iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036232

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02048431

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013194.3	ENSFCAT00000013198.3	ENSFCAP00000012237.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-28	96.7	333	368
UBD/Beta-Prp	5.60e-46	157.1	331	616

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D  i++W++  g+l
   Q: 333  HLSEVNAVCFgPNsSLLATGGADRFIHLWNVVGGRL 368
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+ ++ +   +++++w +   +   tl+gh
   Q: 331  NAHLSEVNAVCFGPNSSLLATGGADRFIHLWNVVGGRLeaNQTLEGAGGSITSVDFDPSGSQILAATYNQAAQLWKVGEAQSKETLSGH 419
           57889999******************************88899******************99999999******************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 420  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHVIISGHNDQKIRFWDSRGPCCTQVIP--VQGR 502
           ************************************9.666665...4555555556****************9999999995..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sl++++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg +++Wd+++g+l ++l +++ +
   Q: 503  VTSLNLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSWDGALYVWDVDTGKLEGSLRGPHCT 590
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 591  AVNAVAWCYSGSHVVSVDQARKVVLW 616
           7777778************9999999 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MEGPGAPGVP WKRHIVRQLR QRDRTQKALF LELVPAYNHL LEKAELLARI SEKLQPEPND 60
ATPAMHQGPW EEELEPDSDQ VPSPTTLRMK WQEEEEGLRL VCGEMAYQVV EKSAALGALE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGGC CCGGCGCCCC CGGTGTCCCC TGGAAACGCC ACATAGTGCG GCAGCTTCGG 60
CAGCGGGACC GCACGCAAAA GGCACTCTTC CTGGAACTGG TGCCTGCCTG TGAGTGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005654--C:nucleoplasm
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

fca:101083109

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	72.45	0.00e+00	841.00
IUUC-Atr-003073	Amborella trichopoda	32.09	4.00e-27	115.00
IUUC-Aca-004664	Anolis carolinensis	66.67	8.00e-100	355.00
IUUC-Ame-011152	Astyanax mexicanus	43.91	4.00e-121	428.00
IUUC-Bta-013118	Bos taurus	85.32	0.00e+00	962.00
IUUC-Cja-020002	Callithrix jacchus	84.42	0.00e+00	936.00
IUUC-Cfa-020878	Canis familiaris	88.94	0.00e+00	1021.00
IUUC-Cpo-022476	Cavia porcellus	82.54	0.00e+00	926.00
IUUC-Csa-024134	Chlorocebus sabaeus	84.89	0.00e+00	944.00
IUUC-Cho-024853	Choloepus hoffmanni	69.26	2.00e-180	625.00
IUUC-Dre-027949	Danio rerio	41.49	1.00e-131	463.00
IUUC-Dno-029683	Dasypus novemcinctus	84.12	0.00e+00	800.00
IUUC-Dor-030897	Dipodomys ordii	77.98	0.00e+00	914.00
IUUC-Ete-032957	Echinops telfairi	94.02	6.00e-133	468.00
IUUC-Eca-033303	Equus caballus	91.05	3.00e-167	580.00
IUUC-Eeu-035336	Erinaceus europaeus	74.69	3.00e-156	545.00
IUUC-Ggo-045130	Gorilla gorilla	89.33	0.00e+00	690.00
IUUC-Hsa-046359	Homo sapiens	86.49	0.00e+00	922.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	83.63	0.00e+00	945.00
IUUC-Lch-050669	Latimeria chalumnae	53.92	6.00e-94	337.00
IUUC-Loc-052789	Lepisosteus oculatus	42.22	7.00e-120	424.00
IUUC-Laf-053699	Loxodonta africana	84.55	0.00e+00	934.00
IUUC-Mcc-055657	Macaca mulatta	80.48	0.00e+00	850.00
IUUC-Meu-056639	Macropus eugenii	49.22	6.00e-115	407.00
IUUC-Mmr-061314	Microcebus murinus	78.19	0.00e+00	853.00
IUUC-Mdo-061841	Monodelphis domestica	64.66	0.00e+00	717.00
IUUC-Mmu-064065	Mus musculus	82.40	0.00e+00	954.00
IUUC-Mpu-066742	Mustela putorius furo	88.85	0.00e+00	988.00
IUUC-Mlu-067019	Myotis lucifugus	86.68	0.00e+00	840.00
IUUC-Nle-069037	Nomascus leucogenys	86.49	0.00e+00	965.00
IUUC-Opr-071039	Ochotona princeps	79.48	0.00e+00	894.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.91	1.00e-137	482.00
IUUC-Ocu-074772	Oryctolagus cuniculus	84.10	0.00e+00	838.00
IUUC-Ola-086964	Oryzias latipes	52.80	3.00e-82	297.00
IUUC-Oga-088188	Otolemur garnettii	82.88	0.00e+00	909.00
IUUC-Oar-090231	Ovis aries	79.77	0.00e+00	946.00
IUUC-Ptr-091434	Pan troglodytes	84.05	0.00e+00	880.00
IUUC-Pan-091868	Papio anubis	85.81	0.00e+00	940.00
IUUC-Psi-093652	Pelodiscus sinensis	64.80	7.00e-165	573.00
IUUC-Pfo-096960	Poecilia formosa	41.75	4.00e-102	365.00
IUUC-Pab-097776	Pongo abelii	85.83	0.00e+00	879.00
IUUC-Pca-100220	Procavia capensis	64.83	2.00e-178	618.00
IUUC-Pva-103135	Pteropus vampyrus	88.46	0.00e+00	899.00
IUUC-Rno-105529	Rattus norvegicus	81.12	0.00e+00	975.00
IUUC-Sha-107062	Sarcophilus harrisii	64.75	0.00e+00	746.00
IUUC-Sar-113109	Sorex araneus	66.51	3.00e-137	481.00
IUUC-Ssc-115271	Sus scrofa	86.63	0.00e+00	936.00
IUUC-Ttr-128267	Tursiops truncatus	88.22	0.00e+00	718.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence