iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011206

Ensembl Protein ID

ENSAMXP00000010303.1

UniProt Accession

W5KRU1; W5KRU1_ASTMX

Genbank Protein ID

ENSAMXP00000010303

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01102876

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010037.1	ENSAMXT00000010303.1	ENSAMXP00000010303.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-76	257.7	190	561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 190  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 272
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +s r ++ ld++l ++ 
   Q: 273  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINQLYQGKLKDYVRCLECGYESWRIDTYLDIPLVIRP 335
           ******************..........................678999*************************************95 PP
   S: 179  kee.tkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
               ++  s++++L++f ++e+l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+spf  
   Q: 336  FGAsQAFGSVEEALQAFIQPETLDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSPFID 424
           44304567*******************************************************************************99 PP
   S: 267  speekqke..................................................kkkYeLiavvvHsGslssGHYvayvkn.ekg 304
            ++ek+ +                                                  + ++eL++v+vHsGs+ +GHY+a++k+ ++g
   Q: 425  LEDEKSPQtesctdsgaenegschsdqmsndfstddgvdegicldstsatervlkpksSLTFELFSVMVHSGSAAGGHYYACIKSfSDG 513
           9777776688999999999999999999999999999999999999999999***999***************************6677 PP
   S: 305  kWllfdDskVtevkeeevleetg................staYvlfYk 336
           +W+ f+D++V++++++++ ++ g                ++aY+l+Y+
   Q: 514  QWYSFNDQHVSKITQDDIRKTYGgssgsrgyyssafassTNAYMLIYR 561
           7*******************888************************8 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MFFSVLSSVL CHQGVFWSCR QSIFEEMKKK FSQIESAAEE PRVLCIVQDT TNAKTVNERL 60
TLNLPASTSV AKLYEDVAQK AGYVNGTFEL GWGNVVDMAP LDQASEMSLV ESGFEAGKRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTTTTTCT CATCTTCTAT TGTTTAAATG GTAACCATGC CTGCCTTAAA GTTCTGTCAG 60
TAGTCAGAAA GTCTAAGTAA ACCAAACTGC ACCAAGCAAA CTGCACTGTG ACGTAACCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004088--KH_dom_type_1
IPR001394--Peptidase_C19_UCH
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF14560--Ubiquitin_2
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	79.67	0.00e+00	2081.00
IUUC-Apl-003486	Anas platyrhynchos	80.64	0.00e+00	2075.00
IUUC-Aca-005061	Anolis carolinensis	80.59	0.00e+00	2136.00
IUUC-Bta-012942	Bos taurus	79.91	0.00e+00	2088.00
IUUC-Cel-018600	Caenorhabditis elegans	38.25	2.00e-122	433.00
IUUC-Cja-018950	Callithrix jacchus	80.57	0.00e+00	1955.00
IUUC-Cfa-020299	Canis familiaris	80.54	0.00e+00	2095.00
IUUC-Cpo-021943	Cavia porcellus	80.64	0.00e+00	2102.00
IUUC-Csa-023285	Chlorocebus sabaeus	80.23	0.00e+00	2056.00
IUUC-Cho-025006	Choloepus hoffmanni	74.21	0.00e+00	1815.00
IUUC-Cin-025145	Ciona intestinalis	48.24	1.00e-163	570.00
IUUC-Csv-025839	Ciona savignyi	49.54	1.00e-160	561.00
IUUC-Dre-027959	Danio rerio	92.14	0.00e+00	2327.00
IUUC-Dno-030023	Dasypus novemcinctus	77.72	0.00e+00	2007.00
IUUC-Dor-030994	Dipodomys ordii	75.18	0.00e+00	738.00
IUUC-Dme-031604	Drosophila melanogaster	50.00	1.00e-146	514.00
IUUC-Ete-032596	Echinops telfairi	65.20	0.00e+00	1022.00
IUUC-Eca-033913	Equus caballus	80.14	0.00e+00	2089.00
IUUC-Eeu-034518	Erinaceus europaeus	74.56	0.00e+00	1763.00
IUUC-Fca-035997	Felis catus	80.36	0.00e+00	2112.00
IUUC-Fal-037088	Ficedula albicollis	81.49	0.00e+00	1851.00
IUUC-Gmo-038920	Gadus morhua	84.75	0.00e+00	2168.00
IUUC-Gga-040953	Gallus gallus	80.16	0.00e+00	2055.00
IUUC-Gac-042400	Gasterosteus aculeatus	85.36	0.00e+00	2161.00
IUUC-Ggo-044820	Gorilla gorilla	78.58	0.00e+00	2026.00
IUUC-Hsa-046634	Homo sapiens	80.01	0.00e+00	2083.00
IUUC-Lch-050440	Latimeria chalumnae	82.34	0.00e+00	2185.00
IUUC-Loc-051904	Lepisosteus oculatus	87.44	0.00e+00	2282.00
IUUC-Laf-053760	Loxodonta africana	79.65	0.00e+00	2106.00
IUUC-Mcc-054637	Macaca mulatta	80.16	0.00e+00	2089.00
IUUC-Meu-056904	Macropus eugenii	81.03	0.00e+00	1415.00
IUUC-Mga-059556	Meleagris gallopavo	79.91	0.00e+00	2045.00
IUUC-Mmr-061192	Microcebus murinus	80.52	0.00e+00	2101.00
IUUC-Mdo-061929	Monodelphis domestica	81.31	0.00e+00	2121.00
IUUC-Mmu-063726	Mus musculus	79.37	0.00e+00	2103.00
IUUC-Mpu-066014	Mustela putorius furo	80.76	0.00e+00	2087.00
IUUC-Mlu-067232	Myotis lucifugus	79.70	0.00e+00	2080.00
IUUC-Nle-069619	Nomascus leucogenys	80.09	0.00e+00	2053.00
IUUC-Opr-070224	Ochotona princeps	77.44	0.00e+00	937.00
IUUC-Ont-071384	Oreochromis niloticus	87.90	0.00e+00	2223.00
IUUC-Oan-073208	Ornithorhynchus anatinus	79.39	0.00e+00	2093.00
IUUC-Ocu-074285	Oryctolagus cuniculus	80.23	0.00e+00	2097.00
IUUC-Ola-087051	Oryzias latipes	86.64	0.00e+00	2151.00
IUUC-Oga-088928	Otolemur garnettii	80.42	0.00e+00	2102.00
IUUC-Oar-090215	Ovis aries	80.17	0.00e+00	2090.00
IUUC-Ptr-091035	Pan troglodytes	80.09	0.00e+00	2087.00
IUUC-Pan-092377	Papio anubis	79.77	0.00e+00	2067.00
IUUC-Pfo-096722	Poecilia formosa	86.64	0.00e+00	2206.00
IUUC-Pab-098723	Pongo abelii	80.09	0.00e+00	2088.00
IUUC-Pca-100105	Procavia capensis	75.77	0.00e+00	1912.00
IUUC-Pva-102514	Pteropus vampyrus	85.12	0.00e+00	831.00
IUUC-Rno-105384	Rattus norvegicus	79.18	0.00e+00	2069.00
IUUC-Sha-106982	Sarcophilus harrisii	80.31	0.00e+00	2100.00
IUUC-Sar-113723	Sorex araneus	76.81	0.00e+00	835.00
IUUC-Ssc-115671	Sus scrofa	79.95	0.00e+00	1651.00
IUUC-Tgu-116722	Taeniopygia guttata	80.13	0.00e+00	2035.00
IUUC-Tru-118380	Takifugu rubripes	86.17	0.00e+00	2180.00
IUUC-Tsy-119646	Tarsius syrichta	74.93	0.00e+00	1899.00
IUUC-Tni-120762	Tetraodon nigroviridis	85.89	0.00e+00	2203.00
IUUC-Tbe-127861	Tupaia belangeri	78.88	0.00e+00	1938.00
IUUC-Ttr-129254	Tursiops truncatus	74.03	0.00e+00	1149.00
IUUC-Vpa-130141	Vicugna pacos	84.86	0.00e+00	1033.00
IUUC-Xtr-132700	Xenopus tropicalis	78.24	0.00e+00	2082.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence