iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066605

Ensembl Protein ID

ENSMPUP00000013435.1

UniProt Accession

M3YQ27; M3YQ27_MUSPF

Genbank Protein ID

ENSMPUP00000013435

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01000845

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013538.1	ENSMPUT00000013651.1	ENSMPUP00000013435.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-41	136.8	640	672
UBD/Beta-Prp	4.50e-64	216.5	57	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt+++t++a+   +d++lvs+s+Dgt +vWD+
   Q: 640  GHTAKITSVAWsphHDGRLVSASYDGTAQVWDT 672
           8***********8766****************7 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t   v     h++++ +l++sp+  d +vsG++  ++ ++ l+ +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKAVVTEHALHQHTISALHWSPQVkDLIVSGDEKGVVFCYWLNRNDSQ 145
           7899**************965677***************************************555**************755555555 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls............fdsng............ 192
           +    ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++                +            
   Q: 146  H--HFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclsiN---Qeenseepeipng 228
           5..677777788888888888*****************999********9.*********7776666665430...2557788899999 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrtl 218
                       +l++gs+d+t+++w++++g+ v++l
   Q: 229  kvieqtpvtkgCYLATGSKDQTIRIWSCSRGRGVMIL 265
           99999999999******************99877765 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MGQDPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPSAGAIPG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKA VVTEHALHQH TISALHWSPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAAACTAA CTCTTTCTTT CCTTTTGATT TGATTCGAAC TTTTATCTTT TTGTTAACTG 60
GCTTGTTGTA GATGCTTGGA ATGAATCTCT AGAGCTGGCA AAGTGCCCTG GCACATAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	95.64	0.00e+00	2788.00
IUUC-Apl-003586	Anas platyrhynchos	61.71	0.00e+00	1613.00
IUUC-Aca-004956	Anolis carolinensis	62.43	0.00e+00	1856.00
IUUC-Ame-010753	Astyanax mexicanus	62.67	0.00e+00	1008.00
IUUC-Bta-012315	Bos taurus	88.13	0.00e+00	2630.00
IUUC-Cja-019334	Callithrix jacchus	87.25	0.00e+00	2641.00
IUUC-Cfa-021254	Canis familiaris	94.78	0.00e+00	2831.00
IUUC-Cpo-021984	Cavia porcellus	80.39	0.00e+00	2315.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.67	0.00e+00	2624.00
IUUC-Cho-024860	Choloepus hoffmanni	82.66	0.00e+00	2415.00
IUUC-Cin-025778	Ciona intestinalis	42.19	2.00e-159	556.00
IUUC-Csv-026313	Ciona savignyi	41.06	1.00e-165	576.00
IUUC-Dre-028096	Danio rerio	62.91	0.00e+00	1014.00
IUUC-Dno-029799	Dasypus novemcinctus	88.87	0.00e+00	2224.00
IUUC-Dor-030885	Dipodomys ordii	75.10	0.00e+00	1100.00
IUUC-Ete-032918	Echinops telfairi	80.77	0.00e+00	2412.00
IUUC-Eca-034144	Equus caballus	88.87	0.00e+00	2581.00
IUUC-Eeu-034843	Erinaceus europaeus	79.04	0.00e+00	1784.00
IUUC-Fca-035948	Felis catus	94.66	0.00e+00	2767.00
IUUC-Fal-037303	Ficedula albicollis	61.04	0.00e+00	1788.00
IUUC-Gmo-039591	Gadus morhua	53.01	0.00e+00	843.00
IUUC-Gga-040570	Gallus gallus	62.07	0.00e+00	1634.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.42	0.00e+00	1360.00
IUUC-Ggo-045605	Gorilla gorilla	80.95	0.00e+00	1834.00
IUUC-Hsa-046122	Homo sapiens	88.55	0.00e+00	2627.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.43	0.00e+00	2262.00
IUUC-Lch-050489	Latimeria chalumnae	51.54	0.00e+00	889.00
IUUC-Loc-052259	Lepisosteus oculatus	61.18	0.00e+00	982.00
IUUC-Laf-053338	Loxodonta africana	86.73	0.00e+00	2582.00
IUUC-Mcc-055442	Macaca mulatta	87.80	0.00e+00	2623.00
IUUC-Meu-056245	Macropus eugenii	82.96	0.00e+00	874.00
IUUC-Mga-060202	Meleagris gallopavo	62.23	0.00e+00	1689.00
IUUC-Mmr-061730	Microcebus murinus	87.44	0.00e+00	2611.00
IUUC-Mdo-062880	Monodelphis domestica	73.87	0.00e+00	2206.00
IUUC-Mmu-063930	Mus musculus	80.67	0.00e+00	2303.00
IUUC-Mlu-067765	Myotis lucifugus	90.51	0.00e+00	2704.00
IUUC-Nle-069183	Nomascus leucogenys	87.76	0.00e+00	2585.00
IUUC-Opr-070659	Ochotona princeps	75.11	0.00e+00	1169.00
IUUC-Ont-072356	Oreochromis niloticus	61.92	0.00e+00	1008.00
IUUC-Oan-073056	Ornithorhynchus anatinus	71.00	0.00e+00	2000.00
IUUC-Ocu-073881	Oryctolagus cuniculus	86.76	0.00e+00	2643.00
IUUC-Ola-087120	Oryzias latipes	57.49	8.00e-67	246.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.28	2.00e-30	127.00
IUUC-Oga-088343	Otolemur garnettii	88.04	0.00e+00	2634.00
IUUC-Oar-089257	Ovis aries	88.65	0.00e+00	2654.00
IUUC-Ptr-090497	Pan troglodytes	88.48	0.00e+00	2602.00
IUUC-Pan-092638	Papio anubis	87.49	0.00e+00	2611.00
IUUC-Psi-093096	Pelodiscus sinensis	64.37	0.00e+00	1624.00
IUUC-Pma-094571	Petromyzon marinus	44.14	5.00e-84	304.00
IUUC-Pfo-096742	Poecilia formosa	49.01	0.00e+00	1384.00
IUUC-Pab-098153	Pongo abelii	88.02	0.00e+00	2664.00
IUUC-Pca-100957	Procavia capensis	80.56	0.00e+00	2390.00
IUUC-Pva-102439	Pteropus vampyrus	91.14	0.00e+00	2714.00
IUUC-Rno-105891	Rattus norvegicus	81.19	0.00e+00	2302.00
IUUC-Sha-107181	Sarcophilus harrisii	73.92	0.00e+00	2098.00
IUUC-Ssc-115413	Sus scrofa	88.46	0.00e+00	2692.00
IUUC-Tgu-117082	Taeniopygia guttata	62.95	0.00e+00	1781.00
IUUC-Tru-118491	Takifugu rubripes	59.89	0.00e+00	954.00
IUUC-Tsy-119629	Tarsius syrichta	96.19	2.00e-171	597.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.62	0.00e+00	955.00
IUUC-Tbe-127673	Tupaia belangeri	76.67	0.00e+00	2113.00
IUUC-Ttr-128562	Tursiops truncatus	85.99	0.00e+00	2571.00
IUUC-Vpa-130596	Vicugna pacos	85.42	0.00e+00	1889.00
IUUC-Xtr-132469	Xenopus tropicalis	54.93	0.00e+00	1600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence