	Callithrix jacchus	96.37	0.00e+00	2102.00
IUUC-Cfa-020406	Canis familiaris	96.46	0.00e+00	2104.00
IUUC-Cpo-022154	Cavia porcellus	95.81	0.00e+00	2088.00
IUUC-Cre-022557	Chlamydomonas reinhardtii	40.34	0.00e+00	715.00
IUUC-Csa-024061	Chlorocebus sabaeus	96.37	0.00e+00	2102.00
IUUC-Cho-024554	Choloepus hoffmanni	90.40	0.00e+00	921.00
IUUC-Cin-025466	Ciona intestinalis	61.14	0.00e+00	1367.00
IUUC-Csv-026370	Ciona savignyi	60.24	0.00e+00	1311.00
IUUC-Cgl-026595	Colletotrichum gloeosporioides	26.33	9.00e-88	318.00
IUUC-Cme-027342	Cyanidioschyzon merolae	27.62	3.00e-116	412.00
IUUC-Dre-027448	Danio rerio	91.23	0.00e+00	1026.00
IUUC-Dno-029794	Dasypus novemcinctus	96.06	0.00e+00	1976.00
IUUC-Dor-030789	Dipodomys ordii	83.09	0.00e+00	965.00
IUUC-Dse-031491	Dothistroma septosporum	27.84	1.00e-107	384.00
IUUC-Dme-031940	Drosophila melanogaster	60.95	0.00e+00	1279.00
IUUC-Ete-032913	Echinops telfairi	78.85	0.00e+00	845.00
IUUC-Eca-033777	Equus caballus	95.81	0.00e+00	2081.00
IUUC-Eeu-034900	Erinaceus europaeus	94.61	0.00e+00	1098.00
IUUC-Fca-035869	Felis catus	96.46	0.00e+00	2104.00
IUUC-Fal-036777	Ficedula albicollis	98.98	0.00e+00	2156.00
IUUC-Fox-037954	Fusarium oxysporum	26.47	4.00e-92	332.00
IUUC-Fso-038292	Fusarium solani	25.70	4.00e-97	349.00
IUUC-Gmo-038815	Gadus morhua	82.00	0.00e+00	968.00
IUUC-Ggr-039907	Gaeumannomyces graminis	26.27	2.00e-90	327.00
IUUC-Gga-040995	Gallus gallus	99.35	0.00e+00	2158.00
IUUC-Gac-042390	Gasterosteus aculeatus	89.17	0.00e+00	1850.00
IUUC-Gma-042904	Glycine max	51.62	0.00e+00	1051.00
IUUC-Ggo-044891	Gorilla gorilla	96.46	0.00e+00	2107.00
IUUC-Hsa-046709	Homo sapiens	96.37	0.00e+00	2102.00
IUUC-Hvu-047504	Hordeum vulgare	51.90	0.00e+00	1072.00
IUUC-Itr-048678	Ictidomys tridecemlineatus	96.37	0.00e+00	2104.00
IUUC-Lch-050565	Latimeria chalumnae	93.85	0.00e+00	2063.00
IUUC-Lpe-051260	Leersia perrieri	52.36	0.00e+00	1090.00
IUUC-Loc-052091	Lepisosteus oculatus	82.49	0.00e+00	1490.00
IUUC-Lma-053246	Leptosphaeria maculans	25.13	2.00e-99	356.00
IUUC-Laf-053502	Loxodonta africana	96.18	0.00e+00	2100.00
IUUC-Mcc-054802	Macaca mulatta	96.43	0.00e+00	2085.00
IUUC-Meu-056808	Macropus eugenii	94.16	0.00e+00	1334.00
IUUC-Mor-057253	Magnaporthe oryzae	25.48	6.00e-71	262.00
IUUC-Mpo-057562	Magnaporthe poae	26.02	1.00e-86	314.00
IUUC-Mtr-057743	Medicago truncatula	51.06	0.00e+00	1070.00
IUUC-Mla-059154	Melampsora laricipopulina	25.05	1.00e-69	258.00
IUUC-Mvi-060279	Microbotryum violaceum	27.60	4.00e-106	379.00
IUUC-Mmr-061215	Microcebus murinus	96.00	0.00e+00	2087.00
IUUC-Mdo-062028	Monodelphis domestica	95.67	0.00e+00	1865.00
IUUC-Mmu-064327	Mus musculus	96.37	0.00e+00	2101.00
IUUC-Mac-065445	Musa acuminata	52.35	0.00e+00	1070.00
IUUC-Mpu-065814	Mustela putorius furo	93.11	0.00e+00	2008.00
IUUC-Mlu-067136	Myotis lucifugus	96.37	0.00e+00	2097.00
IUUC-Nfi-068355	Neosartorya fischeri	26.94	7.00e-99	355.00
IUUC-Ncr-068620	Neurospora crassa	25.24	5.00e-80	292.00
IUUC-Nle-069566	Nomascus leucogenys	96.24	0.00e+00	2071.00
IUUC-Opr-070915	Ochotona princeps	88.78	0.00e+00	1831.00
IUUC-Ont-071753	Oreochromis niloticus	90.32	0.00e+00	1969.00
IUUC-Oan-073187	Ornithorhynchus anatinus	96.81	0.00e+00	2031.00
IUUC-Ocu-074619	Oryctolagus cuniculus	96.55	0.00e+00	2106.00
IUUC-Oba-075091	Oryza barthii	44.30	0.00e+00	859.00
IUUC-Obr-076425	Oryza brachyantha	52.76	0.00e+00	1094.00
IUUC-Ogu-078794	Oryza glumaepatula	52.54	0.00e+00	1096.00
IUUC-Oin-079725	Oryza indica	52.45	0.00e+00	1082.00
IUUC-Olo-080842	Oryza longistaminata	50.76	0.00e+00	1072.00
IUUC-Ome-081818	Oryza meridionalis	52.64	0.00e+00	1099.00
IUUC-Oni-082879	Oryza nivara	51.80	0.00e+00	1073.00
IUUC-Opu-083361	Oryza punctata	51.92	0.00e+00	1088.00
IUUC-Oru-084781	Oryza rufipogon	52.54	0.00e+00	1097.00
IUUC-Osa-086293	Oryza sativa	52.54	0.00e+00	1097.00
IUUC-Ola-086881	Oryzias latipes	90.05	0.00e+00	1965.00
IUUC-Olu-087674	Ostreococcus lucimarinus	44.95	0.00e+00	887.00
IUUC-Oga-089056	Otolemur garnettii	96.37	0.00e+00	2101.00
IUUC-Oar-089457	Ovis aries	96.59	0.00e+00	2070.00
IUUC-Ptr-091179	Pan troglodytes	96.37	0.00e+00	2101.00
IUUC-Pan-092019	Papio anubis	96.28	0.00e+00	2101.00
IUUC-Psi-093407	Pelodiscus sinensis	97.12	0.00e+00	2118.00
IUUC-Pma-094272	Petromyzon marinus	86.48	0.00e+00	1758.00
IUUC-Pno-094864	Phaeosphaeria nodorum	25.89	2.00e-101	363.00
IUUC-Ppa-095885	Physcomitrella patens	52.72	0.00e+00	1076.00
IUUC-Pfo-096083	Poecilia formosa	89.94	0.00e+00	1964.00
IUUC-Pab-098652	Pongo abelii	91.66	0.00e+00	1974.00
IUUC-Pop-099593	Populus trichocarpa	52.36	0.00e+00	1048.00
IUUC-Pca-100189	Procavia capensis	96.14	0.00e+00	1290.00
IUUC-Ppe-101987	Prunus persica	51.90	0.00e+00	1048.00
IUUC-Pva-102605	Pteropus vampyrus	96.28	0.00e+00	2098.00
IUUC-Pgr-103659	Puccinia graminis	25.17	3.00e-60	227.00
IUUC-Ptt-103884	Puccinia triticina	24.36	2.00e-52	201.00
IUUC-Pte-104233	Pyrenophora teres	26.20	6.00e-101	362.00
IUUC-Pyt-104454	Pyrenophora triticirepentis	26.46	2.00e-99	356.00
IUUC-Rno-106004	Rattus norvegicus	96.37	0.00e+00	2102.00
IUUC-Sha-106726	Sarcophilus harrisii	95.06	0.00e+00	2048.00
IUUC-Sja-107864	Schizosaccharomyces japonicus	24.55	2.00e-69	257.00
IUUC-Spo-108029	Schizosaccharomyces pombe	26.75	3.00e-90	326.00
IUUC-Ssl-108441	Sclerotinia sclerotiorum	25.13	2.00e-71	263.00
IUUC-Smo-108808	Selaginella moellendorffii	52.18	0.00e+00	1126.00
IUUC-Sit-109735	Setaria italica	52.57	0.00e+00	1086.00
IUUC-Sly-111520	Solanum lycopersicum	52.22	0.00e+00	1077.00
IUUC-Sar-113606	Sorex araneus	92.12	3.00e-130	459.00
IUUC-Sbi-114539	Sorghum bicolor	51.56	0.00e+00	1075.00
IUUC-Sre-114936	Sporisorium reilianum	25.67	1.00e-63	238.00
IUUC-Ssc-116038	Sus scrofa	96.46	0.00e+00	2103.00
IUUC-Tgu-117512	Taeniopygia guttata	98.14	0.00e+00	2132.00
IUUC-Tru-117593	Takifugu rubripes	88.74	0.00e+00	1941.00
IUUC-Tsy-119513	Tarsius syrichta	93.21	0.00e+00	1171.00
IUUC-Tni-120551	Tetraodon nigroviridis	84.68	0.00e+00	1695.00
IUUC-Tca-121505	Theobroma cacao	52.54	0.00e+00	1070.00
IUUC-Tre-122136	Trichoderma reesei	25.95	3.00e-92	333.00
IUUC-Tvi-122512	Trichoderma virens	24.72	4.00e-88	319.00
IUUC-Tae-124186	Triticum aestivum	51.80	0.00e+00	1071.00
IUUC-Tur-126451	Triticum urartu	52.43	0.00e+00	1046.00
IUUC-Tme-127057	Tuber melanosporum	29.70	9.00e-102	364.00
IUUC-Ttr-128891	Tursiops truncatus	91.29	0.00e+00	1434.00
IUUC-Uma-129583	Ustilago maydis	25.64	8.00e-55	209.00
IUUC-Vda-129870	Verticillium dahliae	25.60	2.00e-84	306.00
IUUC-Vpa-130117	Vicugna pacos	92.00	0.00e+00	1605.00
IUUC-Vvi-131033	Vitis vinifera	51.53	0.00e+00	1074.00
IUUC-Xtr-131987	Xenopus tropicalis	91.74	0.00e+00	1987.00
IUUC-Xma-134117	Xiphophorus maculatus	89.76	0.00e+00	1956.00
IUUC-Zma-134758	Zea mays	52.54	0.00e+00	1093.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence