iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093691

Ensembl Protein ID

ENSPSIP00000011576.1

UniProt Accession

K7FU66; K7FU66_PELSI

Genbank Protein ID

ENSPSIP00000011576

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01091441

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010460.1	ENSPSIT00000011633.1	ENSPSIP00000011576.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-77	260.8	42	493

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G+kN+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++ ++       +  +lq+lf++l+  +++a s+++l++++++ ++e  +
   Q: 42   GIKNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEDINKPDvkvrIIPLQLQRLFAQLLLLDQQAASTTDLTESFGWNSNE--E 128
           9*****************************777777766542222234448899***************************99998..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+r+e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTVVNQIVCKECKNVSERQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+++L +++++ee +e++n y c  c+k++ea k+ kl+klP++L++ L Rf+f+ e++ r k  ++++fp++++l+p
   Q: 192  VKDVS-----GLEEALwNMYVEEEYFENDNLYRCGACNKLVEAAKSAKLRKLPPFLTVSLLRFNFDFEKCERYKEMSCYTFPIRINLRP 275
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++  ++ ++++YeL++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQTHLDD-SEYIYELFSVIIHKGGCYGGHYHVYIKDvdalgnwqlkeeesklmskekdqketenvkemenpltvlkeilseeeskqi 363
           ****88877.59***************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 364  pvdqlgqkllekkgvswnkkyrkqygpirkylqnhsqifllspdenkvslkemyhklqfgsdsqgqglqspsqdsdvqwtseslctvlk 452
           **********************************************************************9999999999999999987 PP
   S: 302  ...ekgk..WllfdDskVtevkeeevleetg..staYvlfYkr 337
              +  +  W+ ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 453  dntS--GshWFDLNDSKVQPIKEKDIEKQFQgkESAYMLFYRK 493
           6533..157*******************9889*********98 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MFGDLFEEDF SFVSNNQCGK GKKSKSKDTE TPAPREFTNL SGIKNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGSL EDINKPDVKV RIIPLQLQRL FAQLLLLDQQ AASTTDLTES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACATGTAA AAATTTTCGA TGATATGAAA CTGAAAATGG TTGCAGGTAT ATTGGAGAAC 60
AGTATTAGGG TGCCCAACCC GCCTGAGCTC GGGCAGCCCC GGGAGCCGAG ACCCACCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pss:102447001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	66.53	0.00e+00	1498.00
IUUC-Apl-004105	Anas platyrhynchos	79.74	0.00e+00	1988.00
IUUC-Aca-004715	Anolis carolinensis	72.00	0.00e+00	1767.00
IUUC-Ame-011073	Astyanax mexicanus	48.08	0.00e+00	1058.00
IUUC-Bta-012487	Bos taurus	64.80	0.00e+00	1534.00
IUUC-Cja-018937	Callithrix jacchus	66.05	0.00e+00	1583.00
IUUC-Cfa-020645	Canis familiaris	59.67	0.00e+00	919.00
IUUC-Cpo-022160	Cavia porcellus	64.57	0.00e+00	1533.00
IUUC-Csa-023078	Chlorocebus sabaeus	66.45	0.00e+00	1612.00
IUUC-Cho-025013	Choloepus hoffmanni	51.73	2.00e-174	605.00
IUUC-Cin-025145	Ciona intestinalis	40.76	2.00e-42	167.00
IUUC-Csv-026193	Ciona savignyi	55.84	3.00e-59	221.00
IUUC-Dre-027416	Danio rerio	50.47	0.00e+00	1155.00
IUUC-Dno-029639	Dasypus novemcinctus	62.24	0.00e+00	1274.00
IUUC-Dor-030624	Dipodomys ordii	77.96	2.00e-132	466.00
IUUC-Ete-032626	Echinops telfairi	53.98	2.00e-178	619.00
IUUC-Eca-034208	Equus caballus	67.41	0.00e+00	1609.00
IUUC-Eeu-035340	Erinaceus europaeus	40.93	1.00e-62	234.00
IUUC-Fca-036006	Felis catus	79.15	2.00e-174	605.00
IUUC-Fal-036925	Ficedula albicollis	77.88	0.00e+00	1805.00
IUUC-Gmo-038597	Gadus morhua	46.06	0.00e+00	917.00
IUUC-Gga-041171	Gallus gallus	77.79	0.00e+00	1932.00
IUUC-Gac-041362	Gasterosteus aculeatus	47.34	0.00e+00	994.00
IUUC-Ggo-045069	Gorilla gorilla	63.67	0.00e+00	1414.00
IUUC-Hsa-046715	Homo sapiens	65.97	0.00e+00	1568.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	64.32	0.00e+00	1496.00
IUUC-Lch-050182	Latimeria chalumnae	53.87	0.00e+00	1191.00
IUUC-Loc-052705	Lepisosteus oculatus	56.43	0.00e+00	1341.00
IUUC-Laf-054132	Loxodonta africana	66.93	0.00e+00	1624.00
IUUC-Mcc-055734	Macaca mulatta	66.03	0.00e+00	1600.00
IUUC-Meu-056135	Macropus eugenii	83.26	5.00e-112	399.00
IUUC-Mga-060092	Meleagris gallopavo	76.24	0.00e+00	1875.00
IUUC-Mmr-061546	Microcebus murinus	63.10	0.00e+00	1478.00
IUUC-Mdo-061935	Monodelphis domestica	61.84	0.00e+00	1516.00
IUUC-Mmu-063630	Mus musculus	63.89	0.00e+00	1538.00
IUUC-Mpu-066579	Mustela putorius furo	64.79	0.00e+00	1606.00
IUUC-Mlu-068034	Myotis lucifugus	66.29	0.00e+00	1545.00
IUUC-Nle-069082	Nomascus leucogenys	61.88	0.00e+00	1257.00
IUUC-Opr-070953	Ochotona princeps	56.30	0.00e+00	754.00
IUUC-Ont-072435	Oreochromis niloticus	48.51	0.00e+00	1129.00
IUUC-Oan-073339	Ornithorhynchus anatinus	68.62	0.00e+00	1637.00
IUUC-Ocu-073760	Oryctolagus cuniculus	65.44	0.00e+00	1570.00
IUUC-Ola-087015	Oryzias latipes	47.33	0.00e+00	958.00
IUUC-Oga-088960	Otolemur garnettii	66.40	0.00e+00	1575.00
IUUC-Oar-089853	Ovis aries	65.52	0.00e+00	1568.00
IUUC-Ptr-091093	Pan troglodytes	66.05	0.00e+00	1573.00
IUUC-Pan-091962	Papio anubis	65.33	0.00e+00	1580.00
IUUC-Pma-094428	Petromyzon marinus	64.03	4.00e-87	314.00
IUUC-Pfo-096983	Poecilia formosa	48.49	0.00e+00	1043.00
IUUC-Pab-097860	Pongo abelii	64.67	0.00e+00	1445.00
IUUC-Pca-100514	Procavia capensis	66.01	1.00e-153	537.00
IUUC-Pva-102771	Pteropus vampyrus	64.58	0.00e+00	1446.00
IUUC-Rno-105405	Rattus norvegicus	63.41	0.00e+00	1534.00
IUUC-Sha-107376	Sarcophilus harrisii	62.88	0.00e+00	1466.00
IUUC-Ssc-115819	Sus scrofa	60.05	0.00e+00	1036.00
IUUC-Tgu-117262	Taeniopygia guttata	76.60	0.00e+00	1887.00
IUUC-Tru-117601	Takifugu rubripes	49.07	0.00e+00	1105.00
IUUC-Tsy-118996	Tarsius syrichta	57.18	0.00e+00	1202.00
IUUC-Tni-120682	Tetraodon nigroviridis	44.36	0.00e+00	887.00
IUUC-Tbe-127616	Tupaia belangeri	50.81	0.00e+00	929.00
IUUC-Ttr-129075	Tursiops truncatus	63.64	0.00e+00	1462.00
IUUC-Vpa-130108	Vicugna pacos	65.65	0.00e+00	1411.00
IUUC-Xtr-132623	Xenopus tropicalis	55.20	0.00e+00	1287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence