iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000039328.11	ENSMUST00000046941.7	ENSMUSP00000040478.7
ENSMUSG00000039328.11	ENSMUST00000217278.1	ENSMUSP00000150893.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.20e-08	34.2	93	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cledf  kd++ vlpC+H+fh++Cl kw         +  CP C+
   Q: 93   CAVCLEDFkgKDELGVLPCQHAFHRKCLVKW------LEVRCVCPMCN 134
           ********99778******************......999999****7 PP

Organism

Mus musculus

Functional Description
(View)

May induce necrosis and apoptosis. May play a role in cell viability (By similarity).

Protein Sequence
(Fasta)

MHPFQWCNGC FCGLGLVSTN KSCSMPPISF QDLPLNIYMV IFGTGIFVFM LSLIFCCYFI 60
SKLRNQAQSE RYGYKEVVLK GDAKKLQLYG QTCAVCLEDF KGKDELGVLP CQHAFHRKCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCGGTGTC AGTTTTCGGA ATCCCAGCGC GCACTGCTCA GCGCAGTGGG ACCCAAGCCC 60
GGCTTCGTGT CCTGGCTACT GCCTTCTCGG CCGGGCATCC CGGCTCTCTC GGCTGCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mmu:68867

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002066	Ailuropoda melanoleuca	97.42	5.00e-88	315.00
IUUC-Apl-003691	Anas platyrhynchos	84.21	2.00e-65	241.00
IUUC-Aca-004989	Anolis carolinensis	89.68	2.00e-82	297.00
IUUC-Ame-011731	Astyanax mexicanus	83.23	1.00e-77	281.00
IUUC-Bta-012760	Bos taurus	97.28	2.00e-80	290.00
IUUC-Cja-019442	Callithrix jacchus	96.77	1.00e-87	315.00
IUUC-Cfa-021257	Canis familiaris	93.55	1.00e-82	298.00
IUUC-Cpo-021821	Cavia porcellus	91.14	1.00e-81	294.00
IUUC-Csa-023926	Chlorocebus sabaeus	96.77	1.00e-87	314.00
IUUC-Cho-024763	Choloepus hoffmanni	92.55	2.00e-49	186.00
IUUC-Cme-027308	Cyanidioschyzon merolae	36.00	7.00e-09	56.20
IUUC-Dre-028547	Danio rerio	83.23	1.00e-77	281.00
IUUC-Dno-029352	Dasypus novemcinctus	96.77	2.00e-87	313.00
IUUC-Dor-030113	Dipodomys ordii	97.87	3.00e-51	192.00
IUUC-Ete-032590	Echinops telfairi	83.23	5.00e-74	269.00
IUUC-Eca-033808	Equus caballus	97.42	3.00e-88	316.00
IUUC-Eeu-035101	Erinaceus europaeus	95.89	1.00e-79	288.00
IUUC-Fca-035925	Felis catus	98.06	3.00e-88	317.00
IUUC-Gmo-038545	Gadus morhua	89.03	3.00e-80	290.00
IUUC-Gga-041003	Gallus gallus	81.29	9.00e-74	268.00
IUUC-Gac-042633	Gasterosteus aculeatus	62.04	3.00e-41	160.00
IUUC-Hsa-047006	Homo sapiens	96.77	2.00e-87	313.00
IUUC-Itr-048723	Ictidomys tridecemlineatus	96.13	9.00e-86	308.00
IUUC-Loc-052517	Lepisosteus oculatus	90.48	1.00e-75	274.00
IUUC-Laf-053986	Loxodonta africana	96.13	2.00e-85	307.00
IUUC-Mcc-054860	Macaca mulatta	94.70	5.00e-81	292.00
IUUC-Meu-056640	Macropus eugenii	80.56	3.00e-61	226.00
IUUC-Mla-059067	Melampsora laricipopulina	39.53	3.00e-08	54.30
IUUC-Mmr-061260	Microcebus murinus	96.53	8.00e-78	282.00
IUUC-Mdo-062793	Monodelphis domestica	90.48	1.00e-76	277.00
IUUC-Mpu-066068	Mustela putorius furo	98.06	3.00e-88	317.00
IUUC-Mlu-067176	Myotis lucifugus	97.42	1.00e-87	314.00
IUUC-Nle-069924	Nomascus leucogenys	95.48	3.00e-86	310.00
IUUC-Opr-070985	Ochotona princeps	96.77	1.00e-85	308.00
IUUC-Ont-071718	Oreochromis niloticus	63.50	6.00e-43	166.00
IUUC-Oan-073727	Ornithorhynchus anatinus	90.41	2.00e-76	277.00
IUUC-Ocu-074776	Oryctolagus cuniculus	96.71	2.00e-84	303.00
IUUC-Obr-076171	Oryza brachyantha	44.26	4.00e-12	64.70
IUUC-Ome-081724	Oryza meridionalis	46.15	2.00e-11	64.30
IUUC-Oru-084685	Oryza rufipogon	52.27	2.00e-11	62.00
IUUC-Ola-087147	Oryzias latipes	88.39	3.00e-80	290.00
IUUC-Oga-087917	Otolemur garnettii	98.71	1.00e-88	318.00
IUUC-Oar-089739	Ovis aries	94.81	2.00e-83	300.00
IUUC-Ptr-090619	Pan troglodytes	96.77	2.00e-87	313.00
IUUC-Pan-092854	Papio anubis	96.77	1.00e-87	314.00
IUUC-Psi-093254	Pelodiscus sinensis	91.20	3.00e-66	244.00
IUUC-Pma-094708	Petromyzon marinus	67.11	2.00e-24	103.00
IUUC-Pfo-096899	Poecilia formosa	88.39	5.00e-80	289.00
IUUC-Pab-097858	Pongo abelii	97.42	7.00e-88	315.00
IUUC-Pca-100210	Procavia capensis	96.77	3.00e-87	313.00
IUUC-Pva-102677	Pteropus vampyrus	96.13	2.00e-85	307.00
IUUC-Rno-105488	Rattus norvegicus	85.50	6.00e-60	222.00
IUUC-Sha-107332	Sarcophilus harrisii	90.54	3.00e-77	280.00
IUUC-Sar-113175	Sorex araneus	94.44	6.00e-57	211.00
IUUC-Ssc-115896	Sus scrofa	97.42	3.00e-86	310.00
IUUC-Tru-118255	Takifugu rubripes	80.00	7.00e-69	252.00
IUUC-Tsy-119575	Tarsius syrichta	97.42	4.00e-88	316.00
IUUC-Tni-120329	Tetraodon nigroviridis	77.42	2.00e-66	244.00
IUUC-Ttr-128649	Tursiops truncatus	97.42	1.00e-87	314.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence