iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117082

Ensembl Protein ID

ENSTGUP00000000708.1

UniProt Accession

H0YR01; H0YR01_TAEGU

Genbank Protein ID

ENSTGUP00000000708

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01019956

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000000688.1	ENSTGUT00000000719.1	ENSTGUP00000000708.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.20e-40	132.9	628	665
UBD/Beta-Prp	7.40e-63	212.3	50	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt+++t+l++  +  ++lvs+++Dgt +vWD+ +  +
   Q: 628  GHTAKITSLSWspHHeGRLVSACYDGTAQVWDVMKEEP 665
           8***********733699**************977665 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcle 130
           r+l gh++ ++   f +      + +++s+D+ +kvwd  t ++v  ++ h++ + +l++sp  +d +vsG++  +i ++ +++++ ++
   Q: 50   RELVGHTDRISGFAFCHCPGqssLCASSSDDGSVKVWDSGTLSPVLEYSLHQNAISALHWSPlVKDLIVSGDEKGVIVCY-WHNRSDSQ 137
           5778888888777766543234599*************************************888**************8.77888887 PP
   S: 131  etlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...................fdsng...... 192
             + ++ ++v c++ +p   nl++ G +D++v + d+ +  +++++l+g h+d +++l+                       g      
   Q: 138  -QFFPEPRTVFCLTCSPHHeNLVAIGYKDGMVVIIDIsRKREVVHRLRG-HEDEIHCLAwcpvpgeerlpawqnelqeE---Gkvpnge 221
           .6888888899999999988*****************78889******9.*********88888888888766664440...1666666 PP
   S: 193  ..........kelvsgsldgtvklwdlqtgecvrtlng 220
                      +l+sgs+d+t+++w++ +g+ v+tl+ 
   Q: 222  lpqdtatrkgCYLASGSKDQTIRIWSCTRGRSVMTLKL 259
           6666666666**********************999875 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

RALPASPNWY SSRCSDASSD GRLFGFAARH RVCLLDVAAA PAVGRPRVPR ELVGHTDRIS 60
GFAFCHCPGQ SSLCASSSDD GSVKVWDSGT LSPVLEYSLH QNAISALHWS PLVKDLIVSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGCGCTCC CCGCCTCCCC CAACTGGTAC AGCAGCCGCT GCAGCGATGC CAGCAGTGAC 60
GGCCGCCTCT TCGGCTTCGC GGCGAGGCAC CGCGTCTGCC TGCTGGATGT GGCCGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	63.10	0.00e+00	1813.00
IUUC-Apl-003586	Anas platyrhynchos	83.65	0.00e+00	2231.00
IUUC-Aca-004956	Anolis carolinensis	66.98	0.00e+00	1969.00
IUUC-Ame-010753	Astyanax mexicanus	64.91	0.00e+00	999.00
IUUC-Bta-012315	Bos taurus	63.20	0.00e+00	1823.00
IUUC-Cja-019334	Callithrix jacchus	62.38	0.00e+00	1811.00
IUUC-Cfa-021254	Canis familiaris	63.30	0.00e+00	1847.00
IUUC-Cpo-021984	Cavia porcellus	61.01	0.00e+00	1697.00
IUUC-Csa-023650	Chlorocebus sabaeus	63.01	0.00e+00	1799.00
IUUC-Cho-024860	Choloepus hoffmanni	59.18	0.00e+00	1628.00
IUUC-Cin-025778	Ciona intestinalis	40.53	4.00e-152	531.00
IUUC-Csv-026313	Ciona savignyi	40.11	1.00e-156	546.00
IUUC-Dre-028096	Danio rerio	65.37	0.00e+00	1009.00
IUUC-Dno-029799	Dasypus novemcinctus	65.36	0.00e+00	1650.00
IUUC-Dor-030885	Dipodomys ordii	54.89	0.00e+00	817.00
IUUC-Ete-032918	Echinops telfairi	60.19	0.00e+00	1692.00
IUUC-Eca-034144	Equus caballus	62.00	0.00e+00	1785.00
IUUC-Eeu-034843	Erinaceus europaeus	59.22	0.00e+00	1319.00
IUUC-Fca-035948	Felis catus	62.90	0.00e+00	1809.00
IUUC-Fal-037303	Ficedula albicollis	91.87	0.00e+00	2742.00
IUUC-Gmo-039591	Gadus morhua	54.51	0.00e+00	830.00
IUUC-Gga-040570	Gallus gallus	83.11	0.00e+00	2193.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.87	0.00e+00	1329.00
IUUC-Ggo-045605	Gorilla gorilla	59.62	0.00e+00	1332.00
IUUC-Hsa-046122	Homo sapiens	62.60	0.00e+00	1799.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	66.15	0.00e+00	1650.00
IUUC-Lch-050489	Latimeria chalumnae	49.57	0.00e+00	873.00
IUUC-Loc-052259	Lepisosteus oculatus	63.03	0.00e+00	965.00
IUUC-Laf-053338	Loxodonta africana	62.97	0.00e+00	1800.00
IUUC-Mcc-055442	Macaca mulatta	62.88	0.00e+00	1795.00
IUUC-Meu-056245	Macropus eugenii	71.07	0.00e+00	717.00
IUUC-Mga-060202	Meleagris gallopavo	83.49	0.00e+00	2286.00
IUUC-Mmr-061730	Microcebus murinus	61.92	0.00e+00	1757.00
IUUC-Mdo-062880	Monodelphis domestica	64.36	0.00e+00	1854.00
IUUC-Mmu-063930	Mus musculus	62.39	0.00e+00	1715.00
IUUC-Mpu-066605	Mustela putorius furo	62.72	0.00e+00	1821.00
IUUC-Mlu-067765	Myotis lucifugus	62.93	0.00e+00	1834.00
IUUC-Nle-069183	Nomascus leucogenys	62.20	0.00e+00	1752.00
IUUC-Opr-070659	Ochotona princeps	52.48	0.00e+00	726.00
IUUC-Ont-072356	Oreochromis niloticus	50.20	0.00e+00	1404.00
IUUC-Oan-073056	Ornithorhynchus anatinus	65.34	0.00e+00	1817.00
IUUC-Ocu-073881	Oryctolagus cuniculus	63.02	0.00e+00	1855.00
IUUC-Ola-087120	Oryzias latipes	60.29	2.00e-66	244.00
IUUC-Olu-087648	Ostreococcus lucimarinus	24.95	4.00e-31	129.00
IUUC-Oga-088343	Otolemur garnettii	62.68	0.00e+00	1825.00
IUUC-Oar-089257	Ovis aries	63.37	0.00e+00	1843.00
IUUC-Ptr-090497	Pan troglodytes	62.26	0.00e+00	1789.00
IUUC-Pan-092638	Papio anubis	62.71	0.00e+00	1787.00
IUUC-Psi-093096	Pelodiscus sinensis	72.41	0.00e+00	1826.00
IUUC-Pma-094571	Petromyzon marinus	54.29	2.00e-65	242.00
IUUC-Pfo-096348	Poecilia formosa	50.10	0.00e+00	1338.00
IUUC-Pab-098153	Pongo abelii	62.30	0.00e+00	1786.00
IUUC-Pca-100957	Procavia capensis	60.11	0.00e+00	1698.00
IUUC-Pva-102439	Pteropus vampyrus	62.92	0.00e+00	1849.00
IUUC-Rno-105891	Rattus norvegicus	62.12	0.00e+00	1695.00
IUUC-Sha-107181	Sarcophilus harrisii	65.28	0.00e+00	1839.00
IUUC-Ssc-115413	Sus scrofa	63.35	0.00e+00	1821.00
IUUC-Tru-118491	Takifugu rubripes	61.34	0.00e+00	942.00
IUUC-Tsy-119629	Tarsius syrichta	70.83	4.00e-125	442.00
IUUC-Tni-120240	Tetraodon nigroviridis	62.23	0.00e+00	948.00
IUUC-Tbe-127673	Tupaia belangeri	55.29	0.00e+00	1468.00
IUUC-Ttr-128562	Tursiops truncatus	60.69	0.00e+00	1736.00
IUUC-Vpa-130596	Vicugna pacos	63.64	0.00e+00	1382.00
IUUC-Xtr-132469	Xenopus tropicalis	56.78	0.00e+00	1630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence